@pitepit_

Immunologist @KalliesLab @TheDohertyInst @UniMelb now working for pharma

 Melbourne, Victoria
Joined December 2018
  • Tweets41
  • Following104
  • Followers208
4Media
I’m super excited to share the latest publication of Team #TPEX, @UtzschneiderD, Axel Kallies and myself in @ImmunityCP, where we explore the secrets of #TPEX metabolic longevity with implications in #Immunotherapy. Short #tweetorial below: cell.com/immunity/fulltext/S…

Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain...

Exhausted T cells are heterogenous, consisting of subpopulations with different functional and developmental properties. Gabriel et al. demonstrate that TGF-β-mediated mTOR inhibition preserves the...

cell.com
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Bedoui and colleagues describe how antigen presenting cells integrate innate stimuli and CD40 signaling from CD4+ T cells to drive antiviral CD8+ T cell responses. Read it here: rdcu.be/dcNTT nature.com/articles/s41590-0…
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I’m absolutely stoked to see a side project of mine being brought to the next level by my friend Carlson Tsui @KalliesLab and collaborators @LoKretschmer & Svenja Rapelius @VeitBuchholz lab. Published today @nature! @UniMelb @TheDohertyInst @TU_Muenchen nature.com/articles/s41586-0…
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Congrats to everyone involved! @d_chisanga @TeishaM @UtzschneiderD @KKnoepper @s_nuessing Yang Liao @Santiago_VaTo Stephen Wilcox @IanParish_AU Stephen Nutt, Dietmar Zehn @Kamu_Lab & Wei Shi @UniMelbMDHS @wehi @ONJCRI @Wue_SI @PeterMacRes @ASImmunology #Tcellexhaustion #Tpex
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Great commentary on our recent work by Dietmar Zehn and Anna Schulz 👇👇
ICB - the journal@ImmunolCellBiol16 Feb 2022
An #ICBnews and commentary: Anna Schulz & Dietmar Zehn discuss how CD8+ T cells fine-tune their metabolic fitness to maintain long-term T cell responses based on a paper by @pitepit_ et al in @ImmunityCP. @UniMelbMDHS @TheDohertyInst onlinelibrary.wiley.com/doi/…

Immunology & Cell Biology | ASI Journal | Wiley Online Library

A recent study by Gabriel et al. provides novel insight into the metabolic pathways that contribute to T cell differentiation in chronic infection. The researchers discovered that metabolic plastic...

onlinelibrary.wiley.com
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Sarah Gabriel retweeted
Lugli Lab@luglilab27 Jul 2021
Join this fantastic group of scientists. We’re hiring!! Info below 👇🏼
Lugli Lab@luglilab12 Jul 2021
WE ARE HIRING #postdoctoral in Milan to study stem-like T cell responses and Treg-mediated inhibition in human #cancer #Immunotherapy and a technician to support research activities. Positions available for up to 5 years. Details below 👇. Email me for more information
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If you don't know them yet: 'Accelerating Cancer Immunotherapy Research' @ACIR_org is on a mission to provide a weekly synopsis of the key advances in the field of cancer immunotherapy to clinicians, researchers and the public. Thanks for highlighting our work in @ImmunityCP!
ACIR
@ACIR_org22 Jul 2021
SPOTLIGHT: Transforming growth factor-b-regulated mTOR activity [...] @TheDohertyInst @UniMelbMDHS @TheRMH @WEHI_research @UtzschneiderD @pitepit_ @UniMelb. Originally published in @ImmunityCP. To read our summary click bit.ly/3ziopG8 and scroll all the way down.
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3/ Comparing infections with a race, our study suggests a model where #TEX cells run off at full speed and thereby quickly exhaust. #TPEX cells in contrast start much slower thanks to supressed #mTOR, and thereby are prepared to run the marathon ahead (chronic infection).
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4/ Many thanks to everyone involved! @TeishaM for expert help, Carlson Tsui, Flora Weber, Manuela Ilano-Leon and Patrick Gubser @TheDohertyInst @UniMelbMDHS, @mubadav and Wei Shi @ONJCRI, @Dr_Nick_Bikes @MonashBDI and @Fer_NK_nando, and @snsf_ch, @nhmrc @LLSusa for our funding.
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Sarah Gabriel retweeted
HoLab@PCHo_Lab22 Jun 2021
It is great to host Axel Kallies for Ludwig seminar in our institute. I am still very impressed by the works done by @pitepit_ and @UtzschneiderD ! Looking forward to the development of our collaborative work🙏
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👇👇👇 🥳🎉🎊
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Tune in to listen to two amazing @TheDohertyInst scientists @BedouiSammy @pitepit_ 2nd Melbourne Immunometabolism symposium #melbimmmetabsym
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We #TeamTpex - @UtzschneiderD, Axel Kallies and I - have looked into the early development of T cell exhaustion, published today in @NatImmunol! Thanks to everyone involved and especially @mubadav @TheDohertyInst @UniMelbMDHS @WEHI_research nature.com/articles/s41590-0…
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and a big thank you to @teisha_m for all her support throughout the study!
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Exciting new research has identified mechanisms leading to the functional deterioration of the immune system in response to infections, such as #HIV or #COVID19. Led by @UtzschneiderD, @pitepit_ &Axel Kallies it was published in @NatImmunol today. doherty.edu.au/news-events/n…

Severe viral infection overwhelms immune cells - Doherty Institute

doherty.edu.au
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Interested in metabolism and the immune system? Join us for the Melbourne Immunometabolism Symposium on 1st/2nd September! 👇👇👇👇
ASI - Immunometabolism SIG@Immetab_asi9 Aug 2020
We are excited to present the 2nd Melbourne Immunometabolism Symposium!! Join us virtually September 1st & 2nd 2020 (9:30am - 2:00pm AEST). To register DM @ajithvasanthan or @AJMurph5. Don't miss the amazing line-up of speakers!! @ASImmunology #immunometabolism #symposium
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I'm super proud of you @ajithvasanthan and the rest of the Kallies team!!! @nature @TheDohertyInst @WEHI_research nature.com/articles/s41586-0…
Ajith Vasanthakumar@ajithvasanthan26 Feb 2020
Excited to share our latest research published today in @nature on sex-differences in adipose resident Treg cells @TheDohertyInst @WEHI_research @ASImmunology. Big thanks to our collaborators from @MonashPharm @PeterMacCC @Austin_Health @harvardmed nature.com/articles/s41586-0…

Sex-specific adipose tissue imprinting of regulatory T cells

Nature - Visceral adipose tissue contains populations of regulatory T cells that exhibit sexual dimorphism, determined by the surrounding niche, and differ between male and female mice in terms of...

nature.com
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Kallies lab celebrating the @TheDohertyInst #christmas party 🎄 @ajithvasanthan @UtzschneiderD
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