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Causes and consequences of chronic systemic inflammation (from our new paper nature.com/articles/s41591-0… at @NatureMedicine )
Pedro Carrera Bastos retweeted
Epigenetics Update - Cardiovascular resilience in centenarians nature.com/articles/s41569-0…
@pmcbastos, José Antonio Serra-Rexach, and Alejandro Lucia in Nature Reviews Cardiology
#Epigenetics #Review #Centenarians #Aging
Pedro Carrera Bastos retweeted
Cardiovascular resilience in centenarians
"Understanding the biological, behavioural and environmental mechanisms underlying cardiovascular resilience in extreme longevity might inform strategies to extend cardiovascular healthspan across all ages..."
nature.com/articles/s41569-0…
Pedro Carrera Bastos retweeted
The cardiovascular resilience of #centenarians does not come from an absence of aging or disease, but from a delayed onset of cardiovascular pathology and the preservation of the body’s adaptive compensatory capacity.
A new review led by @pmcbastos:
nature.com/articles/s41569-0…
What can centenarians teach us about cardiovascular ageing?
Happy to share our new review in Nature Reviews Cardiology, exploring the mechanisms that may support cardiovascular resilience at 100+.
nature.com/articles/s41569-0…
Pedro Carrera Bastos retweeted
Check out our Spotlight article "Exerkine GPLD1 bridges liver and brain," (dlvr.it/TSVYCJ) published in Cell Metabolism @Cell_Metabolism
@pmcbastos
Pedro Carrera Bastos retweeted
Check out our Review article "The long-lived immune system of centenarians," published in Nature Reviews Immunology @NatRevImmunol
@InmaPerezPrieto @pmcbastos
nature.com/articles/s41577-0…
Pedro Carrera Bastos retweeted
The immune system in centenarians is remarkably youthful, far less prone to inflammaging
@NatRevImmunol nature.com/articles/s41577-0…
Our new paper exploring what makes centenarians unique from an immune system perspective is now out
The long-lived immune system of centenarians dlvr.it/TSBZXC
Our new paper in Nature Reviews Immunology is out: The immune system of centenarians.
A huge thank you to all co-authors, especially @Abeladrian94 , Carmen Fiuza-Luces, and Alejandro Lucia. A special acknowledgement to @InmaPerezPrieto for the outstanding figures.
Pedro Carrera Bastos retweeted
Our new paper on reassessing the heritability of human lifespan is out in @ScienceMagazine! 🧬
For decades, the consensus has been that genetics explains just 20–25% of lifespan differences. We found that after accounting for extrinsic mortality, that number jumps to ~50%.
A 🧵
Multilingualism protects against accelerated aging in cross-sectional and longitudinal analyses of 27 European countries nature.com/articles/s43587-0…
The Warburg effect may be involved not only in various types of cancer but also in metabolic and endocrine disorders such as type 2 diabetes.
This is the central topic of our recent review available here:
link.springer.com/article/10…
Pedro Carrera Bastos retweeted
Check out our new article "Tumor Signatures of Physical Fitness: Insights from a Preclinical Model" published in
@MSSEonline
@pmcbastos @InmaPerezPrieto
pubmed.ncbi.nlm.nih.gov/4085…
Pedro Carrera Bastos retweeted
Happy to share our last work @pmcbastos! Now in 'Aging Cell'
@Aging_Cell
Even at 100+: Acute Exercise Modulates Inflammatory Pathways in Centenarians
onlinelibrary.wiley.com/doi/…
Pedro Carrera Bastos retweeted
The ‘autoimmunome’ of centenarians. Could albumin and complement be the key to preventing autoimmune diseases? sciencedirect.com/science/ar… @pmcbastos
Pedro Carrera Bastos retweeted
The connection between chronic inflammation and depression continues to gain empirical strength. Framing physical activity through an evolutionary lens adds depth to our understanding that movement isn't just therapy, it's biology in action. @pmcbastos #MentalHealth #Inflammation
Systemic low-grade chronic inflammation plays a central role in the development and progression of depression
@pmcbastos & colleagues suggest an evolutionary framework for the role of physical activity and exercise for tackling inflammation:
loom.ly/Hmjh2bU
Pedro Carrera Bastos retweeted
Systemic low-grade chronic inflammation plays a central role in the development and progression of depression
@pmcbastos & colleagues suggest an evolutionary framework for the role of physical activity and exercise for tackling inflammation:
loom.ly/Hmjh2bU
I’m excited to share our latest review on prolactin’s role in autoimmunity, led by my dear friend Vânia Borba and published in Autoimmunity Reviews:
sciencedirect.com/science/ar…






















