Epidemiology, viruses, emergence, evolution Joint Research Centre London School of Hygiene & Tropical Medicine Formerly: ECDC, Uni of Oxford Opinions are my own
Joined March 2015
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Our review paper on the evolution of SARS-CoV-2 with @ArisKatzourakis, @Mahan_Ghafari, @Simmonds_Lab, @katrina_lythgoe just out in @NatureRevMicro nature.com/articles/s41579-0…
📌Our latest work is out!
Effectiveness of remdesivir treatment and early hospitalisation against COVID-19.
Modelling driven by fearsomely skilled and effective @SchuhLea. Check out her🧵and read the paper🎯
How effective are treatments against COVID-19? 🦠💉😷
Check out our newest publication in #JRSocInterface and take a 👀
royalsocietypublishing.org/d… 🎉
A short 🧵
"We embedded the overall effectiveness of the activity of the immune capacity against SARS-CoV-2 within the quantity, representing the combined effects of innate immunity, adaptive immunity, and immune memory on the ability to control the virus."
📢Two exciting positions to work on #AI, #MachineLearning & #LLMs
🚀 with some very smart, nice and productive people
🎯 at the @EU_ScienceHub in Ispra, Northern Italy.
🔎Details below.
Peter Markov retweeted
WITHIN-HOST (re)INFECTION DYNAMICS of SARS-CoV-2
(very interesting study from @pvmarkov and colleagues)
sciencedirect.com/science/ar…
Our work on withinhost reinfection dynamics of SARS-CoV-2 w/ @SchuhLea et al. at @EU_ScienceHub now published in #MathematicalBiosciences
We model reinfections with higher infectivity & immune escape
- Find🧵with the key points below
- The paper is here: sciencedirect.com/science/ar…
Our new #preprint on “A mathematical model for the within-host (re)infection dynamics of SARS-CoV-2” is out on @arxiv! 📄🦠💻😷
Thanks to @pvmarkov, Vladimir Veliov and Nikolaos Stilianakis for this collab! 🙏
arxiv.org/abs/2312.04607
A quick 🧵.
👉5 more days to apply!
A postdoc with us (near Milano, Italy) to riskmap local transmission of tropical fevers in EU
📣Exciting research
📣Productive team
📣Freedom to formulate questions
📣Excellent pay & work conditions
with @pvmarkov
at @EU_ScienceHub
iddjobs.org/jobs/research-po…
📢Our work on SARS-CoV-2 within-host dynamics led by @SchuhLea in collaboration with Prof Vladimir Veliov from @tu_wien now out in preprint
Of note, we investigate properties of viral & immune dynamics upon reinfection with variants featuring:
👉Higher infectivity
👉Immune escape
Our new #preprint on “A mathematical model for the within-host (re)infection dynamics of SARS-CoV-2” is out on @arxiv! 📄🦠💻😷
Thanks to @pvmarkov, Vladimir Veliov and Nikolaos Stilianakis for this collab! 🙏
arxiv.org/abs/2312.04607
A quick 🧵.
Peter Markov retweeted
👍CHART to understand the difference between INTRINSIC and DISEASE SEVERITY
and that "the notion that viruses will evolve to be less virulent to spare their hosts is one of the most persistent myths surrounding pathogen evolution."
Thx to @yaneerbaryam
nature.com/articles/s41579-0…
Great 🧵by @LongDesertTrain on historical & political constraints on acceptance of airborne spread for SARS-CoV-2 and other major pathogens. 🎯
Chaplin's view was influential—not because the evidence favored droplet transmission but because his views led to politically acceptable conclusions. With droplet transmission no public action or business regulation was required. @BenEhrenreich: 2/3 thebaffler.com/salvos/airbor…
@ejustin46, thanks for using our work to illustrate your nice post! Just a minor correction:
The statement "MUTATION rate is 'the rate at which a virus evolves'" in your post is incorrect. We don't say this in our paper, but the use of quotation marks seems to imply so.
2) The excellent study “The evolution of SARS-CoV-2” clarifies the difference between the 2 rates :
The MUTATION rate is "the rate at which a virus evolves. This is the intrinsic rate at which genetic changes emerge per replication cycle"
nature.com/articles/s41579-0…
We say: "A key determinant of the rate at which a virus evolves is its mutation rate" which means a different thing. "The rate at which a virus evolves" is a definition of the substitution rate, rather than the mutation rate.
@Mahan_Ghafari
@ArisKatzourakis
@NatureRevMicro
Thanks @MarionKoopmans! No better credit than seeing my figure in the lecture theatre! @NatureRevMicro
Preparing for teaching, master students update on key outstanding questions after they did their own SARS COV 2 case studies. Really like this figure in nat mic review published earlier this year, that is an excellent description of viral diversity nature.com/articles/s41579-0…
Peter Markov retweeted
Celebrating 20 years of Nature Reviews Microbiology and progress in the field! 🥳🎉
We're immensely grateful for the extraordinary support from our dedicated community of readers, authors and peer-reviewers over two decades 🙌📚✍️💖
Here's to the next 20 years of progress!
🎉🥳 Happy 20th anniversary to us! 🥳🎉
Our October issue is now live, marking 20 years since our launch in 2003 📚🔬✨
Please join us in celebrating and read the issue here: go.nature.com/48eKMyn
Explore our special anniversary collection here: go.nature.com/48ckNaN
🚀Two final days still left to submit applications for this post, combining interesting epidemiological science 🔭, great geographical location🎯, outstanding remuneration💶& conditions of work👩🎓
👉We are hiring. Again!
A new post to work on combining indicator & event based infection surveillance + map risk of emergence
📣Exciting research
📣Freedom to choose your questions within the topic 📣Attractive pay
📣In our Belgian campus not far from Brussels
@EU_ScienceHub
📢These two Postdoc positions are closing tonight. You still have time to file in your application and carry out some cool research🔬with us at the JRC in the next 3 years! 🚀
👉We are hiring! Two posts to study & risk map infection emergence in EU
📣Exciting research
📣Productive team
📣Freedom to formulate questions
📣North Italy: wealth of culture, history, outdoors, good food & stunning nature
📣Excellent pay & work conditions
@EU_ScienceHub
Peter Markov retweeted
@EU_ScienceHub is great place to work 👍
👉We are hiring! Two posts to study & risk map infection emergence in EU
📣Exciting research
📣Productive team
📣Freedom to formulate questions
📣North Italy: wealth of culture, history, outdoors, good food & stunning nature
📣Excellent pay & work conditions
@EU_ScienceHub
👉We are hiring! Two posts to study & risk map infection emergence in EU
📣Exciting research
📣Productive team
📣Freedom to formulate questions
📣North Italy: wealth of culture, history, outdoors, good food & stunning nature
📣Excellent pay & work conditions
@EU_ScienceHub
2 Postdocs (Ispra (near Milano), Italy) Investigate environmental and non-environmental factors for emergence of infections and develop risk maps of emergence in Europe
with
@pvmarkov, Nikolaos Stilianakis
at @EU_ScienceHub
More details: iddjobs.org/jobs/two-researc…
📢This opportunity closes in just six days now!
If you want to:
🚀Work on a cool & exciting epi projects 🔭
📰Publish well🏆
🤖Work with nice people🧛♂️
💰Get enviable work and pay conditions🔬
🎯Don't forget to apply by 30 May!
👉We are hiring. Again!
A new post to work on combining indicator & event based infection surveillance + map risk of emergence
📣Exciting research
📣Freedom to choose your questions within the topic 📣Attractive pay
📣In our Belgian campus not far from Brussels
@EU_ScienceHub
Peter Markov retweeted
Happy 102nd birthday to Sir Anthony Epstein. The virus he discovered with Yvonne Barr and Bert Achong in 1964 continues to surprise us! Most recently implicated in multiple sclerosis and long covid, EBV also plays a role in certain cancers. Important therapeutic target.
Peter Markov retweeted
👍 It’s for me to thank @pvmarkov and all #F7DigitalHealth colleagues for the fascinating presentations! Be it surveillance of infectious diseases or bioinformatics, be it health related application of data science or AI or knowledge on mental health, you do super job!👏
🎯Inspiring one hour with @SallaLoi, Deputy Director-General, Joint Research Centre @EU_ScienceHub with us at #F7DigitalHealth today. A great chance for ourselves to reflect on how much we do + impressive to see a senior leader who listens, takes interest and asks questions🔭
🎯Inspiring one hour with @SallaLoi, Deputy Director-General, Joint Research Centre @EU_ScienceHub with us at #F7DigitalHealth today. A great chance for ourselves to reflect on how much we do + impressive to see a senior leader who listens, takes interest and asks questions🔭