Rose Knows

They always knew ivermectin and fenben would be effective. They lied and millions died because of it. This document is a declassified **CIA intelligence report** from February 1951 (distributed 26 Feb 1951), summarizing an article originally published in the Soviet scientific journal *Priroda* (Nature), Vol. XXXIX, No. 10, pp. 22–27, dated October 1950. The report is marked **CONFIDENTIAL** (later declassified and sanitized/released under FOIA in 2011, document ID CIA-RDP80-00809A000600380033-3). It falls under the category "50X1-HUM" (a CIA code for human-source intelligence from foreign documents or broadcasts, often USSR-related scientific/medical info during the Cold War). The CIA collected and translated/summarized foreign scientific publications for potential military, medical, or strategic value. ### Title of the Summarized Article **BIOCHEMICAL RESEMBLANCE BETWEEN ENDOPARASITES AND MALIGNANT TUMORS** Author: Prof. V. V. Alpatov (or V. Alpatov; likely a Soviet biologist or parasitologist) ### Key Content Summary (Transcribing/Correcting the OCR'd Text for Clarity) The report states this is **un-evaluated information** (meaning the CIA didn't verify its scientific accuracy; they just passed it along). Main points from the article summary: - **Endoparasites** (internal parasitic worms living in the intestines) and **malignant tumors** (cancers) resemble each other in many ways due to similar growth conditions and existence. - Both exhibit **pronounced anaerobic metabolism** (they thrive in low-oxygen environments) and accumulate large quantities of **glycogen** (a stored form of sugar/energy) in their tissues. - Parasitic worms and cancer tissues share similar **amphibolic (adaptable) metabolism** — able to function under both aerobic (with oxygen) and anaerobic conditions. - In 1938, H. Mauss synthesized a compound called **alkylated aminoanthraquinone Myrcayl B** (or similar; text has typos like "Myracyl B" — likely an early experimental drug), and later work by G. Kidder on **5-amino-7-hydroxy-1-v-triazolo(d)pyrimidine** (a guanine analog/purine derivative) showed it could suppress nucleic acid synthesis. - These compounds were tested and found effective against parasites like **Schistosoma** (Bilharzia) and also had activity against malignant tumors in mice. - The author (Alpatov), along with others like Matyukova, tested **atebrin enanthiomorphs** (likely optical isomers or variants of **atebrin/quinacrine**, an old anti-malarial drug) on various animals. - They found that most test animals (especially **laboratory spiral nematodes**? — text garbled; possibly referring to specific worm species) and malignant tumors (e.g., adenocarcinoma in mice, frog intestinal gland cancer) were highly sensitive to one form of the compound. - Parasitic worms in the intestines showed an opposite reaction to non-parasitic worms when exposed to these enanthiomorphs (one form toxic to parasites/tumors, the other perhaps not, or vice versa). - The tissues of tumors and parasitic worms can be distinguished from healthy tissue by their reaction to these optically active compounds. The document is only 2 pages, ends abruptly with classification markings (CONFIDENTIAL, distribution limits to State/ Army/ Navy/ Air/ FBI), and includes standard disclaimers about it containing info affecting U.S. national defense (Espionage Act warning). ### Context During the early Cold War, the CIA monitored Soviet scientific literature closely (via programs like FDD — Foreign Documents Division) for anything that might relate to biological warfare, medical breakthroughs, or propaganda. Ideas linking parasites and cancer were fringe even then (though some metabolic similarities exist, like Warburg effect in cancer cells favoring anaerobic glycolysis). No mainstream cancer treatment emerged from this line of Soviet research. I