Computational genomicist. Interests include transcription and transcriptional regulation. Assoc. Prof. at Univ. of Copenhagen. @randersson.bsky.social
Copenhagen
Joined January 2011
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Very much looking forward to the Genomic Mechanisms of Disease Conference, 8-12 March 2027 in Hillerød!
Fantastic speakers across genomics, gene regulation, computational biology & disease mechanisms!
The call for abstracts is open.
Apply by 15 Nov:
sciencecluster.dk/event/conf…
Thrilled to share that our scE2G paper is now published in @NatureGenet!
nature.com/articles/s41588-0…
scE2G predicts enhancer-gene regulatory interactions from single-cell data with state-of-the-art performance.
Amazing work led by @mayayayas and @613weilin!
Update: scE2G is now online at @NatureGenetics!
📄 nature.com/articles/s41588-0…
Since the preprint, we added a new benchmark on a fully held-out CRISPR dataset.
scE2G continues to show state-of-the-art performance, reinforcing that it generalizes well
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Latest from the lab! Led by @XueningHe922, establishing a framework for interpretation of the motif syntax of regulatory elements and a quantitative model for TF cooperativity. Plenty of cool stuff revealed, including TF redundancy and synergy, and their regulatory roles!
Excited to share DeepCompARE + ISA - a lightweight deep learning model + efficient interpretation method, to uncover rules of TF cooperativity via genome-wide in silico motif ablations!
Preprint: biorxiv.org/content/10.1101/…
Github: github.com/anderssonlab/Deep…
🚨Job alert! 🚨
We are hiring a computational postdoc or PhD student focusing on
- modeling gene regulation using single cell data
- investigating the mechanisms of regulatory genetic variants
PhD student: employment.ku.dk/all-vacanci…
Postdoc: employment.ku.dk/faculty/?sh…
Check out our latest work, scE2G, for mapping the target genes of enhancers from single cell data! biorxiv.org/content/10.1101/…. See 🧵 below for highlights
Amazing work led by co-first authors @mayayayas and @613weilin in a great collaboration with @jengreitz 's lab
Excited to share our latest preprint on scE2G – a new model to link enhancers to target genes using single-cell data – with state-of-the-art performance across multiple perturbation benchmarks.
biorxiv.org/cgi/content/shor…
Read more below!
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Robin Andersson retweeted
Happy to share our joint work with the Falsig Pedersen group on how the physical microenvironment can drive cells to acquire cancer hallmarks. cell.com/cell-reports/fullte… . In solid tumors, niches with low pH are common. We show that pancreatic cancer and normal organoids...(1/N)
Robin Andersson retweeted
Sooooo excited to share the first paper from the lab now online @NatureGenet 😀😀😀
Interested in MYC, transcriptional mechanisms and (breast) cancer? Check it out👉rdcu.be/dAAht.
Short summary thread 👇
Robin Andersson retweeted
A true curiosity-driven journey, fulfilling one of my childhood dreams! The tail loss marks a pivotal evolutionary step towards humans and apes. But how did it happen? rdcu.be/dzTba @ItaiYanai @JefBoeke
How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. nature.com/articles/s41586-0… @BoXia7
Robin Andersson retweeted
7 days left to apply for our #postdoc position on RNA modifications at the University of Copenhagen!
If you’re interested in combining #CRISPR with #nanopore direct RNA sequencing to explore the role of #RNAmodifications in #RNAdegradation, apply here!
employment.ku.dk/all-vacanci…
Robin Andersson retweeted
An encyclopedia of enhancer-gene regulatory interactions in the human genome
xitter.cf/argschwind/status/1724…
Very proud—4 years in the making, huge team effort.
This is a paper where the author list cannot convey everyone's incredible contributions.
My holiday highlights below:
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Excited to share our latest work on bioRxiv!
biorxiv.org/content/10.1101/…
A highly collaborative effort with @ksmualim @karbalayghareh, @mayayayas, @kanishkadey, @evelynjagoda,@WangXijhu, @LarsMSteinmetz, @anshulkundaje, @jengreitz and many others from @ENCODE_NIH!
Thread👇
Robin Andersson retweeted
“Transposable elements contribute to nearly 80% of human-specific candidate cis-regulatory elements in cortical cells” 🧠 …🤯 literally! Amazing dataset 🔥 Congrats to all involved!
nature.com/articles/s41586-0…
Robin Andersson retweeted
🧬Opening for a postdoc in my group @NCMMnews @UniOslo @UniOslo_MED @unioslo_mn to generate deep learning models to enhance JASPAR @jaspar_db & UniBind, boosting gene regulation research. Project in collaboration with @anshulkundaje, @WyWyWa.
Plz share
jobbnorge.no/en/available-jo…
Robin Andersson retweeted
Come and join us!
We are looking to recruit a Research Assistant/Technical Associate I to join our team Summer 2024.
This could be an ideal position for someone looking for 2 years of research experience before starting graduate school.
Apply: careers.peopleclick.com/care…
Robin Andersson retweeted
Congratulations to all our students who have done an excellent work as part of our @HorizonEU network over the last 3 years. Our @EMBO workshop starting today is a great opportunity to add a new dimension to their scientific careers.
#EMBOenhanceropathies
@MSCActions
Robin Andersson retweeted
Two training sessions on communication, led by @AlberichJorda , kick off our final event this afternoon.
See our program
EVENT VI ▶️bit.ly/3rPZQ59
Learn more about @enhpathy_H2020 ▶️ enhpathy.eu
@MSCActions
Robin Andersson retweeted
Histone inheritance is required for epigenome maintenance and early embryonic development! Out in @NatureGenet tinyurl.com/yc8bexr8 🎊💃. Thanks @AliceScientist, @BiranAlva, @NicoAlc82 & @albooo87 for heroic efforts 👏💪 & collaborators @josh_brickman, @robin_andersson . 🧵👇
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This will be my (academic) home during the fall. On a sabbatical at the Broad, kindly hosted by @kasper_lage and the @novonordiskfond center for genomic mechanisms of disease. Looking forward to lots of interactions and awesome science! Reach out if you want to meet up!
Super excited to share our study on the importance of proper epigenetic inheritance for cell identity and developmental competence, a fantastic collaboration with @groth_anja and @josh_brickman, led by @AliceScientist, @BiranAlva, @NicoAlc82, @albooo87 nature.com/articles/s41588-0…
Robin Andersson retweeted
As a student we were taught, “no experiments could show chromatin did more than salt,” but now with the amazing @groth_anja + @robin_andersson; @AliceScientist, @BiranAlva, @NicoAlc82 & @albooo87 show pluripotency required balanced epigenetic inheritance!
nature.com/articles/s41588-0…