Clinician-Scientist. PhD @CCRB27 @KingsCollegeLon. Former Resident Oral Path & Med. GlobalHealth @KingsThinkTank and former fellow @FlagshipPioneer
London
Joined March 2021
- Tweets33
- Following520
- Followers121
- Likes817
Rupali Lav retweeted
In autopsy of failed heart disease study, AstraZeneca $AZN raises broader questions about silencer drugs
STAT's @DrewQJoseph on the CARDIO-TTRansform data presented this morning at #ESC26
statnews.com/2026/08/28/astr…
$IONS $ALNY
Rupali Lav retweeted
Proud to be an investigator on this study! For many years now, I have taught our fellows that they can no longer just say KRAS mutant (need to specify variant). Now, this is the first for p53 Y220C today with more to come.
In a phase 1 study of the oral p53 reactivator rezatapopt in heavily pretreated patients with TP53 Y220C–mutated solid tumors, the most common adverse events were nausea and vomiting, and the overall response was 20%. Full PYNNACLE study results: nej.md/3OIQC5P
Science behind the Study: Restoring Function to a Variant of p53 in Solid Tumors nej.md/3N0pQW8
ALT Panel A: A figure showing the change in the sum of diameters of the target lesions across tumor types. Panel B: A figure showing the overall duration of treatment and the time to first response observed in 46 patients treated with a dose in the observed efficacious-dose range who had wild-type KRAS.
Calling all hard tissue researchers- Here’s a cool technique to study hard tissue development. Great work from @KrivanekLab and always a pleasure to collaborate with this team! @CCRB27
We are excited to share our new versatile technique "BEE-ST" that allows precise quantification of hard tissue (🦴and🦷) development and healing across species!
🐭🦎🐟🐸🐔
New in @ScienceMagazine
#ScienceAdvancesResearch
science.org/doi/10.1126/scia…
Thrilled to have part of my PhD work out in Stem Cell Reports. Thanks to @KrivanekLab for the fantastic collaborative effort, @NAnthwal for pushing this through its crucial final stages and to all of Tucker Lab and @CCRB27 for the constant support throughout this project.
Wnt signaling from Gli1-expressing apical stem/progenitor cells is essential for the coordination of tooth root development dlvr.it/Sl1KqN
Rupali Lav retweeted
Looking for an exciting dev bio opportunity London? Well, Prof Abbie Tucker's lab @CCRB27 is looking for two (yes two!) new members! And the best(/worst) thing is, you'll get to work with me! 1/4
Rupali Lav retweeted
Rupali Lav is Tucker Lab’s most recent PhD graduate. Her research focuses on unraveling the cellular and molecular mechanisms driving post-natal dental development and regeneration. Chat with her about life in the Himalayas, hiking, and the translation of bio-innovation.#MeetCCRB
Graduated today!Thank you to #TuckerLab and @CCRB27 for providing me ample opportunity to explore new ideas,learn, and grow from the peaks and valleys of scientific exploration. To my labmates, thanks for the support, friendship and laughs amidst perpetual crisis.@kingsdentistry
Rupali Lav retweeted
Tucker group is led by Prof Abigail Tucker, a developmental biologists who loves getting side-tracked by weird and wonderful creatures in the animal kingdom. Echidna, snake, opossum, bats. Chameleon eggs incubating in the lab as we speak. #MeetCCRB
Rupali Lav retweeted
#MeetCCRB: Tucker group is fascinated by the development of the head, with a focus on the jaw, teeth and ear. Formation of these structures involves complex interactions, and we are interested in how the various cells and tissues talk to each other to make a functioning organ.
All smiles today! Happy to share that I had an enjoyable and interesting discussion during my PhD viva and have passed with minor amendments. Thanks to Team Tucker, @CCRB27, and our collaborator Jan @KrivanekLab for constant support and insightful discussions.
Rupali Lav retweeted
Huge congratulations to #CCRB's Dr @heather_e_white and Dr @rupali_lav for both passing their vivas today! Big celebrations currently underway 🎉🥂🎓
This is a wonderful opportunity for women entrepreneurs in the King's network. I was part of the 2021 cohort and met a fantastic group of driven entrepreneurs. Apply now even if you're at the MVP stage!
📣Applications for the annual Women Entrepreneurs Retreat are open! There are only 50 spaces available, so get in quick to secure your place 🤩 👉🏽 bit.ly/3qgT58z 📍Bush House 🗓️22-24 April
Rupali Lav retweeted
Friends, I’d love to know what open questions you’re stoked about (esp. if you think a non-traditional organism or unique biology in a traditional one holds the key). Would concerted effort/tech advancement unlock? Want to know that too. Reply here & I may ping you to learn more!
Rupali Lav retweeted
We are delighted to announce that 11th edition of King’s Think Tank’s Annual Policy Journal, The Spectrum, is now published.
Read the 11th Edition of The Spectrum Today: bit.ly/3hOZpAS
Rupali Lav retweeted
My take on current situation: variants will continue to cause issues but our vaccines (both doses!) are effective as an additional layer of protection. We have to move away from harsh restrictions & lockdowns, to data-driven, precise outbreak management using science & logistics.
Rupali Lav retweeted
As we run up to the G7 Health Ministers meeting, check out this set of papers on how the UK can play a greater role in global health. Covers AMR, health tech, mental health and health security 👇 Amazing work and ideas from students @KingsThinkTank 👊
Our collaborative paper with @fh_research is out now! 📚
In this collection of papers we explore Britain's future as a leader in global health, post COVID-19 ⚕
Read it here: kingsthinktank.com/publicati…
Rupali Lav retweeted
Wonderful meeting with @R4RXResilience today on our upcoming Global Health collaborative paper with @fh_research!
Stay tuned for its' release!
@GursharanKhera @CoralieBelair @l_rupali @pedrarabiee Enya Khan @rcsloggett