Stefanie Krug (@steffikrug) header
Stefanie Krug (@steffikrug) profile picture

Postdoc in the Mitchell lab at UW Micro. Pathogenesis of infectious diseases, sports and food. Smile and the world smiles back at you!

Seattle, WA
Joined January 2011
Photo by Stefanie Krug (@steffikrug)Photo by Stefanie Krug (@steffikrug)Photo by Stefanie Krug (@steffikrug)Photo by Stefanie Krug (@steffikrug)Photo by Stefanie Krug (@steffikrug)
Stefanie Krug retweeted
NIH is not issuing awards. You may think that it's because they it is coming up with new directions of research...The apposite is true. Here is a graph showing how many fewer new funding opportunities that NIH has posted over time. -91%, a trend that started on Jan 2025.
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Stefanie Krug retweeted
I don't get Medicaid. I’m not on food stamps. I rely on no Social Safety nets. But I still believe in FULLY funding these programs. Why? Because I'm not a cruel ruthless selfish piece of shit.
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Stefanie Krug retweeted
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I’ll just leave this right here.
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A federal judge has issued a permanent injunction blocking the plan to cap NIH indirect costs at 15%. The judge highlighted that the policy would have caused “imminent risk of halting life-saving clinical trials” and “disrupting “innovative medical research and treatments”.
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🚨Excited to share our most recent publication on how navitoclax, a Bcl-2 inhibitor, enhances TB treatment by improving bacterial clearance and reducing lung damage. A promising step forward for host-directed therapies in TB. Read more: nature.com/articles/s41467-0…
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I can’t believe this needs to be said. TransGENIC mice are not TransGENDER mice
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I'm attending the #standupforscience2025 rally in Seattle tomorrow (Fri March 7th), 12-3 pm PST, Mural Amphitheatre at Seattle Center. There are similar protests and walk-outs scheduled across the country; find the one closest to you here: standupforscience2025.org/lo… . #scienceforall
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We are not taking Trump's unprecedented and shortsighted assault on science, research and education lying down. Here is what we're fighting for: standupforscience2025.org/ou…
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Stefanie Krug retweeted
Pitt to pause PhD admissions, following Vanderbilt and USC, because of uncertainty of NIH funding to academic universities. Who will teach and train US scientists for pharma and biotech? Should we import them from countries that do? wesa.fm/health-science-tech/…
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Stefanie Krug retweeted
CONSTITUTIONAL CRISIS: TRUMP DEFIES FEDERAL COURT ORDER 🚨 The Trump administration just told a federal judge that it will NOT comply with a court order to resume funding for USAID and State Department foreign assistance. Let that sink in—a sitting president is outright refusing to follow a federal court’s ruling. This isn’t just corruption. This is a constitutional crisis. The executive branch is defying the judiciary—a direct violation of the separation of powers. This is how dictatorships start: ignore the courts, consolidate power, rule by decree. What happens when he refuses to follow ANY ruling? What happens when the courts tell him to leave office, and he just says “No”? This is the moment we either defend democracy or lose it.
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Here’s a reason why the incoming NIH Director, health economist Jay Bhattacharya, should know cutting indirect costs at NIH is self-defeating and stupid. Every $1 invested by NIH returns $2.5. So $4B “savings” is actually $10B we lost. nih.gov/about-nih/what-we-do…
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Stefanie Krug retweeted
It seems few people know what an “indirect cost” is or why it has to be 40-60%. The reason the government forced universities to raise their indirect costs up to (typically) 40-60% was to force a huge amount of regulations on the universities while also minimizing the bookkeeping to comply with those regulations. This includes the work by contract managers, compliance lawyers, accountants, safety management, etc., who are required by the government per the terms of the contract. If universities had to allocate all those categories of labor to each contract hour-by-hour it would require too much bookkeeping, which would waste money. (I’m setting aside for now the question of whether or how much the regulations are wasting money and only discussing how you bookkeep the effort to comply with the regulations.) So to save money, while also requiring universities to do these types of work, the government requires universities to roll those categories of labor into “cost pools” that must be allocated as a percent of the technical work in each of the contracts. While the actual “overhead” might be only 15%, these pooled labor charges that are required by the government are typically much more. Second, the government doesn’t allow the universities to figure out their own indirect rates. These rates are determined by the federal government through audits every couple of years. The government then sends a document telling the university what rate to use for its cost pools. For example, the University of Colorado was told by the DHHS to use 54% (colorado.edu/controller/site…) and U. Nebraska was told by DHHS to use 55.5% (uofnelincoln.sharepoint.com/…). 40-60% is not only reasonable to fulfill the terms of the contract, it is the rate that the government tells the university it can charge for all the work the government requires the university to do. So if the government wants to reduce the indirect rate to 15%, then it needs to do one of these two things: Either (A) eliminate all the federal regulations that force the universities to do those categories of work (compliance, accounting, management, safety management, tracking harmful chemicals, etc.) Or, (B) stop requiring universities to pool those real costs into the “indirect cost” category and allow universities to include them in the “direct costs” of the contract. If the government chooses (A), then the safety rails have been entirely removed. (Even if the government lowers the regulations without entirely eliminating them, the costs they impose will still be real costs that probably come out to more than 15%.) Or, if it chooses (B), then the direct costs will go way up and research will actually be less efficient because all the bookkeeping, not more efficient. But if the government caps the indirect rate at 15% without doing either (A) or (B), then it will be impossible to do research for the federal government without going bankrupt. That’s the worst possible choice. It will kill research in the US. Is that what we want? I can explain it for you but I can’t understand it for you. It’s up to the reader not to be ignorant.
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Stefanie Krug retweeted
This is a list of blockbuster drugs in 2024. Guess how many can trace their origins to NIH funded research? All of them.
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Impact of NIH funding in Georgia: NIH AWARDS FUNDING: $780 M JOBS SUPPORTED: 11,816 ECONOMIC ACTIVITY SUPPORTED: $2.18 B Bio Industry Impact in the State: Jobs: 37,031 Businesses: 3,284 Cutting NIH indirects will kill jobs and cause a recession. unitedformedicalresearch.org…
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Stefanie Krug retweeted
I am not normally an alarmist, but these are not normal times. This change would cripple research infrastructure at hundreds of US institutions, and threatens to end our global superiority in scientific research. grants.nih.gov/grants/guide/…
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Replying to @AuschwitzMuseum
Never forget!!!
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This is one of the hardest but also one of the most important warnings from the history of Auschwitz coming to us today. In fact, perpetrators were people who accepted and followed an ideology that made them believe that they were better than others, an ideology that rationalized and promoted hatred and evil. This ideology became part of their everyday lives and environment. They were not monsters. They were people: fathers and mothers, husbands and wives, sons and daughters. They were farmers, doctors, bakers, bankers, architects, or carpenters. They had their family joys and problems, favorite desserts or songs, hobbies or fears. They were people like us. But they also perpetrated horrible, monstrous acts on behalf of the ideology they believed in. Dehumanizing all the „others” was a tool that helped them achieve their goal. The perpetrators thought of themselves as moral people. And this is the scary part of this history. We should not and cannot dehumanize them, as their story and choices are the human warning. For us all.
7 February 1979 | Josef Mengele, an SS camp doctor who made selections & perpetrated deadly pseudo-medical experiments on Auschwitz prisoners, died in Brasil. After the war, he fled to South America, where he evaded capture for the rest of his life. SS-Hauptsturmführer Josef Mengele was researching the issues of twins and the physiology and pathology of dwarfism in close cooperation with the Kaiser Wilhelm Institute of Anthropology, Genetics, and Eugenics in Berlin-Dahlem. He was also interested in the etiology and treatment of the gangrenous disease of the face, a little understood disease endemic to the Roma prisoners in Auschwitz. In the first phase of the experiments, pairs of twins and persons with inherited anomalies were put at the disposal of Dr. Mengele and subjected to all imaginable specialist medical examinations. They were also photographed, plaster casts were made of their jaws and teeth, and they were toe- and fingerprinted. As soon as these examinations were finished, they were killed with lethal injections of phenol to the heart so that the next phase of the experimentation could begin: autopsies and the comparative analysis of their internal organs. Listen to our podcast about the criminal medical experiments of Josef Mengele: youtu.be/M1OKQb1EPyw
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Stefanie Krug retweeted
In an unprecedented move, research-grant reviews have been suspended indefinitely at the world’s largest public funder of biomedical research go.nature.com/4gclXG0
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