Geneticist, co-founder at @VariantBio and @FiixSoftware, PhD @CSHL, postdoc @nygenome and @Columbia.
Seattle, WA
Joined July 2008
- Tweets1.2K
- Following643
- Followers978
- Likes1.7K
Stephane Castel retweeted
With co-author @stephanecastel of @VariantBio in front of our cover of @ScienceMagazine at ASHG @GeneticsSociety in Montreal. Come to their booth and get a free copy! Missing my co-senior author @KeoluFox.
Our study on Polynesian founder effects is on the cover of @ScienceMagazine! Led by @KeoluFox and @alexGioannidis with data from a @VariantBio study in French Polynesia, it finds founder effects 10x+ stronger than in Finland. Huge validation of our thesis, and much more to come!
Stephane Castel retweeted
Variant Bio leverages AI-powered Inference platform in an expanded collaboration with @Boehringer: medium.com/variantbio/expand…
Working with the BI team on kidney disease has been incredible and we couldn't be happier to expand our collaboration into cardiovascular disease. Our top priority at @VariantBio is getting discoveries from our platform and data into the clinic and this helps realize that goal.
Thrilled to announce our latest drug development collaboration! We are now expanding our existing partnership with @Boehringer into cardiovascular disease for a total potential deal value exceeding $250 mm: prnewswire.com/news-releases…
Thanks for the support, Josh! Our goal is to put insights from our work into the hands of partners who can help turn them into new treatments. Inference Agents are a big step in that direction.
1/ Big news today from Lux family co Variant Bio 🧬📈@VariantBio
Announced its new Inference platform is now available to research partners + has collaborations with several pharmaceutical companies in deals totaling more than $200 million including Boehringer + Novo Nordisk...
Honored for @VariantBio to have been featured by @SoftBank in their Sōzō Insights series.
“They’re solving the biggest bottleneck that exists in drug discovery.” -- John Xue, SoftBank Investment Advisers (for more, read the recent Sōzō Insights feature piece highlighting Variant Bio's unique approach to drug discovery): visionfund.com/insights/vari…
Our SABR manuscript is out in Nature Genetics. SABR is the largest functional genomics dataset from a continental African cohort. We mapped the genetic architecture of blood expression, splicing, and cell types in over 600 individuals from 3 SEB groups.
nature.com/articles/s41588-0…
Summary stats are public; individual-level WGS/RNA-seq data available via controlled access on the EGA. If it’s useful for your research, apply. We want it to have broad impact! github.com/variant-bio/SABR
Stephane Castel retweeted
Variant Bio visits long-term partners in the Faroe Islands to celebrate the end of participant recruitment and kick off data generation together: medium.com/variantbio/celebr…
Stephane Castel retweeted
Listen to Seattle's NPR coverage of Variant Bio's new partnership with Novo Nordisk and our approach to making human genomic research and drug discovery both more ethical and equitable: kuow.org/stories/seattle-bio…
I will be at #JPM25 next week - don't hesitate to reach out if you'd like to connect. Looking forward to an exciting week!
Stephane Castel retweeted
Our advisor @KeoluFox sharing news of Variant Bio's ground-breaking partnership with Novo Nordisk during a keynote at the Pacific Symposium on Biocomputing (PSB) 2025 in Hawaii this week
The collaboration between @VariantBio and @novonordisk will trigger our long term benefit sharing program for the first time! Read about it in the NYT. nytimes.com/2025/01/07/healt…
Excited to share that @VariantBio is partnering with @novonordisk to identify metabolic disease targets. This gives us the opportunity to translate more findings into treatments that will have a real world impact for patients. medium.com/variantbio/varian…
Stephane Castel retweeted
How Variant Bio and the Pukapuka Community Group returned group-level results from a collaborative genomic research study in Auckland: medium.com/variantbio/return…
Stephane Castel retweeted
We recently met with partners and community leaders in New Caledonia to conclude one of Variant Bio’s largest studies to date: medium.com/variantbio/conclu…
Stephane Castel retweeted
Congratulations to Olivia Gray from Variant Bio and all of our colleagues who received an abstract award @GeneticsSociety last week! #ASHG2024
Stephane Castel retweeted
Last week, Sarah LeBaron von Baeyer from @VariantBio gave a plenary talk at the BIO2024 Conference at the @UPTuks Future Africa campus in Pretoria, South Africa based on our recent Commentary in Cell. In case you missed it, read the full publication here: sciencedirect.com/science/ar…
Stephane Castel retweeted
How Variant Bio is leveraging multi-omics data from studies with diverse populations to boost drug discovery and development: medium.com/variantbio/the-po…
