@thali_lab

Official Twitter home for the Thali lab at the University of Vermont, USA.

 Burlington, VT
med.uvm.edu/mmg/faculty/markus-thali-ph-d
Joined March 2016
  • Tweets41
  • Following120
  • Followers121
5Media
Thali Lab retweeted
Gary Ward@GEWard146 Mar 2023
Interested in doing a postdoc exploring the cell biology & biophysics of Toxoplasma motility/host cell invasion? Join us in the Ward lab! Send cover letter and CV to Gary Ward: see wardlab.us for contact details and more information about who we are and what we do.
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Our new preprint on Migrate3D is online! Huge thanks to first author @MatthewKinahan1 and our gracious lab home @thali_lab. Thread follows explaining what this is all about:
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It's official! I will be starting a research group at SUNY Upstate Medical University this fall. I am overwhelmed with gratitude for my past and present scientific mentors and friends who have made this so fun and helped make me a better scientist 1/3
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Thali Lab retweeted
CMB @ UVM@uvmcmb17 Aug 2021
Congratulations to CMB student Emily Whitaker who successfully defended her dissertation titled, "Analysis of Host Factors Involved in Regulating HIV-1-Induced Syncytium Formation." 👏👏👏
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Thali lab alumnus @DKrementsov's latest and greatest!
Dimitry Krementsov@DKrementsov21 Oct 2020
Our host genetics-microbiome EAE paper is finally out at PNAS! pnas.org/content/early/2020/…

Interactions between host genetics and gut microbiota determine susceptibility to CNS autoimmunity...

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system. The etiology of MS is multifactorial, with disease risk determined ...

pnas.org
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Thali lab alum Nate Roy's latest masterpiece!
Nathan Roy@roybiolab9 Sep 2020
Finally out! Big thanks to all of our amazing collaborators and to @J_Cell_Sci for a fast, fair review process in these unprecedented times.
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1/n Our work describing the adaptation of the CDC RT-qPCR assay for use with alternative Qiagen RNA extraction kits, as well as skipping the RNA extraction step entirely is live on bioRxiv. Pls retweet. #coronavirus #COVID19 #StayAtHome biorxiv.org/content/10.1101/…
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Tight uropod-to-uropod contact between two isolated syncytia. Could one of them have fusion-replenished surface CD4? (~25% of syncytia have surface CD4!) ...is this a VS? from @msymeonides, also independently observed by our grad student Emily Whitaker!
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Immunomagnetically-isolated syncytium trying to decide which way to go. from @msymeonides
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Immunomagnetically-isolated HIV-induced T cell syncytia, an assay 15 months in the making and nearly ready for prime time! Isolation made possible by surface-expressed split-GFP in donors/targets and a whole-GFP-specific nanobody @ChromoTekGmbH @STEMCELLTech. by @msymeonides
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Thali lab alum Nathan Roy's latest work in preprint!
Dr. Janis Burkhardt@BurkhardtLab26 Nov 2019
New work from @Roybiolab in collaboration with the Karimi lab just out on BioRxiv. Its true - CrkL is not Crk-like. Now we know which Crk isoform to target for immunotherapy. biorxiv.org/content/10.1101/…
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Accepted for publication in @VirusesMDPI!
Thali Lab@thali_lab25 Oct 2019
Our EWI-2 preprint is now on its 4th version on @biorxivpreprint - lots of new data (and authors!) added, and currently under peer review. The new Figure 6 is a great teaser of the direction we're now headed... HIV-induced syncytia are pretty special! biorxiv.org/content/10.1101/…

EWI-2 Inhibits Cell-Cell Fusion at the HIV-1 Virological Presynapse

Cell-to-cell transfer of virus particles at the Env-dependent virological synapse (VS) is a highly efficient mode of HIV-1 transmission. While cell-cell fusion could be triggered at the VS, leading...

biorxiv.org
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I’m happy to share this work on how cell fusion promote a cell differentiated state through plasma membrane remodeling and changes in bioenergetics. “Transcriptional reprogramming in fused cells is triggered by plasma-membrane diminution biorxiv.org/content/10.1101/…

Transcriptional reprogramming in fused cells is triggered by plasma-membrane diminution

Developing cells divide and differentiate, and in many tissues, such as bone, muscle, and placenta, cells fuse acquiring specialized functions. While it is known that fused-cells are differentiated,...

biorxiv.org
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Our EWI-2 preprint is now on its 4th version on @biorxivpreprint - lots of new data (and authors!) added, and currently under peer review. The new Figure 6 is a great teaser of the direction we're now headed... HIV-induced syncytia are pretty special! biorxiv.org/content/10.1101/…

EWI-2 Inhibits Cell-Cell Fusion at the HIV-1 Virological Presynapse

Cell-to-cell transfer of virus particles at the Env-dependent virological synapse (VS) is a highly efficient mode of HIV-1 transmission. While cell-cell fusion could be triggered at the VS, leading...

biorxiv.org
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Yes please!
Proteintech Group@Proteintech16 Aug 2019
Keep your antibodies cool and safe with a Proteintech Benchtop Cooler. ❄️ Keeps vials at 0˚C or below on lab bench. ❄️ Insulating refrigerant chills samples quickly. ❄️ Interlocking feature means they can be joined. RT and we will send one to your lab 😎 #phdchat #antibodies
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Thali Lab retweeted
CMB @ UVM@uvmcmb17 Apr 2019
Emily Whitaker is ready to share her own #UVMresearch with you!
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Very much looking forward to sharing our data at the UVM Microbiology and Molecular Genetics seminar series on Wednesday #uvm #mmg #vermont #vzv #glycoproteins #structure #drslo instagram.com/p/BuVEkvHHBXw/…

Stefan Oliver (@stefan.oliver) • Instagram photo

instagram.com
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Yes folks! The moment we’ve all been waiting for: Sean McCauley’s thesis project is now live to the world. Congratulations to Sean and his whole #DendriticCell clan @UMassMedical @UMass @GSBS_UMassMed @UMassMedRTI #HIV nature.com/articles/s41467-0…
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