Neurologist (MD, DPhil, MRCP, FEBN) - in love with AD research - Senior Research Fellow in Cognitive Neurology at the University of Oxford
Oxford, England
Joined January 2020
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Digital testing is increasingly used in Alzheimer's Disease. There are plenty of platforms out there, but very few can be administered fully online, are patient friendly and validated against AD biomarkers. Check out Sijia's Zhao amazing platform - OCTAL! ncbi.nlm.nih.gov/pmc/article…
Amazing discovery of new hybrid cells that lie between neurons and astrocytes - likely to be key players for hyperexcitability in the CNS, with potential implications for AD. Check out the article in Nature! nature.com/articles/s41586-0…
What a week! Thanks #AAIC2023 for the great science and very inspiring talks - including new criteria for AD, exciting results from the phase 3 Donanemab trial, and new developments in the fields of plasma biomarkers and digital tools!
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For anyone wondering why feels like November again, I was listening to the BBC yesterday, and couldn't stop thinking: this sentence is really tragicomic.
Exciting talks coming up at the #BrainConf22! Ditch what you were planning to do on the 24th and 25th of February and join us - as interesting and fun as a conference gets!
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Want to know whether some brain areas are more vulnerable than others to SARS-Cov2 infection? Check out this point of view from members of the EAN cognitive panel! doi: 10.3233/JAD-210008 @EANeurology @Dr_Di_Lorenzo @scarioni_marta
Want to know more about the biological links between Alzheimer's Disease and Epilepsy, and how to measure and treat brain hyperexcitability in vivo? Check out our new paper!
Acedia rather than apathy? Lockdown has impacted greatly on mental health of healthy people and patients, but it would be a mistake considering their struggle as 'a-pathos', without feeling. Acedia is the 'noon demon', the torment monks felt when lacking drive in isolation
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True story. Patient: 'By the way doctor, your English is superb!' - my Ego reaches the ceiling - 'Well, is actually better than my Italian, no problemo, gracias! - my Ego sinking immediately. At least I've reached the phase when if they take a guess they say France or Sweden.
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Our new review on the impact of lacosamide on mood disorders in adult patients with epilepsy is online today! Always consider AEDs mood side effects in this patient population - huge impact on therapy adherence!
authors.elsevier.com/a/1bD4e…
m.youtube.com/watch?v=cYf-xN… In this moment of social racial unrest,very good overview of important genetics concepts for dismantling white supremacists bullshits, such as genetic isopoint, where if we go back in time we actually come from the same ancestors (skip the first 10m intro)
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Still too many people in streets and parks here in London behaving like nothing is going on: be smart guys! I promise no one is going to think you are less cool if you do, and you'll be wiser for sure!
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Amazing talk from Prof Scheltens on the current complexity of diagnosis and treatment in AD at #S4j- combined with exciting new hopes!
