Husband, father, virologist, pharmacist, soccer player, and chess enthusiast 🦠🧬😷 🥼 🔬⚽♞ Working on HBV and SARS-CoV-2 @TheOttLab @GladstoneInst
San Francisco, CA
Joined September 2020
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Taha Y. Taha retweeted
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What could we discover if we had a binder for every protein in the human proteome?
We are excited to introduce the Bindome, an open and free resource of over 300,000 designed protein binder candidates against over 8,000 human target proteins.
🧵
Taha Y. Taha retweeted
Announcing Built with Claude: Life Sciences, a global virtual hackathon.
Join us and @GladstoneInst for a week of researching and building with Claude Science and Claude Code, with a prize pool of $100k in credits.
ALT Event card for Built with Claude: Life Sciences, a global virtual hackathon, July 7–13, with the Gladstone Institutes logo and a screenshot of Claude Science.
Taha Y. Taha retweeted
Today we report single-cell APEX-seq (scAPEX-seq) — a new method for unbiased mapping of *subcellular* transcriptomes at single-cell resolution. This approach reveals cell states that are not detectable by standard scRNA-seq, and enabled us to identify regulators of CAR T function that improve solid tumor killing.
biorxiv.org/cgi/content/shor…
Taha Y. Taha retweeted
Just posted a preprint on a huge new single-cell study of Parkinson’s and its application to understanding noncoding variation. 🧵below. Led by Shreya Menon and Adam Turner and in collab w/ GP2 (@ASAP_Research), @BelloyMichael, @ZihHuaFang and others. doi.org/10.64898/2026.03.05.…
Taha Y. Taha retweeted
The first time you start a research lab, there’s no manual.
So I made one.
A practical toolkit for postdocs and early-career faculty launching their first lab: hiring, startup planning, collaborations, and building a sustainable research program.
zenodo.org/records/18883545
Taha Y. Taha retweeted
1) We have a new preprint paper out about population immunity to H5N1 and H5N5. Results are in line with what others have seen but there are two new findings. medrxiv.org/content/10.64898…
Taha Y. Taha retweeted
Thrilled to share the first major preprint from the lab. Viruses are classically viewed as targets of host sensing. Do viruses also sense and respond to the host? We propose viruses may act as “biosensors” of the host signaling state. A thread👇🏾
biorxiv.org/content/10.1101/…
Taha Y. Taha retweeted
SARS-CoV-2 continue to surprise us with evolutionary jumps. In this pre-print, we describe the Identification and genomic characterisation of BA.3.2: a highly divergent BA.3-related SARS-CoV-2 lineage from southern Africa. A thread 🧵 medrxiv.org/content/10.64898…
Taha Y. Taha retweeted
Excited to share our new work on immune aging! We explored whether the liver could serve as a temporary "factory" to produce immune factors that decline with aging, potentially helping to rejuvenate aged immunity. @mircoscopy.
Taha Y. Taha retweeted
Today in @Nature, in work led by @aditimerch, we report the ability to prompt Evo to generate functional de novo genes.
You shall know a gene by the company it keeps! 1/n
Taha Y. Taha retweeted
Today in @Nature we report a new prime editing strategy that can rescue a common cause of many genetic diseases in a disease-agnostic manner. This approach converts a redundant endogenous tRNA into an optimized suppressor tRNA, enabling a single prime edit to rescue premature stop codons across different diseases.
(1/15)
drive.google.com/file/d/1bSv…
Taha Y. Taha retweeted
So awesome to have this great paper from @SamReffsin and Sara Cherry out! In it, we use retrospective clone tracing to show that there are particular single cell states that are more susceptible to viral infection (both SARS-CoV-2 and flu)!
cell.com/cell/fulltext/S0092…
Taha Y. Taha retweeted
Nature research paper: Convergent genome evolution shaped the emergence of terrestrial animals
go.nature.com/4qX6KiM
Taha Y. Taha retweeted
Excited to share @Nature: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein (wt) structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation. 🧵
nature.com/articles/s41586-0…
Taha Y. Taha retweeted
Danya was a Chess Life magazine columnist from 2014 through 2020, writing a monthly column on endgames.
Now, all of his columns can be downloaded as one .pdf file here (no US Chess membership required):
uscf1-nyc1.aodhosting.com/CL…
US Chess is saddened to learn that GM Daniel Naroditsky has died. Naroditsky was a World Youth and U.S. Junior champion, and also a beloved educator, streamer, Chess Life columnist, and part of the @CLTchesscenter community.
📷 Lennart Ootes/@STLChessClub
new.uschess.org/news/gm-dani…
