Valeria Faccenda retweeted
📢 Join the free OPTIMIZE-RT online course on CBCT optimisation in Radiotherapy!
🤝 Learn, collaborate and implement change in your department.
🔗docs.google.com/forms/d/e/1F…
#OptimizeRT #Radiotherapy #EuropeanProject
Valeria Faccenda retweeted
Across 3 prospective studies, the signal for post-prostatectomy SBRT in 5 fx is increasingly consistent: feasible, low toxicity & excellent in-field control. StereoBed randomized data show no PRO/toxicity penalty; POPART/esSBRT show few local failures.
#ASTRO26 @rtdess @HimanshuNagarMD @RadOncDocJ @NRGonc @ASTRO_org @urotoday @ChadTangMD @TylerSbrt @SbrtSean @jryckman3 @seanmmcbride
Valeria Faccenda retweeted
So proud of our #POPART around the 🌍 superbly presented by @PanizzaDenis 👏🏼
@StAr_MCM74 @valefacc22 @CChissotti @CiroFranzese1 @Raffa_Lucchini @roberta_muni
Post-prostatectomy RT in just 5 fractions? 👀
Ferrario et al and POPART team reports 100 pts treated with prostate-bed SBRT (32.5 Gy/5 fx):
• Late ≥G2 GU toxicity: 8.5%
• Only 1 late G2 GI event
• Just 3 in-field relapses
• 30-mo biochemical control: 74%
Very encouraging local control and toxicity—but urinary QoL remains important to watch.
#ASTRO26 #ProstateCancer #SBRT @HimanshuNagarMD @rtdess @RadOncDocJ @angela_jia_ @urotoday @TylerSbrt
Valeria Faccenda retweeted
And PACE-POSTOP coming: (66/33 or 52.5/20) va 32.5/5
Should be open early 2027…
Replying to @lauren_henke
SO, the GU-003 data could continue to look worse with time as f/u matures, because of the DOSE ESCALATION. 📉 These data don’t kill hypofrac, they just strengthen the case for 52.5 Gy/20 fx, as used in RADICALS, to be preferred hypofrac postop regimen—shorter tx **without the dose escalation** used in GU003. #ASTRO26 #ProstateCancer
#ASTRO26 #Pcsm #RadOnc
Valeria Faccenda retweeted
🚨 New publication! 3-fx SBRT (30Gy) with real-time US tracking for localized #PCa: safe, well tolerated, low severe side effects, preserved QoL & encouraging early BRFS results (98.2% at 12mo)
Huge congrats 👏🏼 @matteo_mom64240 & Ilenia on their 1️⃣paper!
mdpi.com/2072-6694/18/18/295…
Valeria Faccenda retweeted
“How to’ do SBRT in prostate cancer” consensus recommendations is to define minimum requirements, common practices and additional options for prostate SBRT based on scientific evidence, expert opinion and consensus. @RO_GreenJournal @ESTRO_RT
Read it 👉 thegreenjournal.com/article/…
Valeria Faccenda retweeted
Congrats on this work and publication @ZilliThomas ! Yours and @StAr_MCM74 show good tolerance with short to medium term FU.
Maybe less hypoxia with SBRT will show that SBRT x1 is equally effective as SBRT x5.
But need to do RCT. What would be your primary outcome?
Single-Fraction Stereotactic Body Radiotherapy for Localized Prostate Cancer jamanetwork.com/journals/jam… @Mat_Guc @CiroFranzese1 @alongi_filippo @Achard_Verane
Valeria Faccenda retweeted
📢 SAVE THE DATE
Optimisation of CBCT Imaging in Radiotherapy
🗓️ 16 October 2026
📍 Monza, Italy
✅ Free registration
🌍 Training in English for ROs, MPs & RTTs
More details coming soon!
#OptimizeRT #Radiotherapy #EuropeanProject
Valeria Faccenda retweeted
Single-fraction SBRT for localized prostate cancer continues to push the boundaries.
Multicenter phase 1/2 trial (45 pts), single 19-Gy fraction:
✅ 3-year bRFS: 92.9%
✅ Grade 2+ GU AE: <10%
✅ Grade 2+ GI AE: <5%
⏳ Deadline 1 June! Help map CBCT imaging practices across Europe for the #OPTIMIZE-RT project.
Calling all European #RTTs, #MedPhys, #Oncologists & #QualityManagers.
👉 Join here: bit.ly/4u9i9fT
#Radiotherapy #Radonc #PatientSafety
Valeria Faccenda retweeted
Great debate @ESTRO_RT - do we need augmented/adaptive radiotherapy for prostate cancer? @CZamboglou @DrAndrewLoblaw @valefacc22 and Adam
Mitchell @royalmarsdenNHS Good points made by both sides, but if we can do better, surely we should?
🧠 Fusion uncertainty is real...even “perfect” expert fusions can differ.
Quantifying operator variability is key to define a probabilistic GS and benchmarking automatic registration vs human performance 🧮
@EFOMP_org @fisica_medica #SRS #automatism
👉🏻physicamedica.com/article/S1…
Valeria Faccenda retweeted
🔍Check out a post-hoc analysis of the ABRUPT trial on the 🔗between ☢️ RT dose to pelvic substructures & late GU TOX
⛔️ bladder trigone D1cc ≥20.3 Gy
⛔️ NVB D0.035 cc ≥23.6 Gy
➡️doi.org/10.1016/j.ctro.2026.…
#prostatecancer @OncoAlert @oncodaily @urotoday
Valeria Faccenda retweeted
🙏 Huge credit to all speakers, moderators and colleagues who made the 1️⃣#prostateSBRTMonza 🇮🇹Symposium a great success🤩
#ProstateCancer
@ESTRO_RT @ISRSy
@airo_young
🚀 Join us for the 1st symposium on prostate SBRT. Medical physicists are welcome too!
📅 5–6 February 2026
📍 Hotel de la Ville, Monza
🔗 tinyurl.com/sbrt2026
Don’t miss this chance to learn and discuss with experts in the field.
@ESTRO_RT @ISRSy @fisica_medica @AIRO
🧨 Join us for #PCa #SBRT Symposium by @StAr_MCM74 & @PanizzaDenis with 🔝tier international faculty @piet_ost @CDraulans @CZamboglou and 🌟Italian RadOncs together with @ESTRO_RT President @BarbaraJereczek
🔗Registrations open—limited seats
tinyurl.com/sbrt2026
@valefacc22
Valeria Faccenda retweeted
💥 #AIRO2025: 3 days of updates in cutting-edge treatments… yet the best one is still us❗️💪🏻
#radonc
@unimib @AIROyoung
Valeria Faccenda retweeted
📢 NRGGU005 Phase III: 698 pts with intermediate-risk #ProstateCancer RCT; SBRT (n=353) vs M-IMRT (n=345)
✅ SBRT → better bowel HRQOL (MCID 35% vs 44%, p=0.03)
⚖️No diff in urinary HRQOL; EPIC continence favours SBRT
❌futile for DFS; IMRT had ⬇️3-yr biochemical failure (4.2% vs 7.8%)
SBRT safe, better QoL, ⁉️but not superior for DFS #ASTRO25 #RadOnc #PCSM
Valeria Faccenda retweeted
#astro25
@NRGonc Rtog 0924 trial on 2500 patients testing whole pelvic RT.
Negative trial
-OS no difference
-PCSM no difference
-DM no difference
-BCR was not SS different with only 4% difference at 10 years.
-toxicity increased
3 cooperative group trials now negative: getug01, Rtog 9413, Rtog 0924.
Goodbye WPRT











































