Scientist by day, random tinkerer by night
Joined June 2011
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We are thrilled that an article describing our #MINTplatform has just been published in @NatureBiotech!: nature.com/articles/s41587-0…
We're excited to share the latest improvements to our #MINTplatform
🧬🚀 We’ve made substantial progress in development of our modular integrase, or MINT, platform- a gene editing method that we believe will enable large-scale genome engineering. Our updated manuscript which showcases these advances is available on bioRxiv bit.ly/41Y14ud
I’m excited to be attending #ASGCT2025 to describe our latest progress on the #MINTplatform. I look forward to catching up with everyone at the conference!
We’re proud to share that all our abstracts were accepted to #ASGCT2025 —including three oral presentations, with our prion data selected for the prestigious #PresidentialSymposium. Click here to learn more: bit.ly/4jQF4ro #ASGCT #genomicmedicine #neurology #Innovation
My wife’s grandmother suffered from Alzheimer’s disease so it’s great that we are now working with Genentech to develop potential treatments for these types of terrible diseases.
Today we are excited to announce a global epigenetic regulation and capsid delivery license agreement with @genentech to develop novel genomic medicines for neurodegenerative diseases. Learn more here: bit.ly/4fwrN69
I’m heading to the @FASEBorg #GENESRC conference tomorrow to give a talk about our new #MINTplatform and I look forward to seeing former colleagues I haven’t seen in far too long!
Jeff Miller retweeted
One of our lead scientists, @wraithnot is presenting @FASEBorg about our exciting Modular Integrase (MINT) platform, a new approach to 🎯 integration of large 🧬 constructs into precise locations within the human genome. #genomicmedicine #MINTplatform
Our #MINTplatform does not use #CRISPR, #ZincFinger or #TALeffector to 🎯 DNA. Instead, we directly reprogram Bxb1 integrase to go where we want in the human genome. The details are in our @bioRxiv paper: bit.ly/3wwPLwy
Jeff Miller retweeted
We are thrilled to announce the publication of our manuscript detailing the development of our Modular Integrase (MINT) platform #MINTplatform is now live on @bioRxiv! bit.ly/3wwPLwy @f_fauser @gdavis624 @arangundy @wraithnot
Systematic Development of Reprogrammed Modular Integrases Enables Precise Genomic Integration of Large DNA Sequences biorxiv.org/content/10.1101/… - our paper describing reprogrammed serine integrases is now on BioRxiv!
Jeff Miller retweeted
We are excited to announce next-generation Modular Integrase (MINT) technology, engineered to enable large-scale genome editing. The MINT platform is a versatile, protein-guided genome editing method designed to integrate large sequences of 🧬bit.ly/44GSRe4
