Joined July 2019
APOE4 transforms healthy pericytes into scar-forming myofibroblasts and cripples the brain’s waste clearance. Fortunately, the vascular damage this causes is biologically reversible. Read the paper: DOI: 10.1016/j.cell.2026.08.058
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High sugar intake—even from seemingly 'healthy' sources like fruit juices—significantly increases your risk of cognitive decline. That’s why KetoFLEX 12/3 is foundational to the ReCODE Protocol. Protect your brain by restoring metabolic flexibility. eatingwell.com/sugar-dementi…
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A new study has found that binge-watching TV “very often” in midlife is associated with reduced brain volume. The damage can lead to dementia, stroke, cognitive decline, and more. healthline.com/health-news/b…
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Want to increase strength? You may want to cultivate your microbiome first. Older adults with the bacterium Roseburia inulinivorans had 29% greater grip strength and better VO2, leg press, and bench press scores. sciencedaily.com/releases/20…
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"I didn't remember my phone number." An 82 yr old is walking Land's End to London. Last year Dr Judy Benjamin walked over 2,800 miles across the U.S and said she was diagnosed with Alzheimer's aged 67 but recovered cognition after addressing factors contributing to her decline.
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Medical acceptance, even for simple solutions, can take more than 30 years. Unfortunately, our brains can’t wait, but the good news is that there is now so much that can be done to prevent and reverse cognitive decline. Take the Cq assessment: apollohealthco.com/know-your…
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Today, we’re going to continue talking about Dr. Bredesen’s Subtypes of Alzheimer’s. Yes, like we established in our last video on this, Alzheimer’s is not just one single disease. Every neurologist will tell you that no two Alzheimer’s patients that walk through their office present in their symptoms in the same way. Standard of care has largely relegated this to be a phenomenon with no real explanation, deciding to hyperfocus on Amyloid plaques and Tau tangles as the ”cause” for Alzheimer’s symptoms without asking the key question: Yeah, but: “What is driving the production of Amyloid and Tau, as well as the cognitive downsizing, in the first place?” Dr. Bredesen found that there were a variety of root cause triggers upstream that were driving the ensuing cognitive decline downstream. And if an effective treatment program were to be created and implemented for the prevention and reversal of the cognitive decline associated with Alzheimer’s, like, say, the ReCODE Protocol, it would be supremely helpful to start profiling specific subgroups of patients in order to personalize therapeutic approaches for greater efficacy. This is why the first step of the ReCODE Protocol is the Cognoscopy: Dr. Bredesen’s diagnostic framework for screening all the potential contributors and risk factors for cognitive decline. All of these tests and lab results paint a clear picture of where a patient stands and helps identify how they got there. It's the foundation for an individualized protocol to be built out for prevention or reversal. Over the years, Dr. Bredesen’s team has identified at least 36 contributors to cognitive decline. And most people who have already been diagnosed with Alzheimer’s disease or mild cognitive impairment turn out to have between 10 and 25 contributors to their cognitive decline. Reversing these contributors has proven effective in improving cognition and overall health and function. By 2017, Dr. Bredesen had found that his patients were falling into about 4 different buckets of slightly different Alzheimer’s. It wasn’t just one blanket diagnosis for everybody that one “silver bullet” drug could cure. Fast forward to today, in 2026, Dr. Bredesen’s team has found this list of subtypes expanding from four to six. On the last couple episodes we talked about Type 1 and Type 2 Alzheimer’s or “Inflammatory” and “Atrophic” Alzheimer’s . Now we’ll get into Type 3. Type 3 is: Toxic Okay, what does “toxic” mean? youtube.com/watch?v=OoOIkYVi… Please share with anyone you think this information can help. @DrDaleBredesen @ApolloHealthCo #alzheimers #alzheimersreversal #bredesenprotocol #alzheimersprevention #toxins #heavymetals #mycotoxins #dementia #MCI
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Strength Training, already a recommendation of the Bredesen Protocol, was found in new research to reduce the risk of death from neurological and cardiovascular disease, with just 2 hours per week being enough for a profound effect. bbc.com/news/articles/c0r2le…
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Protecting your brain from dementia doesn’t have to be difficult. As I described in The Ageless Brain, and now supported by new research, trying a variety of physically and intellectually stimulating activities can keep our brains healthy for longer. alzinfo.org/articles/prevent…
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Looking for a new hobby? A recent study has shown that bird-watching may keep your brain young. Bird-watching strengthens the areas of the brain that deal with memory, visual processing, and attention, which can help keep your brain stronger for longer. smithsonianmag.com/smart-new…
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“Mentally passive” screen time during sedentary activities can increase your risk of dementia. Replacing that time with mentally stimulating activities can reduce your risk by 7%, or 11% if physical activity is included. cnn.com/2026/04/06/health/me…
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According to a new longitudinal study, higher tau burden levels cause faster cognitive decline in women than in men. However, both men and women should know their p-tau 217 levels if they are over 35. auntminnie.com/clinical-news…
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Congratulations to Kerry Rutland, Dr. Neil Nathan, and Dr. Chi Kim on their landmark publication documenting the first example of reversal of cognitive decline in PCA (posterior cortical atrophy). mdpi.com/2673-8937/6/2/20
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Movement is a pillar of the ReCODE Protocol for protecting your brain health. As @EverydayHealth highlights, a sedentary lifestyle reduces blood flow to the brain, contributes to poor heart health, reduces neuroplasticity, and more. eatingwell.com/experts-warn-…
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youtube.com/watch?v=nRofm93X… This Fasting and Exercise Approach Helped Them Reverse Alzheimer's in this Trial | Dr. Kat Toups @DrDaleBredesen @ApolloHealthCo #alzheimers #alzheimersreversal #bredesenprotocol #alzheimersprevention
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Thank you to Dr. Jeffrey Bland and his remarkable team for the superb PLMI Clinical Mastery Conference in Chicago this weekend. Let’s all keep working to reduce the global burden of neurodegenerative disease—this is such a time of progress!
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The country's first "dementia village" is in development. This model will look more like a residential neighborhood than a retirement home, but I hope they will focus on improving health outcomes instead of just accommodating cognitive decline. people.com/dementia-village-…
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Dementia may show non-cognitive symptoms \ before your memory starts to decline, just as Parkinson’s may show harbingers before motor symptoms. The team at @HuffPost compiled a list of six common physical symptoms to look for. huffpost.com/entry/physical-…
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