Bäckhed Lab takes a translational research approach to investigate how the gut microbiota contributes to cardiometabolic disease.

Gothenburg, Sweden
Joined August 2020
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Excited and grateful to be part of this @novonordiskfond sponsored initiative to investigate if the gut microbiome causes cardiometabolic disease in humans!
By adding bacteria to our gut, removing them, or changing what we eat, we could reduce our risk of developing diseases such as obesity, type 2 diabetes, and cardiovascular disease. A new research project, led by @foodDTUdk at @DTUtweet and funded by the Novo Nordisk Foundation, aims to find out more about this link, ultimately leading to new prevention or treatment options for people living with, or at risk of, cardiometabolic disease. novonordiskfonden.dk/en/news… #obesity #diabetes #cardiovasculardisease
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In collaboration with @DanielJDrucker we made the surprising observation 10+ years ago that GLP-1R deficient mice dies. Further work led by @GreinerTU with support from @MucinBiology revealed involvement of #gobletcells.
More essential roles for GLP-1R in the mouse gut, here in the maintenance of colonic physiology and survival during energy deprivation in germ free mice @BackhedLab @MolMetab sciencedirect.com/science/ar…
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Replying to @TonyWu1985
Congratulations Tony and team. Great paper from a great scientist #proudmentor
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Ending the fall semester celebrating two excellent PhD defenses from Wilhelm Sjöland and Jamie Kraft @kraftyjamie . So proud of both of you - good luck with your future careers!
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Replying to @Filip_Knop
Congratz- good luck!
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Fantastic story - congratz to everyone involved!
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⁦@YolsanzSanz⁩ provides a great overview of our paper just poulished in ⁦@Nature⁩ nature.com/articles/d41586-0…
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Replying to @BrodinPetter
Thanks Petter!
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Following oxygen adaptation of F. prausnitzii, which allowed production of live bacteria products, we could in collaboration with @LorentzoM demonstrate that the combination is safe for human consumption that will allow further intervention studies.
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Great collaboration spearheaded by @antoniomol83 and @NemetGroup together with @pierrebellassen, @Rimachaka, @ClementLab, Hazen lab and many more #metacardis
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Our paper Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality is available online sciencedirect.com/science/ar… in @JACCJournals #imidazolepropionate #microbiota #HeartFailure
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Humbled and excited to have been selected for funding by @ERC_Research for the project IMPACT. In IMPACT we will investigate how microbially produced imidazole propionate contributes to NASH and heart failure #ERCAdG @uniofgothenburg
🎉 Congratulations to the 218 new ERC Advanced Grant recipients 🏅! Want to know who they are and where they intend to work? Full list 👉 bit.ly/ERC2022AdGwinners [#thread 2/4]
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