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Bishai Lab

@BishaiLab

Our team studies @Mycobacterium @tuberculosis as a probe to understand fundamental cell biology and immune defense mechanisms. @HopkinsMedicine @TBCenterJHU

 Baltimore, USA
bishailab.org/
Joined March 2020
  • Tweets72
  • Following204
  • Followers724
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Photo by Bishai Lab (@BishaiLab)Photo by Bishai Lab (@BishaiLab)
Our latest paper in @NatureComms demonstrates dual antibacterial and immunomodulatory activities of a novel glutamine metabolism inhibitor. The study was spearheaded by a terrific postdoc @Sadiyarsh who is also on the academic job market. nature.com/articles/s41467-0…
Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against...

Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against...

Nature Communications - Parveen et al., using immunological, and metabolomics-based assays, demonstrate the importance of host glutamine metabolism in tuberculosis pathogenesis and show...

nature.com
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Job alert!! Parveen lab will be recruiting a postdoc fellow soon. More information coming soon!! PS: Till then this little fella is in-charge of all experiments 😂 #academic #newPI #postdoc #jobs @LSUHealthNO @LSUHS @LSUHS_Micro
Image from Sadiya Parveen-Nesson (@sadiyarsh)
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Big congratulations to @sadiyarsh ; the freshly minted assistant professor from Bishai Lab!! We can't be prouder and are looking forward to all the amazing science coming out of Parveen Lab 😀😎!! #EndTB #AcademicTwitter #TBresearch
Sadiya Parveen-Nesson (@sadiyarsh) profile pictureSadiya Parveen-Nesson@sadiyarsh19 Sep 2024
The nerve-wracking yet exciting next step of my career: starting as a tenure-track assistant professor at Louisiana State University Health. Can’t express how grateful I am to my mentors and my community 🥰!! @BishaiLab @Jack02646576 @BarbaraSSlusher
Image from Sadiya Parveen-Nesson (@sadiyarsh)
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#KStuberculosis24: @BishaiLab closes morning session with beautiful study dissecting hormonal vs. genetic sex-specific differences in #tuberculosis infection with the FCG mouse model, identifying significant differences in pathology, immune cell recruitment, inflammatory response
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Ahead of #WorldTBDay, there is no better opportunity to raise awareness than attending @KeystoneSymp Tuberculosis and exploring emerging #mycobacteria
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The JHU brigade at @KeystoneSymp 2024 @SanjayJain_Lab #KStuberculosis2024 #TBresearch #Tuberculosis #TB #EndTB
Image from Bishai Lab (@BishaiLab)
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A big thanks to all authors, our amazing collaborators Drs. @BarbaraSSlusher, Jonathan Powell, Bob Leone, Rana Rais and @JohnsHopkinsDOM @JHMed_ID @HopkinsMedicine #TB #TBresearch #EndTB #tuberculosis
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A big thanks to all authors and our amazing collaborators Drs. @BarbaraSSlusher, Jonathan Powell, Bob Leone, Rana Rais and their teams #TBresearch #EndTB #tuberculosis
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Morning Read: The Mycobacterium #tuberculosis genome at 25 years: lessons and lingering questions pubmed.ncbi.nlm.nih.gov/3778… @BishaiLab #IDTwitter
The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions - PubMed

The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions - PubMed

First achieved in 1998 by Cole et al., the complete genome sequence of Mycobacterium tuberculosis continues to provide an invaluable resource to understand tuberculosis (TB), the leading cause of...

pubmed.ncbi.nlm.nih.gov
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Morning Read: Sex and Gender Differences in #Tuberculosis Pathogenesis and Treatment Outcomes pubmed.ncbi.nlm.nih.gov/3769… @BishaiLab
Sex and Gender Differences in Tuberculosis Pathogenesis and Treatment Outcomes - PubMed

Sex and Gender Differences in Tuberculosis Pathogenesis and Treatment Outcomes - PubMed

Tuberculosis remains a daunting public health concern in many countries of the world. A consistent observation in the global epidemiology of tuberculosis is an excess of cases of active pulmonary...

pubmed.ncbi.nlm.nih.gov
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A day filled with insightful talks, anecdotes about Jack, nostalgia, laughter, and fun. Thanks to all of you who could make it to #MurphySymposium! @JHMed_ID @HopkinsMedicine @AlvaroAOrdonez @SanjayJain_Lab @sadiyarsh @gwenbmurphy
Image from Bishai Lab (@BishaiLab)
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@dpardol1
Please join us in celebrating 81st birthday and scientific legacy of Dr. John R Murphy (aka Jack), the pioneer of the Diphtheria fusion protein toxin research and molecular genetics of Diphtheria tox repressor, DtxR. @JHMed_ID @HopkinsMedicine
Johns Hopkins Division of Infectious Diseases (@JHMed_ID) profile pictureJohns Hopkins Division of Infectious Diseases@JHMed_ID5 Oct 2022
LIVE Tues 10/11 12:30-5pm: Infections & #Immunotherapy Symposium @BishaiLab @PittHealthSci #DrFadiLakkis @YaleMed #FrancineFoss #MyChronicCancer #NovaBioSystems #RobShickel @HopkinsMedicine @bloombergkimmel @dpardol1 Learn more, join live bit.ly/3RYJ1wZ
Image from Johns Hopkins Division of Infectious Diseases (@JHMed_ID)
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Here is our brand-new review on "Genetic and hormonal mechanisms underlying sex-specific immune responses in tuberculosis" authors.elsevier.com/c/1fPGR…
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A new candidate vaccine against NMIBC in a multi institutional study in close collaboration with @tbivala1 Re-engineered BCG overexpressing cyclic di-AMP augments trained immunity and exhibits improved efficacy against… disq.us/t/457gd6d
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Preprint of our recent finding showing 'BCG conferred protection against SARS-CoV-2' @Yegnalab @tbivala1 @SanjayJain_Lab Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation biorxiv.org/content/10.1101/…
Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease...

Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease...

COVID-19 continues to exact a toll on human health despite the availability of several vaccines. Bacillus Calmette Guérin (BCG) has been shown to confer heterologous immune protection against viral...

biorxiv.org
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Great sesion on BCG and cancer at 100 years of BCG cong to @ImmunoBladder @BishaiLab and #MTBVAC to @edumoreo 👍
Molly Ingersoll (@ImmunoBladder) profile pictureMolly Ingersoll@ImmunoBladder19 Nov 2021
Wrapping up 2 day symposium marking 100 years since the 1st #BCG vaccination covering vaccination to cancer to ‘off-target’ protective effects of BCG. Pictured: Bonus medical instrument exhibit at the hotel-syringes to clean the bladder & fellow speakers in the cancer session.
Image from Molly Ingersoll (@ImmunoBladder)
Image from Molly Ingersoll (@ImmunoBladder)
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Replying to @steffikrug
@steffikrug, I can’t tell you how grateful I am to my amazing mentors @BishaiLab @Jack02646576 and my wonderful colleagues like you. Thank you for sharing 😍😍.
Stefanie Krug (@steffikrug) profile pictureStefanie Krug@steffikrug4 Jun 2021
Replying to @steffikrug
And a heartfelt congratulations to this (and last) year's recipients of the Arthur M. Dannenberg, Jr. Award for TB research, @sadiyarsh, Monika Looney and Katherine Robsky! 👏🎉💐 Well-deserved recognition of 3 amazing, enthusiastic and brilliant scientists!
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Excited for a great day of #TB research and keynote speaker @mbehr_mcgill at the Johns Hopkins TB Center Annual Scientific Meeting!
Image from Stefanie Krug (@steffikrug)
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