Academic Clinical Lecturer in Haematology @MRC_WIMM, @OUHospitals, Oxford. Previously @PapaemmanuilLab, NYC. Interested in all things myeloid and BMT.
Oxford, UK
Joined December 2013
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🚨🚨Paper out! 🚨🚨
Delighted to share our work, now published in @NatureGenet 🧬! shorturl.at/94s5S
We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n
🧵👇
ALT Scientific illustration @ArbachHratch
Huge congratulations @LSommerova @Chapman_lab_UK - beautiful work and great to see this out!!!
Online Now: ATM safeguards DNA replication by restraining pathological repriming at endogenous base lesions dlvr.it/TVgxRM
Fantastic to see this paper out 🥳congrats @ARampotas, excited for what comes next!!
1/ 🧵 So delighted to share our new paper, out today in Science Translational Medicine @ScienceTM. We built a CAR-T cell therapy that selectively depletes the disease-driving mutant calreticulin (mutCALR) cells in myelofibrosis — while sparing healthy blood stem cells👇
science.org/doi/10.1126/scit…
Wholeheartedly agree! Brilliant conference - excited for the next one!
This field is so very special - it truly feels like a family. Thank you #MPNfriends for taking me in, fostering my career development, and being such wonderful friends and colleagues. Thank you @ESHaematology for a fantastic and meeting. Obrigato Portugal for being so welcoming!
It’s been a lot of fun acting as @JoselleCookMD's deputy in bringing #ASH25 ASHNewsDaily to life! Great to finally meet the team IRL today 😍
@ZanwarSaurabh
@EmperorBlackMD
@majorajay
@ChrisGrahamMD
@supriyaguptaMD
@ASH_hematology
Beautiful talks and overview of progress over many decades - even if the shade chosen for the surroundigns was eye-popping!
Terrific Ernest Beutler honorific lecture session #ASH25 by @mpdrc and Radek Skoda on discovery of JAK mutations and development of JAK inhibitors. Generous to collaborators in the #MPNsm community and key role of patients, very classy. And the room was such lurid green ala #Wicked that I was waiting for someone to start soaring around on a broom and singing “Defying Gravity”! 🧙 🤪
Congrats to Dr Fathi and team for delivering this investigator initiated trial. A pleasure interviewing and getting the scoop for ASH News Daily!
Huge congratulations to Amir Fathi for delivering one of the most impactful plenary presentations @ASH_hematology in AML in past decade. The PARADIGM study may lead to a Paradigm shift- Aza/Ven > intensive chemo in newly Dx high-risk AML. 👏👏👏
Charlotte Brierley retweeted
MEET THE FACULTY OF #ESHMPN2026!
11th Translational Research Conference
Myeloproliferative Neoplasms
April 24-26, 2026/Estoril, Portugal
Chairs:@jjkiladjian @rosslevinemd @MullallyLab @jyoti_nangalia
More information➡️bit.ly/4litFm1
#ESHCONFERENCES #MPNsm
Charlotte Brierley retweeted
Understanding leukemic transformation: biology insights from @CKBrierley @VJHemOnc #iwMDS25 #iwMPN25 #LeukemicTransformation #MPN
Charlotte Brierley retweeted
Fantastic discussion from Adam Meade, @CKBrierley & Juan Carlos Hernandez-Boluda who covered novel ideas on blastic phase and transplantation #iwMDSMPN25 🩸 📷
Full discussion will be posted soon on VJHemOnc.com 📷
We are incredibly grateful for fantastic support from institutions and funders, critical to enabling this work:
@CR_UK @LeukUK @wellcometrust @MRC_WIMM @RDMOxford @MSKCancerCenter
@StJude