Johnathan Canton (@CantonJohnathan) header
Johnathan Canton (@CantonJohnathan) profile picture

Johnathan Canton

@CantonJohnathan

Assistant Professor at the University of Calgary. @cantonjohnathan.bsky.social

 Calgary, Alberta, Canada
vet.ucalgary.ca/labs/cantonlab/home
Joined June 2021
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  • Following230
  • Followers240
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Photo by Johnathan Canton (@CantonJohnathan)
Excited to share that our story on apolipoprotein control of cross-presentation is now published in @SciImmunology and can be found here science.org/doi/10.1126/scii… Congrats first authors @GeroneGon , @Liam_Wilki and Song Huang, as well as @_Cassie_Wood and xless authors too. 😊
The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by...

The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by...

The apolipoprotein APOL7C is recruited to phagosomes to deliver engulfed antigens to the cytosol for cross-presentation by cDCs.

science.org
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We have a new episode out now! Tune in to hear Dr. Johnathan Canton (@CantonJohnathan) from @UCalgary discuss advanced microscopy techniques, mechanisms of #DendriticCell cross-presentation, and running a farm in Belize! 📍 bit.ly/3Gu9UIF
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Johnathan Canton retweeted
Spencer Freeman (@spencerSK1) profile picture
Spencer Freeman@spencerSK127 Feb 2025
We've been studying mechanisms of resilience that protect lysosomes from damage and wrote a review on the topic. We consider lysosomal stress and damage on a spectrum; hopefully a useful concept😀. Snapshot below and Open Access here: embopress.org/doi/full/10.10…
Image from Spencer Freeman (@spencerSK1)
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Johnathan Canton retweeted
UCalgaryMedicine (@UCalgaryMed) profile picture
UCalgaryMedicine@UCalgaryMed14 Nov 2024
🎉 Celebrating the tremendous developments in immunotherapy research led by Dr. Doug Mahoney and @Charb_Cancer researchers. The results of a generous $9.5M gift from the Canadian Cancer Society that has accelerated research for rare cancers. Read more: bit.ly/3YPGOIB
Image from UCalgaryMedicine (@UCalgaryMed)
Image from UCalgaryMedicine (@UCalgaryMed)
Image from UCalgaryMedicine (@UCalgaryMed)
Image from UCalgaryMedicine (@UCalgaryMed)
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Research from Dr. Jonathan Canton and his team sheds light on how specialized immune cells act as sentinels, providing a critical defense against infections. ucalgary.ca/news/ucalgary-re… #Immunology #PublicHealth @UCalgary @UCalgaryMed @ucalgaryvetmed @CantonJohnathan @GeroneGon
UCalgary research reveals how special cells act as ‘sentinels’ of the immune system

UCalgary research reveals how special cells act as ‘sentinels’ of the immune system

Groundbreaking finding by Faculty of Veterinary Medicine team opens door to new immunotherapies and enhanced vaccines

ucalgary.ca
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Very cool positions available in a very cool lab!
Evangelos Giampazolias (@giampazolias) profile pictureEvangelos Giampazolias@giampazolias4 Nov 2024
💥Exciting @ERC_Research funded postdoc opportunities in my lab at @CRUK_MI to study nutrient-host-microbiome interactions in cancer immunity in mice and humans. #CancerImmunology #MucosalImmunology #Microbiome ⏰Deadline: 1 December 2024 Apply 👇 cruk.manchester.ac.uk/recrui… ⏩RT
Image from Evangelos Giampazolias (@giampazolias)
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New research in Science #Immunology identifies the pore-forming protein #APOL7C as a driver of phagosomal rupture and antigen cross-presentation in activated dendritic cells. @CantonJohnathan @GeroneGon @Liam_Wilki @_Cassie_Wood bit.ly/3CjeKWp
Image from Science Immunology (@SciImmunology)
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And a nice tweetorial from first author @GeroneGon 😊
Gerone Gonzales (@GeroneGon) profile pictureGerone Gonzales@GeroneGon1 Nov 2024
Very happy to share the latest work from the @CantonJohnathan lab at @UCalgary , out in @SciImmunology investigating how APOL7C leads to antigen escape in the phagosome-to-cytosol pathway of cross presentation in cDCs! (1/11) science.org/doi/10.1126/scie…
Image from Gerone Gonzales (@GeroneGon)
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Johnathan Canton retweeted
Gerone Gonzales (@GeroneGon) profile picture
Gerone Gonzales@GeroneGon31 Oct 2024
Paranormal science in the @CantonJohnathan lab 👻 #HappyHalloween #madscientists
Image from Gerone Gonzales (@GeroneGon)
Image from Gerone Gonzales (@GeroneGon)
Image from Gerone Gonzales (@GeroneGon)
Image from Gerone Gonzales (@GeroneGon)
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Explore research in Mass Spectrometry & Spatial Genomics! Register now: forms.office.com/r/EUA4ZuDAT… For more details, feel free to reach out at infection.biology@ucalgary #Symposium #InfectiousDisease #ResearchInnovation @ucalgaryvetmed @UCalgary @UCalgaryMed
Image from Snyder Institute for Chronic Diseases (@SnyderInstitute)
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Johnathan Canton retweeted
Katha Lahl (@katha_lahl) profile picture
Katha Lahl@katha_lahl24 Sep 2024
Here's the latest in greatest (I think...😃) from our lab! If you end up having a look and have any comments I'd love to hear them! Maternal immunity protects offspring from enteric viral infection without negatively affecting humoral immune memory biorxiv.org/content/10.1101/…
Maternal immunity protects offspring from enteric viral infection without negatively affecting...

Maternal immunity protects offspring from enteric viral infection without negatively affecting...

Passive transfer of antibodies can effectively protect newborns from dysbiosis and infection but has also been proposed to inhibit intrinsic immune onset in the protected child. Yet, some early...

biorxiv.org
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Great summary of our paper news.ucsb.edu/2024/021575/ap… 🙏 @ucsantabarbara
An appetizer can stimulate immune cells’ appetite, a boon for cancer treatments

An appetizer can stimulate immune cells’ appetite, a boon for cancer treatments

UC Santa Barbara researchers found that priming the appetite of macrophages can boost how much they consume later. This discovery could lead to more effective immunotherapies.

news.ucsb.edu
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A nice article in The Scientist highlighting our recent work. the-scientist.com/vitamin-d-…
Vitamin D Acts via the Microbiome to Boost Cancer Immunity | The Scientist

Vitamin D Acts via the Microbiome to Boost Cancer Immunity | The Scientist

An essential nutrient and the gut flora, thought to have separate but important roles in the immune response, join forces.

the-scientist.com
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Still early days, but this was a nice opportunity to take stock of the journey so far. Thanks for the invite @LabListon and @ImmunolCellBiol. And a nod to Belizean scientists @fwfonseca16 @belizemoecst onlinelibrary.wiley.com/doi/…

Immunology & Cell Biology | ASI Journal | Wiley Online Library

This manuscript describes the winding career path of Dr Johnathan Canton – an Assistant Professor at the University of Calgary and recent recipient of the Bhagirath Singh Early Career Award from the...

onlinelibrary.wiley.com
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Expanding the plasma membrane in #neutrophils and #macrophages increases their ability to engulf bacteria, fungi, and #cancer cells. @UCSF @MSKCancerCenter Learn more: scim.ag/7fY
Image from Science Immunology (@SciImmunology)
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Johnathan Canton retweeted
Katha Lahl (@katha_lahl) profile picture
Katha Lahl@katha_lahl30 Apr 2024
A long time in the making, here is our study describing the role of Bcl6 in DCs. What started as the simple wish to correct my previous assumptions turned into something much more exciting. It's about time to see this out in the open! doi.org/10.1038/s41467-024-4… (1/7)
Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises...

Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises...

Nature Communications - Conventional dendritic cells are playing a pivotal role at the interface of innate and adaptive immunity, but they are a heterogenous group regarding function and...

nature.com
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MIID and @UCalgaryMed @SnyderInstitute @ucalgaryvetmed represented at #CSI2024
Image from Microbiology, Immunology, and Infectious Diseases (@MIID_UCalgary)
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Early Career Investigators Dr. Ajitha Thanabalasuriar (@AjithaT4) and Dr. Johnathan Canton (@CantonJohnathan) present outstanding research made possible by @CIHR_IRSC funding 🎉 #CSI2024
Image from Canadian Society for Immunology (@CdnImmunol)
Image from Canadian Society for Immunology (@CdnImmunol)
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Johnathan Canton retweeted
Charu Kaushic (@CKaushic) profile picture
Charu Kaushic@CKaushic24 Apr 2024
Pleasure to attend and host the Bhagi Singh Award session at the 36th #CSI2024 conference in Banff! Special thanks to @AjithaT4 & @CantonJohnathan for highlighting excellence in #ECR research and to the fantastic organizing committee for partnering with @CIHR_III. @MarkusGeuking
Image from Charu Kaushic (@CKaushic)
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Johnathan Canton retweeted
Francis Fonseca (@fwfonseca16) profile picture
Francis Fonseca@fwfonseca1622 Apr 2024
Image from Francis Fonseca (@fwfonseca16)
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