Alberto Ceccarelli retweeted
🧵 New protocol out in @STARProtocols! We present a step-by-step guide for inferring mechanical stresses in tissues using ForSys, by @BorgesAugust, @hey_jero, @CeccarelliAS, @gbventur, @ksedzinski, @LopezSchier365 & @Osvaldo_Chara
cell.com/star-protocols/full…
Alberto Ceccarelli retweeted
Thrilled to share this adventure on how zebrafish elongates its notochord! 🐟 Kudos to Carlos Camacho de la Macorra and @BenSteventon2 for leading it. @CeccarelliAS and I had so much fun modelling & uncovering unexpected predictions...
biorxiv.org/content/10.64898…
Alberto Ceccarelli retweeted
The code is available at
github.com/borgesaugusto/for… . We welcome any and all feedback 😁
Stay tuned for more upcoming projects 😉!
(10/10)
Alberto Ceccarelli retweeted
Our ForSys method to infer the mechanical state of a tissue in space and time is published now in @iScience_CP!
cell.com/iscience/fulltext/S…
(1/10)
Alberto Ceccarelli retweeted
I would like to thank all my amazing colleagues @borgesaugust, @hey_jero, @CeccarelliAS, @gbventur, @ksedzinski, and @LopezSchier365, as well as the reviewers, the editorial team of @iScience_CP and the community for their support.
(9/10)
Alberto Ceccarelli retweeted
We’re also grateful to the Editor and Reviewers for their helpful feedback. We hope this study contributes to a deeper understanding of how cells regain their place in a regenerating organ.
Thanks for reading! 🙌
(n/n)
Alberto Ceccarelli retweeted
This work was made possible by a stellar team: Hernan Arce (PhD), @CeccarelliAS (postdoc), @RepreARG (Diploma student) from my lab and our collaborators Catarina Oliveira, and @MaxYunLab . Huge thanks to all!
(12/n)
Alberto Ceccarelli retweeted
Cells in a regenerating axolotl limb somehow know their place—but how?
In our new paper, we trace the dynamics of positional memory, release open-source code to quantify it, and introduce a theoretical framework for proximalisation.
🧵👇
🔗 nature.com/articles/s41598-0…
(1/n)
Alberto Ceccarelli retweeted
A few minutes ago @CeccarelliAS defended his PhD at the University of La Plata! Congratulations Dr Ceccarelli!!!
His defence (in Spanish) at this link:
youtube.com/live/J5FsoxAzjhQ
Alberto Ceccarelli retweeted
🔬Curious about how to achieve an organ-wide regenerative response through locally controlled cell proliferation? Check out our latest preprint, which computationally addresses this problem in the neuromast within the zebrafish lateral line.
biorxiv.org/content/10.1101/… (1/9)
Alberto Ceccarelli retweeted
Our new adventure on how Shh+ floor plate cells contribute to spinal cord regeneration along the dorsal-ventral axis in our beloved axolotl is now ready for you! The heroes of this story are my amazing colleagues and friends @lauraarbanas, @LeoOtsuki, @CuraCosta and @Tanaxolotl!!
Our paper, "Lineage tracing of Shh+ floor plate cells and dynamics of dorsal–ventral gene expression in the regenerating axolotl spinal cord" is now out, open access, in DGD! onlinelibrary.wiley.com/doi/….
Alberto Ceccarelli retweeted
The great @CeccarelliAS starts his position in our group! Welcome Alberto! Here we have one with our collaborator and friend @AlberioRamiro!
Alberto Ceccarelli retweeted
We present ForSys, a new method to portray the mechanical state of a tissue in space and time!!
biorxiv.org/content/10.1101/…
(1/11)
Alberto Ceccarelli retweeted
Our software, ForSys, is finally out as a preprint! I am thrilled to have worked on this fantastic story. I want to thank @hey_jero, @CeccarelliAS, @gbventur, @ksedzinski, Hernán López-Schier, and @Osvaldo_Chara for this amazing journey. Stay tuned for more!
We present ForSys, a new method to portray the mechanical state of a tissue in space and time!!
biorxiv.org/content/10.1101/…
(1/11)
Alberto Ceccarelli retweeted
In between the dynamical phases of #tissue growth and decay the tissues are in #homeostasis, which we showed that can be considered a state of #criticality.
(1/4)
Alberto Ceccarelli retweeted
Would you like to know if spinal cord regeneration in the axolotl could be explained by a Reaction-Diffusion signal? If yes, check out our new adventure: biorxiv.org/content/10.1101/… #bioRxiv
(1/n)
How a reaction-diffusion signal can control spinal cord regeneration in axolotls: A modelling study biorxiv.org/cgi/content/shor… #bioRxiv
Alberto Ceccarelli retweeted
Is critical a tissue during homeostasis?
Can a toy Markovian model describing the cells as (stupid) entities that don't "remember" where they are in the cell cycle actually represent a non-Markovian model of tissue growth? Check out our last adventure in bioRxiv!
(1/11)
Fluctuations in tissue growth portray homeostasis as a critical state and long-time non-Markovian cell proliferation as Markovian biorxiv.org/cgi/content/shor… #biorxiv_biophys
Alberto Ceccarelli retweeted
When is it OK to assume a tissue as infinite? Read the last article from Chara's lab by @CeccarelliAS , @borgesaugust and @Osvaldo_Chara about spatiotemporal distribution of morphogens!
royalsocietypublishing.org/d…
(1/9)
Size matters - tissue size as a marker for a transition between reaction–diffusion regimes in spatio-temporal distribution of morphogens: ow.ly/lHS350HFrzc #RSOS #OpenAccess #ComputationalBiology #biophysics
Alberto Ceccarelli retweeted
Happy to share our adventure on the mechanisms of spinal cord regeneration in the axolotl. We combined amazing computational modelling from @CuraCosta and the fantastic AxFUCCI from @LeoOtsuki, in collaboration with the great @aidarodrigo and the always inspiring @tanoxolotl!!
Axolotls have the rare ability to regenerate their spinal cord. Researchers have used models, tightly linked to experimental data, to help investigate the mechanisms and signalling underlying spinal cord regeneration elifesciences.org/articles/5…
ALT Illustration of an axolotl next to a model of cell dynamics along the cord
Alberto Ceccarelli retweeted
Are you curious about how axolotls grow and age? Check out the latest adventure of @_CamiloRG and colleagues from the @TatiSandGuz
xitter.cf/_CamiloRG/status/14094…