Immunology with a touch of regenerative medicine. Thymus enthusiast @fredhutch (previously seen around @MonashUni & @MSKCancerCenter) 🇦🇺 in 🇺🇸
Seattle, WA
Joined April 2017
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With a mix of pride, enthusiasm, and tremendous relief, I present our latest paper that describes the emergence of atypical epithelial cells in the thymus with age that limit the tissues function at steady-state and its repair after damage… 1/?
nature.com/articles/s41590-0…
[To the three scientists still left here]:
Interested in T cells and where they come from? Then now is the perfect opportunity to register for ThymUS (thymusmeeting.org). Don't miss out on what is shaping up to be a fantastic meting in gorgeous Kauai.
Dudakov Lab retweeted
#Immunology by First release now @ScienceMagazine
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
buff.ly/3DjNQ1e
By @CicaCanesso, @victora_lab, @danmucida and colleagues.
Dudakov Lab retweeted
Age-related decline in CD8+ tissue resident memory T cells compromises antitumor immunity
@NatureAging
nature.com/articles/s43587-0…
Dudakov Lab retweeted
🚨Out now in @Nature: Our spatial atlas of the developing thymus nature.com/articles/s41586-0…
Together with @Teichlab @MarioniLab and Germain lab we present insights into the establishment of the thymic organ structure in pre- and postnatal life through a new spatial mapping approach.
Dudakov Lab retweeted
Specialized fibroblastic reticular cells underpin interconnected T cell environments with dedicated microenvironmental niches that promotes antitumor immunity in lung cancer @CellCellPress @ImmunobiologySG
cell.com/cell/fulltext/S0092…
Dudakov Lab retweeted
Early-life thymectomy leads to an increase of granzyme-producing γδ T cells in children with congenital heart disease @SarinaRavens
nature.com/articles/s41467-0…
Dudakov Lab retweeted
New @CellCellPress resource:
Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging
cell.com/cell/fulltext/S0092…
Impressive dataset of aging associated transcriptomics alterations across multiple tissues that identifies immunoglobulin-associated senescence (IgGAS) as a marker of aging.
Conducted using the @ST_Omics Stereo-seq platform.
Dudakov Lab retweeted
Its great to be able to finally share our work identifying and examining CTLA4 expression by ILCs and its roles in regulating mucosal homeostasis!
nature.com/articles/s41467-0…
Dudakov Lab retweeted
New Review from @Muzz_Haniffa and colleagues @sangerinstitute explains how the prenatal immune system develops
rdcu.be/dZcJn
This is one of the coolest data vis graphics I’ve ever seen.
It's 4:00 AM. While LinkedIn warriors post about their "morning hustle," real data tells a different story. One thousand dots. One thousand real Americans. Not influencers. Not motivational speakers. Just actual people, captured in the American Time Use Survey by the US Bureau of Bureau of Labor Statistics.
Second place finishers in the @fredhutch Steamplant lab group costume contest for a second year running. Robbed.
Dudakov Lab retweeted
Stem cell transplants are amazing. A patient's diseased blood is replaced by a relative or stranger's. But what does putting a blood system into a new body do to the cells? How many survive? Does it matter?
Out in @Nature today, we asked some basic Qs 👇
rdcu.be/dYCoZ
Growing up in Australia I’ve always been uncommonly interested in US politics (even majored in it in undergrad) so it was an auspicious day to vote for the first time as an immigrant scientist in this country.
Dudakov Lab retweeted
🎉Finally out! Many congrats to Savvas Savvidis, @RobertaRag80163 ,Valeria Conde de Rafael & all co-authors @ucl & @TheCrick for unraveling the human #thymus #development in #3D !
I am grateful for a fantastic experience @esrfsynchrotron in Grenoble
nature.com/articles/s43856-0…
Dudakov Lab retweeted
Are you the next team member to join us? More than your credentials, we are looking the right person! Both post-docs or PhD students are welcome. Come solve some fundamental issues of the human thymus biology with us! #recruiting #academicjobs #hiring #postdoc #phdcandidate
Dudakov Lab retweeted
Online now!✨RESEARCH: Jing, Song and colleagues uncover METTL3 as a regulator of and potential target in thymic involution, where it regulates ferroptosis signaling nature.com/articles/s43587-0… rdcu.be/dXOEU
What a great opportunity! Eliisa is an amazing physician-scientist working on some very cool projects (and could quite possibly be even more of a thymus enthusiast as I am!).
I am recruiting! Are you looking #postdoc position and are interested in #thymus ? I’m hiring two postdocs to work in our @ERC_Research funded new project ProtecTHY where we want to learn how the thymus protects itself during HSCT. Shares appreciated! jobs.helsinki.fi/job/Helsink…
Dudakov Lab retweeted
Sex-based differences in thymus biology and T cell development arise before puberty, providing an essential contribution to our understanding of the mechanisms underlying immune function and dysfunction in males and females @Dev_Cell @PZandstra Rossi
cell.com/developmental-cell/…
Cloud thymus hot on the heels of our Black Hole Thymus @NatImmunol cover! What a time to be alive!
New issue online! This beautiful cover depicts work from @maxim_artyomov, Pavla Bohacova, Marina Terekhova &co identifying CD38 expression as a marker of recent thymic emigrants. Image credit: Fishy Frog cell.com/immunity/issue?pii=…
