EFFECT Trial: Efficacy of Flucytosine & Fluconazole as Early Cryptococcal Treatment. Phase 3 RCT at 13 sites in South Africa, Tanzania, Vietnam. Funded @The_MRC
Joined February 2022
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We are thrilled to share that we are down to double digits! 99 participants left to reach out recruitment target of 600. Looking forward to contributing meaningful data to help to #EndCryptoDeaths 🦠🏥💯
@neleshg @sile47742 @JNJarvis76 @KylaMurphyZA
We are thrilled to share our latest EFFECT newsletter, which can be viewed here:
sway.cloud.microsoft/dnmKOOI…
Take a look at what we've been up to over the past few months to #EndCryptoDeaths
EFFECT Trial retweeted
Great week in S Africa @MSF_southafrica discussing all things cryptococcosis, histoplasmosis & advanced HIV disease. Now @WitsUniversity where I gave a lecture on interdisciplinary research within @IMPRINT_NIHRGHR & met @neleshg & our @EffectTrial social science team @NIHRglobal – at Johannesburg, South Africa
sway.office.com/9a9ofCjK8MWp…
Take a look at what we've been up to, in our latest EFFECT newsletter! It's been an exciting few months, and we are looking forward to an inspired 2024, working to #EndCryptoDeaths
EFFECT Trial retweeted
Thrilled that today @JNJarvis76 and I were able to represent the huge and wonderful @ambitioncm2020 team and receive the @EACSociety European Hector Research Award for best clinical/epidemiological paper in HIV in the last two years. Dedicated to all participants #EACS2023 – at Warsaw, Poland
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A fantastic morning today, hearing from our Community Advisory Board and a study participant's perspective, reminding us of the importance of ensuring we translate our work from bench to bedside, to #endcryptodeaths
Our second Investigators Meeting starts in Cape Town today! Wonderful to have so many team members here in person, looking forward to a fantastic few days of reflection, collaboration and inspiration for the way forward to #endcryptodeaths
EFFECT Trial retweeted
Is fluconazole enough for cryptococcal antigenaemia? The @EffectTrial is exploring the impact of flucytosine plus fluconazole in South Africa and Tanzania. Thrilled to be part of this wonderful team! – at Plumpton, England
St George’s researchers are leading an international trial which aims to improve treatment to prevent a type of meningitis that attacks the brain in people with advanced HIV, thanks to £4.5m funding from @The_MRC.
Learn more about the @EffectTrial: sgul.ac.uk/news/4.5m-interna…
ALT Dr Síle Molloy from SGUL and Professor Nelesh Govender from the University of the Witwatersrand.
EFFECT Trial retweeted
St George’s researchers are leading an international trial which aims to improve treatment to prevent a type of meningitis that attacks the brain in people with advanced HIV, thanks to £4.5m funding from @The_MRC.
Learn more about the @EffectTrial: sgul.ac.uk/news/4.5m-interna…
ALT Dr Síle Molloy from SGUL and Professor Nelesh Govender from the University of the Witwatersrand.
We're pleased to share the 3rd edition of our EFFECT newsletter, which can be viewed here: sway.office.com/Mi38zXlqF5kA…
And a massive congratulations to our sites for reaching 100 enrolled participants, a fantastic achievement towards our goal to #endcryptodeaths. Onward to 600!
We are excited to share our 2nd newsletter with you all!
sway.office.com/BwZbCgevJzg5…
EFFECT Trial retweeted
Incredible week at the #ICCC in Kampala. Glastonbury for #cryptococcus! Great to connect with amazing colleagues, make new friends and discuss future collaborations. Phenomenal organisation by the team! – at Kampala, Uganda
Valuable insights from @drdavidlawrence on patient perspectives of the @ambitioncm2020 regimen.
Bottom line: staff and patients prefer a single dose of L-Amb.
"They want one yellow, not 7 yellows"💉🟡
Now to push for implementation with @SHARECM1 and @IMPRINT_NIHRGHR
🧫🦠🧠
Our co-CI @neleshg presenting on CrAg screening programmes, in which the EFFECT trial is embedded. Our other co-CI @Molloy_Sile presented @EffectTrial earlier this morning during the #ICCC2023 Clinical Track CrAg Screening sessions. Working our way to #endcryptodeaths by 2030💉💊
Many of our investigators are participating in #ICCC2023 in Kampala this week. Today, a master class in the clinical management of cryptococcal meningitis with @drdavidlawrence @KylaComins and colleagues from @SHARECM1 discussing implementation of the @ambitioncm2020 regimen 💊💉
EFFECT Trial retweeted
I am so excited for this trial taking place in Tanzania for a probable better treatment for PLHIV with Crypto….
We are so pleased today to be opening our next 3 @NIMR_Tanzania sites in Amana, Temeke and Mwananymala, Dar es Salaam, Tanzania. Our 8 South African sites are open and we have enrolled 15 participants to date. Looking forward to the next 585!
EFFECT Trial retweeted
Super excited to be working on the #HealthEconomics aspect of this project.
#EEACTs #EconomicEvaluation #Modelling #HTA #clinicaltrials
Fantastic to have experts from @uctphm Health Economics Division collaborating in the @IMPRINT_NIHRGHR group and assisting on our @EffectTrial health economics substudy with @ucl and @LSTMnews
Fantastic to have experts from @uctphm Health Economics Division collaborating in the @IMPRINT_NIHRGHR group and assisting on our @EffectTrial health economics substudy with @ucl and @LSTMnews