Research, education & medical care in #autoimmunity and #cell therapy at @DrOlivierBoyer_lab @Inserm @univrouen @CHURouen : #myositis, #pemphigus, #CAR T cells
Rouen
Joined March 2024
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focisnet.org/education/focis…
Designing and monitoring immunotherapies: from mechanisms to clinical translation
Fantastic FOCIS advanced course in Montevideo 🇺🇾
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
Karl Deisseroth, Peter Hegemann and Georg Nagel win the 2026 Nobel Prize in Physiology or Medicine for their work on optogenetics, which has revolutionized neuroscience
go.nature.com/4zk3Rfz
FOCIS provides highest level education in immunology in many parts of the world. Congratulations to the FOCIS Goes North team for incredible course in Iceland.
Where else? FOCIS Goes South 13-15OCT2026 in Montevideo. See you there.
focisnet.org/education/foci…
@Focis_FCE
Today is the final day of FOCIS Goes North: Iceland Cancer Immunology Conference🧬
It's been an inspiring few days of fascinating science, meaningful discussions, and great connections with colleagues from Iceland & around the world.
#FOCISGoesNorth #CancerImmunology
Splendid work about the role of TIF1γ in Tregs, a multifaceted molecule since autoantibodies targeting TIF1γ are associated to a risk of cancer in #dermatomyositis
@TheMyositisAssc @Telethon_France @iuis_online @FOCISimmunology
TIF1γ is a critical regulator of Treg cell stability that restrains β-catenin–TCF7 signaling, thereby preserving Foxp3 expression and preventing inflammatory reprogramming @NatImmunol
nature.com/articles/s41590-0… @LabLiconaP🇲🇽@IFC_UNAM
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
Proud to share our new piece in Blood Global Hematology, written with wonderful colleagues: @RobertaDemiche3 @castro_mollo @XimeJordan
"Hispanic/Latino" was built for policy, not biology. In leukemia, treating it as one group hides real diversity in ancestry, access & disease.
Rethinking Hispanic/Latino as an ethnic category in leukemia research ashpublications.org/bloodglo…
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
Excited to share our latest @ARD_BMJ study! We reveal the mechanism by which autoantibodies enter cells, disrupt their target autoantigens, and drive tissue injury and inflammation in myositis and other autoimmune diseases. 🧬
doi.org/10.1016/j.ard.2026.0…
Autoantibodies enter muscle cells & block target function. Plasma cells may transfer Ig mRNA to muscle cells and cause disease. A new mechanism in #autoimmunity elucidated by @DrIagoPinal et al.
@NIH @HopkinsMedicine @FOCISimmunology @iuis_online @Immunopaedia @TheMyositisAssc
#autoantibodies (aAb) functionally block intracellular autoantigens in #myositis. Do aAb enter cells? They do. Check evidence from @DrIagoPinal and colleagues @eular_ARD. Brilliant!
researchgate.net/publication…
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
If you are at the #FOCIS2026 meeting and have questions about @FOCISimmunology, look for FOCIS Leaders wearing the "ASK ME ABOUT" pin.
Need a hand networking... grab a pin with the languages you speak, great way to start a conversation and share your #immunology work.
Want to share good vibes with people? Stay on the lookout for the motivational stickers!
Don't forget to share the exciting work you see at the meeting!
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
Presented at #ASCO26:
Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: nej.md/4nWaxvM
@ASCO
ALT Graph from a study published in the New England Journal of Medicine on daraxonrasib versus chemotherapy for metastatic pancreatic cancer. The x-axis represents months, and the y-axis shows the percentage of patients alive. Two lines indicate survival rates: daraxonrasib (blue) and chemotherapy (gray). The bottom section lists patients at risk over time. Title and journal logo are included.
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
Honored to be an elected member of the American Society for Clinical Investigation! @the_asci physician scientists are not a dying breed- we’re alive and kicking- and working on growing more! We will summit together! #thefutureisbright 💪
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
🚨We’re excited to spotlight a new publication from the FOCIS community—and that their research image is featured on the cover!
📝 Beta cell–targeted PD-1 agonist inhibits cell-mediated autoimmunity in pancreas tissue slices
zurl.co/AbMBQ
Honored to present the results of our research on #myositis at GCOM Lisbon
@DrOlivierBoyer
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
Gervais, Trespidi, Ferrari, Rovida, Cobat, Zhang, Casanova, Borghesi et al. show that, in 13 European, Middle-Eastern, and American cohorts, pre-existing autoantibodies neutralizing type I IFNs are causal for WNV encephalitis in about 40% of patients. hubs.la/Q046JZ5J0
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
🎉 Congratulations to the 2026 Advanced Course Travel Award recipients!
Their hard work has been recognized, representing Colorado, the U.S., and institutions around the world. We’re excited to celebrate their achievements in Aurora, Colorado! 🌎👏
#FOCIS #FOCISAC2026
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
CAR-T cell therapy seems to have reset the immune system and eased severe symptoms in eight children and adolescents with autoimmune disorders
go.nature.com/4qNUYGq
Remarkable #myositis study from Pinal-Fernandez, Mammen et al.
Congratulations Iago and Andy, you have discovered a new pathomechanism in autoimmunity!
@TheMyositisAssc @UKMyositis @FOCISimmunology @iuis_online
🧬🚨New in @medrxivpreprint: Spatial transcriptomics reveals mechanism of autoimmunity driven by internalized autoantibodies: antibody secreting cells induce antibody internalization, disrupt autoantigen function, and drive muscle damage and inflammation
doi.org/10.64898/2026.02.14.…
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
🧬🚨New in @medrxivpreprint: Spatial transcriptomics reveals mechanism of autoimmunity driven by internalized autoantibodies: antibody secreting cells induce antibody internalization, disrupt autoantigen function, and drive muscle damage and inflammation
doi.org/10.64898/2026.02.14.…
FOCIS-Center-of-Excellence(FCE)-PAn'THER retweeted
The FOCIS Advanced Course take's place next month - March 9–11, 2026, at the Benson Hotel & Faculty Club in Aurora, CO!
Lock in unbeatable hotel rates before they’re gone!
🔗 Register: zurl.co/jCID6
