Gut First

A carrot is not a valid antimicrobial. A carrot is however highly fermentable (hello bloating), Carrot fiber doesn't possess the same LPS binding properties as MODIFIED citrus pectin. 95% of the benefit you're feeling from the carrot salad is just whatever you're putting on it, Coconut oil and monolaurin is a valid antimicrobial and biofilm agent, Vinegar has it's own benefits for the gut known for thousands of years. The carrot is just a handy carrier for the therapeutic dressing you put on it.

2 weeks of daily matcha and one butyrate producer doubled (+108%) with another up 76%. These bacteria make butyrate, the compound that when given directly: - Lowered abdominal pain - Reduced bloating - Lowered urgency of bowel movements Whole leaf gives the insoluble fiber that feeds them + high EGCG that can suppress pathogenic competitors. Cheap, easy, and one of the few trends I actually run with daily.

PEA was able to reduce the explosion of mast cells by up to 50%, For context those mast cells exploding are what often leads to intense, urgent and watery diarrhea. When mast cells burst they release their contents into the surrounding area, Histamine, destructive proteases and spasm inducing lipids all bind to local tissues causing the rapid flushing response in IBS-D. They also open up and damage the gut barrier leading to a sudden influx of water which you experience as loose stools, Then from there since mast cells live so close to nerve endings these inflammatory compounds bind to pain receptors. The irritated nerve endings release Substance P which when it comes into contact with mast cells causes further degranulation, Now back to the histamine, as more mast cells explode more histamine is in the surrounding area. This activated the h4r receptors, Now what makes this such a pain is that this activation leads to more mast cells and more sensitive mast cells drawn to the area. Okay by now you can see how this loop gets pretty bad, explosions leading to more explosions (both internally and in your bowel movements), So with PEA stabilising the mast cells you're helping to break the loop of things getting worse. Personally I like to pair it with black seed oil and quercetin, which have unique binding affinities for the h4 receptors again helping to stop the loop getting worse. (They also stabilise mast cells so win-win) So yeah histamine isn't just purely a allergy molecule, it's often what drives IBS-D and chronic loose stools that seem to evade everything you throw at them.

Take blood from a cow. Spin it real fast to separate the plasma, Extract the antibodies. Spray dry it into a powder. This powder: - Protects you against endotoxin/LPS by binding to it - Feeds butyrate producers leading to a stronger gut - Reduces Diarrhoea via stabilising the lining - Improved COVID recovery speed by up to 2x - Delayed/Lowered recurrence of SIBO - Increases certain beneficial microbes by up to 3.5x You can buy it online, even though it's expensive it's one of those supplements worth forking out for, You'll find it under Immunolin. in products like designs for health IgGI Shield, Better GI (when it's finally back in stock) and Mega IgG2000 powder. If you're running an antimicrobial protocol and worried about your lining, know your lining is an issue or have IBS-D this is one of the highest value interventions you can try.

Peaters when they find out PEA can help offset the damage from their aspirin use.

No doctor told me these when I was going through it, somebody should share these:

As your gut lining deteriorates opportunists and pathogens find it much easier to take hold, Loss of antimicrobial peptides regulating the microbiome is often a big culprit of this, Loss of mucus lining function and density also leads to perpetuation of this cycle, Damage to the gut lining also changes the oxygen environment, leading to certain species thriving that would not normally Alterations to motility via bacteria or gut lining damage again shift the environment in many pathogens favour, And from there pathogens and opportunists shift the environment even more in their favour via production of compounds they use for their own survival. The microbe may be the criminal, but your gut was the security that failed to prevent them from coming in and wrecking the place.

Anon discovers low stomach acid.

Ignore the crazy moustache but here is René Quinton, arguably one of the most important pioneers in functional medicine and terrain theory. As barbaric as it sounds, he removed about 75% of a dog's blood to bring them to the brink of death. Now, before you label him a monster, what comes next redeems him, He hooked the dog up to a drip and pumped back in marine plasma, which was cold filtered seawater precisely diluted to match the exact salinity of the dog's blood. Within minutes the dog was revived. Within days it was back to robust health. The dog, nicknamed Sodium, went on to live a completely healthy life for 5 years before being run over by a Paris tram. Now why do you care? Why on earth am I telling you all this? It's not about marine plasma therapy, but rather about the view of the body as a whole, His biggest observation is that although through evolution we left the ocean, the ocean never left us. Our blood plasma and ocean water share an almost identical ratio of trace minerals, albeit ocean water is obviously higher in salinity. He was obsessed with the internal environment instead of blindly attacking pathogens, focusing on rebuilding the terrain so the body's natural defenses could work. Sound familiar? He opened Quinton Marine Dispensaries which saved thousands of infants and adults during deadly cholera epidemics by rapidly restoring the body’s internal fluid environment, Survival outcomes during devastating outbreaks of TB and typhus were drastically improved by working on the quality of the terrain, rather than just treating the symptom, He became a monumental figure in proving the power of intravenous volume replacement, a foundational concept that underpins the modern saline drips saving millions of lives every year. So no, he wasn’t famous for "curing" or "killing." He was famous for restoring the body's own environment, and the clinical results spoke for themselves, You can still buy Quinton today, but the environment of your body extends far beyond simple hydration. Your stomach acid, your bile flow, your gut lining, these are the absolute pillars of your gut's natural internal environment, These are what regulate your digestion and fiercely protect you from the millions of opportunistic bacteria and pathogens you swallow every single day. I don't claim to be a genius like Quinton, but I can say that by focusing on restoring the internal terrain, I've seen countless people revitalize their health and finally resolve stubborn gut issues. A piece of Quinton's philosophy is embedded into every thought I have. Along with modern microbiome research and my own experience, I captured that blueprint, digitized it, and baked it into a personal gut assistant. I'm not claiming some magic cure like the dying dog got. What I can promise is that you'll learn to think about your gut issues in a proactive, protective way instead of constantly playing defense. You don't have to be a genius; you just need the right framework, GutFix is the tool for your terrain: gutfix.ai

Spoke to at least 12 guys like this in the past year.

Apparently gutty won't larp fake statistics in the free demo, useful instead of GPT pulling random niche studies which can mislead you, That being said inside the app we are actively working on features like this and already have some functionality for reading microbiome tests (no diagnosis, £30/month is for early waitlist users, new users £67/mo or check out the GutFix for life plan)

By the way I've enabled a few free messaged to my AI assistant at the end of the quiz, Just a sample question but ask it anything you like (besides for a diagnosis): gutfix.ai/quiz

If you want to learn more about how certain gene mutations can affect the gut, gutty actually was first built to think through situations like this. no diagnosis, just helpful information, You can speak to gutty at the end of the free quiz: gutfix.ai/quiz

The only way you can ever have "good gut health" is to have a gut that regulates itself, It does this through: - Stomach acid which nuetralises a vast majority of harmful bacteria - Bile which again neutralises many harmful bacteria in the small intestine - Low oxygen caused by the gut lining itself, which promotes a healthy microbiome - Antimicrobial peptides the gut lining secretes to balance the microbiome - Motility to avoid stalling and subsequent fermentation If any one of these factors are off it has a ripple effect through the entire system, Low stomach acid leads to more pathogenic bacteria surviving, but it also leads to poor bile flow which means they survive even more. These bacteria subsequently alter motility through gasses and also damage to the gut lining, which further reduces your bodies ability to regulate itself. Pathogens then create a niche environment where both their survival is favoured over "friendly microbes" and consistent damage to the gut lining prevents their clearance. When you take gut health out of the abstract and turn it into reality, you start to see how a healthy microbiome, motility and digestion are the baseline state, And the only thing preventing this from being possible is a feedback loop of all broken factors. Gut Health is not an abstract concept, it's a set of very physical and biological realities.

Much better for spinal allignment and therefore nervous system function.

Staring down at screens and phones may be one of the biggest risk factors for SIBO: Every 15 degrees you stare down you put roughly 5kg of pressure on your neck, Just this alone pinches on the vagal nerve, lowering vagal tone by up to 50%, Stomach acid directly requires the vagal nerve for parasympathetic states to be secreted properly, Low stomach acid = More bacteria survive + Poor bile flow = Small intestine is a prime breeding ground for bacteria. Restricting vagal nerve activity has been shown to slow motility by up to 40%, now leaving bacteria free and sitting in your small intestine for even longer, No wonder so many youths and professionals alike are getting SIBO. Place your devices at eye level. No looking down in the slightest, Neck massages to release, chin tucks to maintain. suboccipital releases daily for tension. Seriously your digestion and recurrence of SIBO will never improve if you don't have a body that can signal proper digestion, Take this seriously.

Many such cases.

2+2 = 4

Literally every convo I have with an IRL mutual when they find out what I do...