Structural Biochemistry @MPI_Bio & @UNI_TUE Understanding and Manipulating Molecular Machines

Tuebingen, Germany
Joined June 2020
Sleeves up for infection research: Our postdoc Joe Joiner researches anti-infectives to prevent #Salmonella infection. He’s not only appreciated as a talented researcher, but also as a great teacher by his students! @PAW_Germany #PostDocAppreciationWeek @MPI_Bio
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🥳🥳 Congrats, great job! 🥳🥳 Fantastic PhD defense by Joe this week, showcasing great results from your collaborative salmonella anti-virulence project with @samuwag @atposo @BronstrupLab! #Salmonella, beware of Joe! @phd_reps_MPI_DB
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We couldn't agree more - this is a fascinating topic and we are more than happy to provide the structural basis for the recognition of the C-terminal cyclic imide #degron in our new communication @BBRCME: sciencedirect.com/science/ar…
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2/4 Degron recognition is supported by a specific hydrogen bonding network that only involves the protein backbone of the last few amino acids preceding the C-terminal cyclic imide, allowing for the universal recognition of C-terminal #aspartimide and #aminoglutarimide residues
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Postdoc opening! We are looking for someone who can't wait to develop #mRNA-encodable peptide-based #PROTACs as next-generation therapeutics with us @MPI_for_DB & @UNI_TUE: eb.mpg.de/fileadmin/uploads/… RT appreciated.
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One student less, one postdoc more: After a great PhD defense, Chris earned his title today - congrats!🥳🥳🥳 Mind his #PROTAC building block amidosuccinimide on his hat! (Who needs #thalidomide anyway?) @phd_reps_MPI_DB
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AROM is a pentafunctional contortionist at the ❤️ of the #shikimate pathway. Down-to-earth conformational analysis solely based on the wealth of information in the PDB @buildmodels tells 1000 words @nchembio - rdcu.be/b5r7x - Kudos @AroraHarshul & Hongbo Zhu @MPI_for_DB
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