Kenn Samala (@KSamalaMD) header
Kenn Samala (@KSamalaMD) profile picture

🩺🧬Internal Medicine-Medical Oncology. @pghoncology 🇵🇭 🫁Thoracic Oncology Fellowship at Cross Cancer Institute. @crosscancer50 🇨🇦 @PSO1964 Vice-President, 2025

Edmonton, Alberta
Joined February 2022
Kenn Samala retweeted
1/ My top 7 thoracic picks for #ESMO26 (Madrid, Oct 23–27), ranked. @myESMO 5 of these phase 3s already announced positive toplines. ESMO is where we finally see effect sizes. The question each one answers 🧵 #LCSM @LungCancerRx @OncoAlert @oncodaily
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Kenn Samala retweeted
Five lung cancer trials to watch at #ESMO26: DeLLphi-305 KRAScendo 1 SAFFRON OptiTROP-Lung04 OptiTROP-Lung06 Encouraging signals. Full data matter: survival, CNS activity, toxicity and quality of life. Figure separates published evidence from sponsor toplines. #LCSM
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#ESMOAI25: Explore the latest AI-driven innovations in #oncology, brought to you by the #ESMOAmbassadors. Join the conversation on digital transformation in #CancerCare. #HealthAI 🔗 ow.ly/4V6z50XkYE6
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🔥BREAKING🆙 Positive OS‼️ ✅FLAURA2: Osimertinib + Chemo vs Osimertinib 🎯"Statistically significant and clinically meaningful improvement in the key secondary endpoint of OS" 🗣️@AstraZeneca @OncoAlert @Larvol #EGFR @EGFRResisters astrazeneca.com/media-centre…
PL03.13 Osimertinib With/Without Platinum-Based Chemotherapy as 1st-line Treatment in Pts with EGFRm Advanced NSCLC (FLAURA2) by Prof. Pasi Janne. Very important but huge space open for discussion. We need mature PFS2 and OS to discuss with pts. #LCSM #WCLC23 @IASLC @OncoAlert
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Kenn Samala retweeted
What great news for our EGFRm NSCLC patients, with a survival benefit that confirms the FLAURA2 regimen (Osi + ChemoT) as a new standard of care 1st-line ! We look forward to seeing the final OS data... #EGFR #lungcancer
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New research shows that specific co-mutations in KRAS-mutant non-small cell lung cancer may predict better response to ATR inhibitors. Read more: spr.ly/60144IbWM #LungCancer #EndCancer
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Kenn Samala retweeted
how the "30" era started how it ended
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Kenn Samala retweeted
Sa kasalukayan, mayroong 377 medical oncologists sa Pilipinas. Ang isang medical oncologist ay isang dalubhasa sa early detection, prevention, diagnosis at treatment ng cancer. Find a medical oncologist near you: bit.ly/findacancerexpert #cancerexpertsph #PSMO
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Dr. Tanasombatkul, a 29 y/o doctor with stage 4 #lungcancer shares that he does not have much time left. He wants others to know “Everyone can get this bc the world has become abnormal, with air & water pollution and various forms of radiation and our genes are ready to mutate"
Moral support has poured in for Dr. Krittai Tanasombatkul, with his hashtag “Don’t give up” (#สู้ดิวะ) top trending on X today, after he updated his condition as he suffers with his terminal lung cancer, saying he may succumb to the disease in the middle of December. Read more: thaipbsworld.com/moral-suppo… #ThaiPBSWorld #ThailandNews #ThailandUpdate
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“Cancer is responsible for 1 in 6 deaths globally. LMICs will account for the largest number of cases, making research that drives policies to help these countries even more critical” @WHO
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Come to see our 148 PDX collection resistant to innovative treatments. Ludovic Bigot. @GustaveRoussy #AACR23
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Impressive waterfall plots for SHR-A1811 in HER2+ and HER2-low MBC. Responses observed at all dose levels and in patients receiving prior HER2 ADCs. #AACR23
Jaw-dropping may be a better adjective. ORR 81.5% (88/108) in HER2+ MBC, 55.8% in HER2-low MBC (43/77). The wave of Topo1-ADCs is rising 🌊 eppro02.ativ.me/web/page.php…
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The most controversial meta-analysis of the year is now published on @TheLancet. Anthracyclines improved outcomes when added to adjuvant taxanes, but only when administered concurrently. No apparent benefit for sequential schedules, which are current SoC. thelancet.com/journals/lance…
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Improvement of 3-year EFS from 43% to 58% with only 3 neoadjuvant infusions of nivo added to neoadjuvant CT for NSCLC. Quite impressive.
#ELCC23 Neoadjuvant nivo+platinum-doublet ChT for resectable NSCLC: 3y update from CheckMate 816 Presented by dr @nicogirardcurie 3y EFS➡️57 vs 43% (HR:0.68) 💥Neoadjuvant N+C continues to provide long-term clinical benefit vs C in pts with resectable NSCLC @OncoAlert @myESMO
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🔥 HUGE news in breast oncology. The #NATALEE phase 3 trial of adjuvant ribociclib for stage II-III breast cancer met the primary endpoint of iDFS! novartis.com/news/media-rele…
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Kenn Samala retweeted
Important article for all breast oncologists to read, and a roadmap for efforts to improve/manage QOL @OncoAlert
thank you Matteo. Three trajectoires of global fatigue, including 19% patients "deteriorating". As always, endocrine therapy is a major parameter associated with fatigue, together with BMI and age (tables below are extracts, not the full table)
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Kenn Samala retweeted
🚨#Amivantamab has been approved by @Swissmedic_ for adults with #NSCLC with activating EGFR ex20ins mutations, after the failure of platinum-based therapy! Amivantamab is the first targeted therapy for this subset of #NSCLC 🫁 Check out more ➡️ bit.ly/35SjiDD
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11. Lastly, treat your patients how you would want your own family member treated. #MedTwitter #ArtofMedicine #WordsMatter @tmprowell @marklewismd @tarasanftmd @l_schapira 8/fin
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