Asc Prof. of Medicine, Columbia University, views own. Pancreatic cancer, translational therapeutics, metabolism, systems, paracrine interactions. It all fits.

New York, NY, USA
Joined August 2018
ICYMI, the new issue of @CR_AACR is online and features the print version of the In Focus commentary #PancreaticCancer–Associated Fibroblasts: Where Do We Go from Here? aacrjournals.org/cancerres/a… By Eileen Carpenter, @DebVendramini @MC_Hasselluhn @MaraShermanLab @Pasca_Lab @ednacukierman @KenOliveLab
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Revolution Medicines has launched its ph 3 study of RMC-6236 (RASolute 302) in patients with previously treated #PancreaticCancer. 1:1 randomization against physician’s choice of chemotherapy. A registration trial for KRAS inhibitor in pancreatic cancer! clinicaltrials.gov/study/NCT…
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KenOliveLab retweeted
There is a new tool on BioIcons to turn any protein (in PDB format) into a 2D vector illustration in SVG format. You can upload any PDB file or import from PDB, AlphaFoldDB or ESMFoldDB. Feedback welcome :) bioicons.com/pdb2vector/
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We are thrilled to welcome Michel Sadelain, MD, PhD, a global pioneer in CAR-T therapies, to Columbia and the HICCC.
Columbia welcomes CAR-T pioneer Michel Sadelain, MD, PhD, as the inaugural director of the new Columbia Initiative for Cell Engineering and Therapy and director of the Cancer Cell Therapy Initiative at the Herbert Irving Comprehensive Cancer Center. ➡️columbiamed.link/3zCR9iI
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KenOliveLab retweeted
I am excited to see this story by my talented Master's Student, Kristina Høj. Her research dives into age-related decline in pancreas regeneration and how it’s linked to a proinflammatory response to injury. @AGA_GHAdvances,@UCPH_BRIC, tinyurl.com/4e2uz2sb
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New online perspective article @CR_AACR article timed with the ongoing #PancreaticCancer stroma session at #AACRPan24 Pancreatic Cancer-Associated Fibroblasts: Where do we go from here? A conversation with three experts on the PDAC stroma (@MaraShermanLab @ednacukierman & @Pasca_Lab) led by three fantastic early career faculty (@MC_Hasselluhn @DebVendramini & Eileen Carpenter @UMICHpancreas). Lots of great perspectives on this complex subject! aacrjournals.org/cancerres/a…
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KenOliveLab retweeted
Congratulations to CU-DLDRC Associate Director, Timothy Wang, MD, who is the new Vice Chair for Academic Programs for the Department of Medicine at the Vagelos College of Physicians and Surgeons! Dr Wang will add this new role to his portfolio effective September 3rd, 2024.
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Replying to @NwosuLab
@NwosuLab @CornellMBG has opened a call for postdoc applicants. Please kindly repost and or forward to potential applicants. Job posting: academicjobsonline.org/ajo/j… Lab website: nwosulab.com
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On the topic of RNA-guided biology emerging from transposons, you won't want to miss this one! In published work led by the talented @TannerWiegand, we uncovered the presence of pervasive, RNA-guided transcription factors in diverse biological contexts. nature.com/articles/s41586-0…
Check out the latest story from the Sternberg group: phages coopted transposon-encoded nucleases (TnpB) and repurposed them for regulation of host genes! nature.com/articles/s41586-0… Thrilled to see this work in print, & a huge thanks to my amazing co-authors!!
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The long and winding road to drugging Kras: Channing Der shows the new possibilities in #PancreaticCancer research due to the discovery of Kras-targeting drugs. #CSHL
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An intense #PancreaticCancer fibroblast lecture by @MaraShermanLab lets us realize that there are many unknowns in this field. Are we breaking them down by cell of origin? Function? Or spatial arrangement?! #CSHL
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Our #PancreaticCancer patients not only suffer from the primary disease but also metastases in secondary locations. How can we study the mechanisms behind metastasis formation? @BenStanger01 keeps us up-to-date with the literature and his own lab’s experience. #CSHL
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KenOliveLab retweeted
KRAS Resistance, Mechanisms, and Therapeutics: Andrew Aguirre, Kenneth P. Olive, and Mallika Singh will address this topic in a plenary session at the AACR Conference on Advances in Pancreatic Cancer Research (Sept 15-18, Boston). bit.ly/4el6lAu #AACRpan24 @KenOliveLab
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Replying to @KenOliveLab
@KenOliveLab talks with Clinical Research News on the multi-institutional collaboration published in Nature on a pan-RAS inhibitor known as RMC-7977, developed by Revolution Medicines that offers hope of improved prognosis in pancreatic cancer. clinicalresearchnewsonline.c…
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The OPTIC core at HICCC is bringing #cancerresearch to life 🙌 Learn how our cutting-edge imaging instruments use #bioluminescence to show cancer in living models, illuminating crucial insights about cancer. #ncrm24 cancer.columbia.edu/research…
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New review from our group @cincysurgery @UCincyMedicine comparing and contrasting mutant-selective-, pan-KRAS, and RAS(MULTI)ON-selective RAS inhibitors in pancreatic cancer with standards of care: @SzuAunLongMD @SyedAAhmad5 @ambermamparo @grace_goodhart frontiersin.org/journals/onc…
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KenOliveLab retweeted
First corresponding author paper is now out describing our analysis of CCNE1-amplified esophagogastric cancer! Congrats to 1st author Naryan Rustgi. Great collaboration with @carisls POA aacrjournals.org/cancerresco…
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