@KyleKroll

MSc Bioinformatics. Researching alternative Fc signaling in NK cells. Opinions and tweets are my own and do not reflect my employer. He/him

 Boston, MA
orcid.org/0000-0002-9237-9497
Joined June 2019
  • Tweets249
  • Following107
  • Followers51
8Media
NK cells in healthy aging show increased ⍺4β7 & decreased CCR7, which is reversed in people living with HIV possibly due to recruitment to HIV lymphoid reservoirs or failed mucosal signaling @ReevesLabNK @KyleKroll doi.org/10.1016/j.xcrm.2022.…
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Has anyone else started using Git to track manuscript changes? I don't know why I didn't think of it earlier but a private repo is perfect for keeping a change history
My lab is actively expanding. If you have an interest in NHP models of HIV and other viral infections I encourage you to check out the listing. Our lab space is brand new and we are ramping up our studies
Reeves & Jost Lab@ReevesLabNK14 Oct 2021
The Reeves Lab, now of the Division of Innate and Comparative Immunology at Duke University, has an opening for a postdoctoral fellow. If you are a recent PhD with a passion for immunology and experience in flow cytometry, please see our job listing here linkedin.com/jobs/view/27535…
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The Reeves Lab is also looking for a Lab Research Analyst II / Immunology Lab Manager. If you have experience operating highly technical laboratory instruments and wish to conduct original immunology experiments, please see our job listing here. linkedin.com/jobs/view/27535…
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Does anyone in the #bioinformatics area have recommended readings for getting started with things like Snakemake, Nextflow, Docker, etc.?
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Final round of experiments done. Now to see if PI thinks it's enough to submit a grant
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Rhianna Jones and Dr. Cordelia Manickam in Dr. Keith Reeves' lab (@ReevesLabNK) analyzed the #granulocyte compartment in mucosal and lymphoid tissues of #lentivirus-infected macaques. This gave them insight into immune modulation and viral replication. 👉 bit.ly/2UhS9Ur
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Fever supports CD8+ effector T cell responses by promoting mitochondrial translation pnas.org/content/118/25/e202…

Fever supports CD8+ effector T cell responses by promoting mitochondrial translation | PNAS

Fever can provide a survival advantage during infection. Metabolic processes are sensitive to environmental conditions, but the effect of fever on ...

pnas.org
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Moderna results are out for their booster vaccines! 🔵 Boosting with same vaccine generates good antibodies against variant B.1.351 🔵 Boosting with a B.1.351 vaccine generates even better antibodies 🔵 Safe 🔵 The booster vaccine was made and tested with exceptional speed! 🧵
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Они обалдели! The Sputnik V vaccine Ad5 vector is evidently replication competent. The makers apparently neglected to delete E1, so getting this vaccine means being infected with live adenovirus 5. Hence Brazil’s regulator correctly rejected it. ctvnews.ca/health/coronaviru…
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Paper available here. authors.elsevier.com/a/1cxop… We show NK cell education matters. For reproduction. Star receptor is good old CD94:NKG2A
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CD94/NKG2A receptor educates maternal NK cells to orchestrate vascular changes leading to normal fetal brain development and, in humans, to lower risk of complicated pregnancy. @DrFran_Colucci cell.com/immunity/pdf/S1074-…
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fun little side project I am working on. I run our lab's website and one task is querying PMC for new publications so that they can be added to our website. Working on converting these scripts to a tidy UI so that others can use it as well. Running in Python + PyQt5
New NK cell KIR paper from the lab, in collaboration with Andrew Brooks and Julian Vivian. @MonashBDI @MoradiShoeib nature.com/articles/s41467-0…

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C

Nature Communications - KIR2DL2 and KIR2DL3 are two inhibitory members of the killer-cell immunoglobulin-like receptors (KIR) family that share a common HLA-I preference in binding HLA from the C1...

nature.com
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It's true and one of the reasons I don't actively use LinkedIn. I keep my profile updated and check job postings occasionally but that's about it.
Vega Shah
@dr_alphalyrae12 Apr 2021
Replying to @aarit_ahuja
Yeup. And LinkedIn is seriously 80% of this -
If you want to make six figures overnight have you ever tried being a grad student???
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Does anyone know of commercially available monoclonal antibodies with IgA isotype? Looking specifically for CD3 and/or CD4 antibodies, thanks!
The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation dlvr.it/RvbJHQ

The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation -...

Epigenetic landscapes can provide insight into regulation of gene expression and cellular diversity. Here, we examined the transcriptional and epigenetic profiles of seven human blood natural killer...

pubmed.ncbi.nlm.nih.gov
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The three most important things in data analysis are exploratory data analysis, exploratory data analysis, and exploratory data analysis.
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Hi Everyone. One of my dissertation students is really struggling for participants to take part in her online survey on the impact of working from home vs working from an office. If you can help, please click on the link! Thanks 😊 #wellbeing #engagement loughboroughssehs.eu.qualtri…
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