The peer-reviewed version of our manuscript describing the structure of NRP2-bound HCMV Pentamer is now available @ScienceAdvances!
science.org/doi/10.1126/scia…
New preprint just dropped! We report the hi-res structures of the HCMV Pentamer bound by host receptor NRP2 and four neutralizing mAbs. Some very cool insights into one of the earliest stages of cytomegalovirus infection. Many thanks to all involved!
biorxiv.org/cgi/content/shor…
Replying to @BarneyGrahamMD @McLellan_Lab
A message from myself to Dr. Nianshuang Wang (@goodwish916) on January 30th, 2020. Using the same plasmids that he made and shipped to the VRC, we purified our stabilized spike protein and finished collecting the first cryo-EM structure of the SARS-CoV-2 spike one year ago today
Playing around with DeepEMhancer to reduce map artifacts in this C3 reconstruction. Thanks to @1avier and @CosmicCryoEM for making it so accessible!
Happy to share our recent publication with the An Lab from @UTHealth, out now in @PLOSPathogens!
journals.plos.org/plospathog…




