Structural biologist specializing in host-pathogen interactions
Joined June 2020
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Daniel Wrapp retweeted
Can we leverage recent developments in machine-learning & protein design to tackle previously intractable challenges?
The answer is yes and we show it in this study led by the one and only @Dr_MattMcCallum
@HHMINEWS
@UWBiochemistry
1/9
biorxiv.org/content/10.1101/…
Daniel Wrapp retweeted
Check out our pre-print describing a CCHFV glycoprotein complex in the pre-fusion conformation! We used several engineering tricks to design our final construct, GP38-GnH-DS-Gc. Great collaborative effort, led by graduate student @Eliza4Science! biorxiv.org/cgi/content/shor…
Daniel Wrapp retweeted
My group at @ISTAustria is recruiting a lab manager/research technician to join when we start in July! If you're passionate about science and thrive in a dynamic environment, apply here: ista.ac.at/en/job/?title=Res… #ResearchJobs #LabManagement #ScienceCareers
Daniel Wrapp retweeted
Excited to share the pre-print describing our efforts to stabilize the HCMV gB ectodomain in a prefusion-like conformation. We and others have now routinely stabilized class I viral fusion proteins, but class III viral fusogens have been more difficult.
Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation biorxiv.org/cgi/content/shor… #bioRxiv
Daniel Wrapp retweeted
My Department (Biochemistry, Microbiology and Bioinformatics @ Université Laval) has 2!! tenure track positions open: one in viral ecology and one in microbial functional genomics. Awesome place to start your new lab and wonderful colleagues! 😉 Get in touch if interested. 🦠🤓
Well deserved!! Congratulations @McLellan_Lab !
The winner of the 2023 NAS Award in Molecular Biology is Jason S. McLellan of @TexasScience! He is being honored for pioneering work in the molecular and structural biology of viral surface proteins. Learn more: bit.ly/3Xu5GnF #NASaward #MolecularBiology
Very happy to share the peer-reviewed version of our manuscript, available now ahead of print with open access at @JVirology ! Wonderful collaborative effort with my colleagues here @TheDHVI
journals.asm.org/doi/10.1128…
Our preprint has been released on bioRxiv! Details a new stabilization strategy that should be a useful tool for researchers trying to produce tricky HIV Env proteins. Great collaborative effort from @DHVI_Struc_Bio @lab_haynes @TheDHVI
biorxiv.org/content/10.1101/…
Daniel Wrapp retweeted
Delighted to have my 1st first-author paper @CellReports!
High-res site Ø and V complexes. Plus, now includes structural mapping of two non-canonical sites at the trimer interface, which are preF targets but elicit low neut mAbs. Thanks to all involved! cell.com/cell-reports/fullte…
Daniel Wrapp retweeted
Come work with us! We are hiring a lab manager to support our team investigating a broad spectrum of emerging and re-emerging viruses and developing vaccines & therapeutics!
Please RT and pass the word as widely as possible.
