Macro Alchemy (@MacroAlchemy) header
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Markets, RWA, AI | Macro strategy. Technical, fundamental & quantitative analysis. Narratives, signals, data. Deep dives & theses. Reports worth bookmarking!

Joined September 2009
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Macro Alchemy retweeted
Millennials: The Rug Pull Generation. Study hard and you'll get a good job. 2008 financial crisis. Work hard and you'll own a home. Housing crisis. Build a career and enjoy stability. Gig economy and layoffs. Enjoy your prime years. Global pandemic. Save for your future. Inflation. Finally, AI might free us from working our lives away. Potential World War III.
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You have 11 open tabs He has 11 open labs
SITUATION DETECTED: Anthropic acquired a one-person company in July 2026. Mithril Medicine - developing treatments for two rare forms of muscular dystrophy - owned and run by one person who used Claude to organize contracts, logistics, and experiments with 11 external labs.
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Macro Alchemy retweeted
bro AI is solving millennium math problems and you think it can't do software architecture
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Their business model is simple. Their vision too. Immortal, divine, eternal, interplanetary, galactic. Not selling subscriptions to cattle.
Over the past few months, Anthropic scientists have engaged in deep research partnerships with six organizations developing new medicines. We've also begun drug discovery efforts of our own. In doing so, we’ve learned much more about how Claude can support the many stages of drug development. In this blog post, we share some early results from these efforts, and describe how this work fits in with our wider ambitions in the life sciences. anthropic.com/research/early…
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Macro Alchemy retweeted
openai's internal model still has not produced a single result in gender studies
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Macro Alchemy retweeted
This is getting insane. 🤯 CrowdStrike’s CEO says AI is now allowing low-skill hackers to pull off cyberattacks that once required nation-state-level resources. All for the cost of a few tokens and a prompt. The barrier to entry is collapsing. And we’re only getting started.
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Macro Alchemy retweeted
We obviously haven’t had the major jobs wipeout yet. But you read stuff like this. And you read what economics students themselves are saying about working with AI (ht @odavis_h) and it’s hard not to feel like the seismic shift is on its way.
Replying to @Neil_Irwin
He goes so far as to say that if he were to run the White House CEA today he'd do it with a lot of reliance on Claude and friends.
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Macro Alchemy retweeted
If you're not in AI and need to understand what's happening: This year we've went from Super Nintendo to PS5 in 6 months
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I think I have a good analogy for what's about to happen in cyber. It's pitch dark. Always has been. And the world is dilapidated buildings and rats and maggots and other creepy-crawlies. The whole world. And we just invented flashlights.
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That's why analysts judging how much these companies make from subs and their APIs is meaningless. Although I also said something a few months ago. AI is driving its own demand. Demand for cyber defense, for a problem AI itself has created.
As the gap between the internal models at the AI labs and the ones they release grow (due to safety concerns & research advantages), it will be increasingly tempting for OpenAI & Anthropic to exploit that advantage directly by entering new markets, especially in finance & biotech
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Macro Alchemy retweeted
Opus 5.5’s controversial take about humans
Controversial take from Gemini 4 Argon
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Macro Alchemy retweeted
a lot of old software was protected by “exploiting this would be an unreasonable amount of work” we have invented a machine that does unreasonable amounts of work anyway how’s the patch backlog
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Macro Alchemy retweeted
I getting a feeling that OpenAI and Anthropic soon will ditch customers completely, just use their models 100% internally and go all in on frontier science and engineering research Like eg if they actually solve quantum gravity or cure cancer, and own the right to license the solution, can you imagine the ROI behind that? No more listening to users bitching about usage or model nerf or whatever
Dr. Christopher Stubbs is joining our Long-Term Benefit Trust. Chris is an experimental physicist and a former Dean of Science at Harvard University. He has also advised the US government on national security and arms control. Read more: anthropic.com/news/christoph…
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This, but without the illusion of democracy. Governments don't care about us. At least in the west, they really hate us. China is treating its citizens much better, compared to how the western governments are treating their citizens... and it's not a democracy.
The Intelligence Curse is happening TLDR: When AIs make humans economically useless, governments and corporations have no incentive to invest in their people For centuries, normal people could withhold their labor to negotiate. That era is almost over. This breaks democracy - politicians won't need the support of the people - and leads to severe concentration of power
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youtube.com/watch?v=Rqt9kWoT… These people are evil and are coming for us. Unfortunately, most of us, if not all of us... are cattle about to be sacrificed to their Gods. Within the next few months they will throw everything at us. War, famine, cyberattacks... everything.
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Macro Alchemy retweeted
what I've learned from this post is that almost no one is AGI-pilled and that they don't take seriously the possibility of tens to hundreds of millions of AIs working 24/7 at 10–100x human speed
Surveyed Anthropic staff's answers imply 17.1% GDP growth in 2030
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Macro Alchemy retweeted
Few months ago Mythos could only find a single vulnerability in curl repository, now it basically became a CTF. What has changed? Better models? No. Better harnessing and steering by subject matter experts.
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Macro Alchemy retweeted
They tell you what they're going to do before they do it. Prior to Covid in 2019 they ran a simulated pandemic exercise in 2017 called the SPARS pandemic.
JUST IN: G7 nations agree to launch simulated AI-powered cyberattacks on financial systems to test their defenses.
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When you look at all the statistics by Anthropic, it's clear that they will have reached RSI by the end of Jan. One could say they are already there. Their models already help build big part of their models and software. Opus 5.5 is 5 months behind where Anthropic is internally
Anthropic has singlehandedly compressed RSI timelines by about a year.
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Macro Alchemy retweeted
Kospi dumped so hard that president posting dont die
살아야지요. 어떻게든 사셔야 합니다. 힘드시면 109번 전화를 하십시오. 사실 길, 살아야 하는 이유를 함께 찾아드릴 것입니다.
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