@MakelaJarno

Assistant Professor of Biophysics at Aalto University | Temperature adaptation | Super-resolution microscopy | Single molecule tracking

 Helsinki, Finland
aalto.fi/en/department-of-neuroscience-and-biomedical-engineering/single-molecule-dynamics-in-cells
Joined November 2019
  • Tweets352
  • Following281
  • Followers484
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We are looking for a postdoc with microbiology background for #superresolution #singlemolecule #ERC tracking project. Apply by 27.4.2025. 🦠🔬🧫 Pls share! aalto.fi/en/open-positions/p…
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I have PhD and postdoc positions available in our lab to explore mechanisms of ER protein biogenesis and homeostasis and small molecular modulation, please RT. Expertise in biochemistry, chemical biology and structural biology (especially cryo-EM and cryo-ET) beneficial!
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Matthew Swaffer@mpswaffer30 Sep 2024
We’re hiring! We have Wellcome-funded postdoc positions to join my group. The project will build on recent work on transcriptional cell size scaling (Swaffer et al. Cell 2023) to ask how gene expression, RNA metabolism and cell signalling are all coordinated with cell size (1/3)
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📢Job Alert!📢 We are looking for 2 PhD students with biophysics or computational biology background for #SuperResolution #singlemolecule tracking project. More information: tinyurl.com/5b58y9kd Apply by 31.10.24. 🦠🔬 Pls RT!
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Mathew Stracy@M_Stracy20 Sep 2024
We're recruiting a postdoc! Project focused on the molecular and evolutionary biology underpinning antibiotic tolerance. Come join us @Dunn_School @UniofOxford See here for details and to apply: my.corehr.com/pls/uoxrecruit…
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We are happy to announce that we have a new research team! They explore bacteria that thrive in extreme conditions. Welcome onboard Assistant Professor @MakelaJarno and team: @Aakeel24, Taras Redchuk, Dan Noel, Eveliny Nery, Ada Pajari and Chris Hayes! aalto.fi/en/news/off-to-a-fl…

‘Off to a flying start’ – a new research team explores bacteria that thrive in extreme conditions |...

Jarno Mäkelä joined Aalto’s Department of Neuroscience and Medical Engineering as Assistant Professor of Biophysics in early September, together with research fellow Taras Redchuk, postdoctoral...

aalto.fi
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I'm excited to share that I have started as an Assistant Professor @AaltoUniversity #NBE. Big thanks to all colleagues and friends from @BIOTECH_UH @helsinkiuni and everybody else who has helped and supported me on the way. Stay tuned for open positions!
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Our work on cytoplasmic fluidization during germination of fission yeast spores is finally published in PNAS! Congrats to @Keiichiro_Sakai , @KondohYohei , and @goto_yuhei ! pnas.org/doi/10.1073/pnas.24…
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Jette Lengefeld@JetteLeng13 Jun 2024
💥Postdoc and PhD positions open for highly motivated enthusiast of hematopoietic stem cells at Helsinki University @BIOTECH_UH @HiLIFE_helsinki in the happiest country of the world: Finland 🇫🇮 Link here: lengefeldlab.com Please RT 🙏 We are excited for your application!😃
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Amy Moores@amy_moores12 Jun 2024
Using live-cell single-molecule tracking for your experiments, but not sure which fluorescent label to use? Our new study might help! pubs.acs.org/doi/10.1021/acs…

Robust Quantification of Live-Cell Single-Molecule Tracking Data for Fluorophores with Different...

Abstract. High-speed single-molecule tracking in live cells is becoming an increasingly popular method for quantifying the spatiotemporal behavior of prote

pubs.acs.org
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Great news! Jane and Aatos Erkko foundation has granted funding for our mitochondria super-resolution collaboration project with Uwe Richter @rs_mito. Thank you! @LifeSciHelsinki @AaltoUniversity
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Single-Molecule Bacteriology III is approaching! See how the latest microscopies, probes, fluidics, and data analysis transform our grasp of bacterial mechanisms. Great speakers + 20 slots for talks from the Abstracts (submit by July 30). Join us! eventsforce.net/biochemsoc/f…
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Jenal_lab@JenalLab10 May 2024
Our c-di-GMP sensor story is finally out in @NatureComms: rdcu.be/dHsEh. Including new data demonstrating cdGreen2 as a convenient tool to study DGC and PDE activity in vitro. Great collaboration with @simon_vanvliet and @MaierLab!
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A library of reporters of the global regulators of gene expression in Escherichia coli @mSystemsJ from @AndreSR_Lab journals.asm.org/doi/10.1128…
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Michael Fischbach
@mfgrp11 Apr 2024
How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/S0092…

Problem choice and decision trees in science and engineering

Scientists and engineers often spend days choosing a problem and years solving it. This imbalance limits impact. Here, we offer a framework for problem choice: prompts for ideation, guidelines for...

cell.com
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Chase Broedersz@CBroedersz6 Apr 2024
🔥new mini-review 🔥 lead by Janni Harju on physical modelling of bacterial chromosomes 🧬 now out in Molecular Microbiology! what can polymer physics, bottom-up modelling, and data-driven approaches teach us about prokaryotic chromosome organization? 👉doi.org/10.1111/mmi.15257

Physical models of bacterial chromosomes

Connecting experimental observations to biophysical models can give rise to new insights on bacterial chromosome organization. Simple polymer models explore how physical constraints affect bacterial...

onlinelibrary.wiley.com
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Hey everyone - Pls RT - we’ve got a great position open for a talented #postdoc scientist to join us @HiLIFE_helsinki @helsinkiuni to study the spatial organization of #metabolism in #intestinal #stem cells and #cancer! Interested? Just get in touch. Apply by the 4th of May aka Star Wars Day 😃 nature.com/naturecareers/job…
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ShorterLab@ShorterLab2 Apr 2024
Single molecule tracking reveals nanodomains in biomolecular condensates biorxiv.org/content/10.1101/…

Single molecule tracking reveals nanodomains in biomolecular condensates

Protein-rich biomolecular condensates formed by phase separation[1][1] play a crucial role in cellular RNA regulation by the selective recruitment and processing of RNA molecules[2][2]. The functio...

biorxiv.org
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Miloš Tišma@TismaMilos29 Mar 2024
Second: We removed the SMC proteins via a clever Knock-down mutant created by @Gruber_Lausanne , and observed that the chromosomes gradually open up into a toroidal/donut shape… SMCs are the sole factor holding this megabase chromosome in the crescent shape🤩 9/13
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We are excited about the publication of our latest paper showing how tuning the Hsp90 protein folding system drives multicellular evolution by revealing novel developmental phenotypes: science.org/doi/10.1126/scia…
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