I was asked to give a lecture next week at a church in Minnesota on what I see as the most pressing issues facing Christians. Here's my rundown I'm working on for my lecture. — The beginning of life: Reproduction and human dignity. — The manufacture of life: Genetic engineering and designer children. — The simulation of life: Artificial intelligence and digital personhood. — The enhancement of life: Transhumanism and human augmentation. — The embodiment of life: Biological sex and bodily identity. — The commodification of life: Surrogacy and reproductive markets. — The manipulation of life: Surveillance, algorithms, and human agency. — The extension of life: Longevity and the pursuit of immortality. — The quality of life: Disability, dependency, and the meaning of dignity. — The end of life: Assisted suicide and euthanasia. In a word: bioethics. The central moral question of our age is increasingly whether human nature is a gift to be received, enhanced beyond our native capacities, or a problem to be solved. Christians need to be prepared to answer it. I am confident that our doctrine of the imago Dei, coupled with the Christian natural law tradition, provides a sufficient basis and bulwark to guide civilization, if civilization will entertain them.