Solvitur ambulando - Biosynthesis; pathway engineering; enzyme discovery-structure-mechanism; biocatalysis & nucleic acids.

Imperial College London
Joined June 2018
Micklefield Lab retweeted
#grabstract of the day Scientists engineered enzymes to add sugars to antifungal drugs, making them more powerful against deadly fungal infections while reducing harmful side effects for patients. doi.org/10.1038/s41586-026-1…
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Micklefield Lab retweeted
Our lab’s latest on synthetic genomics “Synthetic Combinatorial Minimisation of Cell Cycle Control” is up now on BioRxiv - covering ambitious yeast #synbio cell cycle work led by Anastasiya Malyshava and co-supervised by @UniOfSurrey’s Matteo Barberis.
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Micklefield Lab retweeted
🚨New research from the @Micklefield_Lab. The team have uncovered a new class of antifungal agents that are more effective and less toxic than existing treatments. Read the full story: imperial.ac.uk/news/articles…
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🎉 We’ve done it again! We've secured our 3rd consecutive #AthenaSwan Gold Award 🏅 Dr Nazila Kamaly shares how allyship, adaptability & community spirit keep inclusion at our core 💛 Read the Q&A 👉 imperial.ac.uk/news/articles… #EDI #STEMinclusion #ImperialChem
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Micklefield Lab retweeted
Welcome to the Department Joe! Very much looking forward to you joining our community @JosefBoronski
Please join us in welcoming @JosefBoronski who joins us in February 2025 as a Lecturer at the Department of Chemistry @imperialcollege. See you soon! @ MSRH @WCIDLondon @ImperialSci @RoySocChem @imperialcollege #chemistry
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Please join us in welcoming @Micklefield_Lab who today has joined the Department of Chemistry @imperialcollege. We are super excited to have you become a member of our community @ MSRH @WCIDLondon @ImperialSci @RoySocChem #chemicalbiology @icbcdt @ImpEngineering @ImperialIdeas
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Peptides are important for medicine production, but they are currently made via unsustainable methods. @Micklefield_Lab have found a brand new enzyme that produces peptides more efficiently. This could be used to treat many diseases including cancer. manchester.ac.uk/discover/ne…
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Seven leading Manchester researchers are being awarded highly prestigious @ERC_Research advanced grants, designed to provide research leaders with the opportunity to pursue ambitious projects that could lead to major scientific breakthroughs. manchester.ac.uk/discover/ne…
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🎉We are please to announce that @Micklefield_Lab have been awarded an @ERC_Research Advanced Grant. They will be investigating new and more sustainable ways to produce peptides which are essential in many medicines, vaccines, and biomaterials. manchester.ac.uk/discover/ne…
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Micklefield Lab retweeted
Next up, @RoySocChem Organic Division President Prof. David O'Hagan of @univofstandrews bestows the Interdisciplinary Prize for 2022 to Prof. Jason Micklefield @Micklefield_Lab of @UoMChemistry. Many congratulations!
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We have a fully funded 2023 entry CDT studentship available: MRes at @IC_CSynbBio followed by 3yr PhD at @UoMMIB with @Micklefield_Lab Engineering microbial cell factories for production of improved anti-infectives. Info here imperial.ac.uk/synthetic-bio… Deadline Monday 17th July!
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Congratulations to the Enzyme Discovery team based at @UoMMIB, who won the Chemistry Biology Interface Horizon Prize: Rita and John Cornforth Award, for its work investigating enzymes to combat antimicrobial resistance in the developing world...
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Micklefield Lab retweeted
1st table tennis🏓️ tournament of The Manchester Institute of Biotechnology @UoMMIB. The @Micklefield_Lab group won first and second place😁.
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Micklefield Lab retweeted
Spoilt at the moment for natural products seminars @JohnInnesCentre, with @marnixmedema last week and @Micklefield_Lab this week. Thanks a lot for visiting! @micronorwich on Thursday as well 🦠💊
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Micklefield Lab retweeted
Another rising star Dr @WeiliThong1 from the @Micklefield_Lab @UoMMIB presents her project on antibiotic biosynthesis engineering in Streptomyces before she leaves for her new job in industry. – at Manchester, England
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Micklefield Lab retweeted
See what a typical day @UoMChemistry looks like. Meet members of @Micklefield_Lab group planning, executing and presenting their exciting research! youtube.com/watch?v=qwvvTEa0… #uomchemistry
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