Imaging Scientist in @celljxn
Hershey, PA
Joined October 2017
- Tweets528
- Following412
- Followers419
- Likes932
Will Giang 🔬 retweeted
Excited to share our new pre-print showcasing tools (chemical & optogenetic) for repositioning #vimentin in cells! Movie shows #ER (Halo-KDEL) sheets being relocalized together with vimentin (Vim) upon local vimentin pulling in U2OS. @gijsjekoenderi1
biorxiv.org/content/10.1101/…
Apply to be the manager of a light microscopy core at Penn State College of Medicine in Hershey!
psu.wd1.myworkdayjobs.com/PS…
Will Giang 🔬 retweeted
Happy to share my cofirst-authorship in this work about my phD project👩🏻🔬.
We developed new reversible reporters to detect the dynamics of #MembraneContactSites and their associated #calciumsignaling.
Enjoy your read ⤵️ and our colourful pics & movies🎦.
nature.com/articles/s41467-0…
Will Giang 🔬 retweeted
Pleased to present our latest work, where we show that the cell-cell adhesion protein afadin coopts mechanically-regulated elements of the cadherin-catenin complex to drive cytoskeletal engagement. biorxiv.org/content/10.1101/…
Will Giang 🔬 retweeted
Which monomeric GFP is the brightest and most photostable?
A winner has just been announced, and it is mStayGold from the Miyawaki lab, edging out two other monomeric StayGold candidates.
biorxiv.org/content/10.1101/…
Will Giang 🔬 retweeted
We developed a new super-stable RFP for advanced microscopy, like CLEM, Rapid tissue clearing, Live 3D-SIM and live STED.
Read this #preprint on @researchsquare: mYongHong: a structure-guided design of stable and monomeric red fluorescent protein researchsquare.com/article/r…
Will Giang 🔬 retweeted
Out at @naturemethods just now!
nature.com/articles/s41592-0…
We present #SN2N, a flagship level unsupervised denoising solution. It’s fully competitive with supervised learning without needing large training-set and clean ground-truth, using 1 noisy frame for training.
(1/n)
Will Giang 🔬 retweeted
Let me introduce: InstanSeg 🦠🔬💻👩🔬
This *would* have been a short thread about Thibaut Goldsborough’s PhD work… but he solved too many problems.
Now it's a long thread about 2 preprints, a whole new approach to cell segmentation & #opensource software to make it easy to use
Will Giang 🔬 retweeted
BioRender updated their terms and, oh yes, I'm sure journals will be *thrilled* to print hyperlinks direct to BioRender's website at the bottom of figure legends.
help.biorender.com/hc/en-gb/…
Will Giang 🔬 retweeted
Long awaited (thanks @JamesDManton for posting the patent application!) and now out in @ScienceMagazine: Using absorption to look deeper by @HongNeuroTech - they achieved approx. 3 mm depth using the food dye tartrazine: #Microscopy
science.org/doi/10.1126/scie…
Will Giang 🔬 retweeted
Scientific colour maps: yes!—But when and what not to do with them?
👉doi.org/10.1002/cpz1.1126
including resources for researchers, science communicators, software developers, publishing editors, and University faculty!
@ShepGracie @philipheron
#DataVisualisation
#UseBatlow
Will Giang 🔬 retweeted
(1/x) We are excited to introduce VIPS (Volumetric Imaging of biological specimens via Photochemical Sectioning) in our preprint! VIPS uses a light-based process called “photochemical sectioning” to achieve petabyte-scale high/super-resolution imaging: biorxiv.org/content/10.1101/…
Will Giang 🔬 retweeted
We present:
'Multispectral live-cell imaging with uncompromised spatiotemporal resolution'.
biorxiv.org/content/10.1101/…
1/16
Will Giang 🔬 retweeted
The new mitochondrial probe PKmito ORANGE FX in now available!
✅ Optimized for PFA or GA fixed cell mitochondria imaging
✅ Highly suited for STED imaging
✅ Compatible with immunostaining and CLEM
spirochrome.com/product/pkmi…
Order it now from our distributors and take advantage of the 30% introductory discount.
Read more about PKmito ORANGE FX in the PNAS article by @ZhixingChen2 pnas.org/doi/full/10.1073/pn…
Will Giang 🔬 retweeted
Exciting preprint from the awesome folks (Mavrakis & Brasselet group) at @InstitutFresnel on new fluorescent reporters that will allow for polarisation measurements (in addition to regular microscopy) of actin dynamics in live cells!This is a big deal!
biorxiv.org/content/10.1101/…
Will Giang 🔬 retweeted
After countless requests, we're thrilled to introduce PK Mito Orange FX - a fixable variant of PKMO. PKMO FX allows immunolabeling and CLEM approaches.
Happy to have contributed to this project led by @ZhixingChen2 and Christian Jüngst.
#mitochondria
pnas.org/doi/10.1073/pnas.23…
Will Giang 🔬 retweeted
Insane! My favourite figure, 21 targets labeled in one image! Multiplexing is now offered with 3 flavours: Optoplex, Enziplex and Chemiplex, relatively easy to adapt at your labs.
Great work!
Very happy to see the central Ph.D. topic (out of several) of @N_Mougios in @biorxivpreprint. He established a universal way to make all your antibody-based assays easily multiplexable by using erasable secondary #nanobodies. See it here: biorxiv.org/content/10.1101/…
Will Giang 🔬 retweeted
Our (news&) views on new monomeric StayGold variants can be accessed here: rdcu.be/dBbnS
I hope you enjoy reading it!
Will Giang 🔬 retweeted
#Cellpose 3! Not all images are perfect. Restore your images with Cellpose3 to get better segmentations, w/ @marius10p biorxiv.org/content/10.1101/…