Noam Nago retweeted
๐งตNew preprint! How does an elongating RNA polymerase deal with a DNA-bound transcription factor in its path?
We developed a label-free single-molecule assay that detects RNAP arrival by suppression of fluctuations in a partially unzipped DNA fork.
biorxiv.org/cgi/content/shorโฆ
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I'm trying to win a DS-11 FX+ Spectrophotometer / Fluorometer from @denovix, recipient of the SelectScience Diamond Seal of Quality! denovix.com/diamond #DeNovix #DiamondDS11
Noam Nago retweeted
๐งต
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New preprint!
How do transcription factors (TFs) use intrinsically disordered regions (IDRs) to find their target sites?
biorxiv.org/content/10.1101/โฆ
#TranscriptionFactors #IDPs #SingleMolecule #Biophysics
Noam Nago retweeted
Postdoctoral fellowships from the Azrieli Foundation.
Join us to use cutting-edge single-molecule biophysics to study transcription regulation!
azrielifoundation.org/the-azโฆ
Noam Nago retweeted
How gene transcription works. DNA to RNA:
#biology by D. Berry
Noam Nago retweeted
**ืื ืืืืช ืกืคืจื ื** ืกืื ืืืื ืืื ืืืฆื ืืืกืจ ืชืืืื ืื ืืฉืืขื ืืกืืืื ืืื/ืืช ืืขืืืื/ืืช ืืืื ืืื, ืชืืื ืืชื, ื ืืืืชื ืืืื ืืช ืืืืืชื ืืืืืจืืช ืืฉืจ ืชืืื ืืืชื ืืืื ืืืคืฆืช ืฉื ืื, ืืืจืจืืื ืืืจื ืืืืคืจืื ืืืืจืืช .
drive.google.com/file/d/1nl8โฆ
Noam Nago retweeted
Interested in single-molecule methods to study #chromatin dynamics and #transcription?
We have a #postdoc opening in the lab, and the Zuckerman Postdoctoral Fellowship is an excellent opportunity.
zuckerman-scholars.org/ourprโฆ
For more info: kaplan.net.technion.ac.il
Noam Nago retweeted
During nucleosome passage, Pol II causes loss of H2A-H2B dimers from the nucleosome, resulting in hexasome formation. We provide structural evidence for this process and observe that Pol II backtracks upon encountering nucleosomal barriers @MolecularCell.
authors.elsevier.com/c/1fRPaโฆ
Noam Nago retweeted
How do ATP molecules rapidly reach their catalytic sites in the ultrafast helicase RecBCD?
Our new publication, in collaboration with Arnon Hennโs and @KleifeldO, is now out in @NatureComms:
โAuxiliary ATP binding sites support DNA unwinding by RecBCDโ 1/n
nature.com/articles/s41467-0โฆ
Noam Nago retweeted
ืื ื ืืืฉื ืฉืื ืื ื ืื ืืขืจืืืื ืืกืคืืง ืืช ืืฆืจืคืชืื ืขื ืื ืฉืืืจ ืืืคื 7 ืฉืขืืช ืืคืชืืืช ืืืืืื ืืื ืขืืืื ืื ืืืืืขื ืขื ืื ืืขื
Noam Nago retweeted
Single molecule characterization of the binding kinetics of a transcription factor and its modulation by DNA sequence and methylation academic.oup.com/nar/advanceโฆ Congratulations @Hadeel_Khamis8!
Noam Nago retweeted
Extended and dynamic linker histone-DNA Interactions control chromatosome compaction dlvr.it/S5xqB8
Noam Nago retweeted
Interested in a postdoc in our lab, studying nucleosomes, transcription factors, and polymerases with cool single-molecule methods?
The Fulbright postdoctoral fellowship is open for applications.
fulbright.org.il/program/2/3โฆ
Please RT
Noam Nago retweeted
Principles of 3D compartmentalization of the human genome dlvr.it/S2qFFn
Noam Nago retweeted
- How to characterize the full distribution of binding and dissociation times of unlabeled transcriptions factors?
- How do DNA sequence and methylation affect these kinetics?
Our new work, leaded by @Hadeel_Khamis8 , is out
biorxiv.org/content/10.1101/โฆ
Here is a short thread:
Noam Nago retweeted
ืื ืฉืืชื ืจืืืื ืืื ืืกืื ืืงืืืืื ืืืืจืชื ืืืื ืืืชืจืืฉ ืืื ืขืื ืื ื. ืื ืืืืืืช ืคืืจืงืช ื ืคื ืื ืื ืงืฆ"ืื, ืืืืืช, ืืืืงืจ (ืชืืื ื- @RedseaPlankton ืขื ืืฆืืืื). ืืชืืื ื ืฆืืืื ื- 200 ืืืจ ืืฉืืืจืช ืืืืืืืื.
Noam Nago retweeted
What you see in this picture is an ecological disaster waiting to happen. It is a tanker unloading oil at Eilat, at the northern tip of the Red Sea, and 200m from the coral reef reserve (photo by @RedseaPlankton)
