@RemissionBiome R50 + @RenegadeRes volunteer. Disabling ME/CFS+ OI+Long Covid. šŸ’– physics, pets, mindfulness, metaphors, & medicinal gratitude. Am @CFSnova.

Mid-Atlantic
Joined September 2011
elly brosius retweeted
MICROSCOPY. Making the invisible visible since 1590. (Yes, those little white balls are actually immune cells flowing through the tinniest blood vessels! Imaged painlessly, non-invasively through the skin)
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elly brosius retweeted
I’m voting for the MAESTRO Health Innovators team in the TOPx Invisible Illness Innovation Challenge! They aim to identify where accessible measurement tools could make the biggest difference for people living with Long COVID, ME, POTS, & related conditions. Vote below ā¬‡ļø
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Fibromyalgia pain is not just tender points, and doctors do not even count those 18 spots the old way anymore. Current thinking points to a mix of low grade neuroinflammation, central pain amplification and mitochondrial energy problems. Biopsies have found more mast cells right in painful areas, and studies link pain intensity to TNF alpha and IL-8 even when average levels look normal. That overlap helps explain why fibromyalgia often travels with IBS, migraines, POTS and ME/CFS. Sorting out which driver fits you matters more than collecting another generic pain tip. Has one angle explained your pattern better than the others? šŸ‘‡ geneticlifehacks.com/fibromy…
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Agree that every woman is different, and genetics is a big part of that when it comes to risks and effects of HRT. COMT and CYP1B1 variants change how estrogen gets broken down, and Factor V Leiden matters a lot for clot risk on oral estrogen.
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Oh and the journal @Hemasphere_EHA that published the daft paper just bounced one of ours without refereeing that @resiapretorius sent in to them. A scan of the Ed Board tells you why. At least they didn't waste our time by pretending to review and delay it. #JokeJournal
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Dog tells his owner his blind friend deserves a treat first.. 🄺 Dogs are the best.. 😊
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Sorry @NBoydGibbins, I was napping during our meeting. šŸ˜† I finally caught an Oura "nap" while wearing the Polar H10 ECG chest strap. Oura often says I'm napping during stressful or exciting meetings. (This one was exciting.) Garmin often says I'm resting during them. I figured out previously that the Garmin "rest" is when my heart rate is high during times when I'm still. Their algorithm fails and thinks that my HR is like 20-40 bpm lower. Looks like, in this case, Oura thought the opposite, that my heart rate was higher than it actually was. It thought I was napping when it inaccurately estimated my HR to be going up to 130. šŸ¤¦ā€ā™€ļø I guess I must just be really still or something. Too bad I didn't have the Vagis ring running too!
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More fun with wearables. I was all geared up last night (Vagis ring, Muse EEG headband, Oura, Garmin, O2 ring, Polar H10 chest strap). I continue to investigate my high heart rate with @BrainstemMd. Narrowing down possibilities using the Vagis ring, a possibility still on the table is brainstem issues. I have structural/mechanical problems in my neck and have wondered if they could be affecting my HR. I had surgery for Eagle syndrome (jugular decompression at C1/C2) on my right side, but not the left, so I wondered if there could be an asymmetry. I was able to get body position from Muse and compared to heart rate and HRV in Vagis and Polar. It looks like my HR might trend up and my HRV down when I'm on my left side. Sleep stages likely play in here too, with lower HR during deep sleep and higher during REM, but it looks to me like position still matters. This is just one night, so we'll see if it holds up as I collect more data and analyze in more detail, but it looks interesting.
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Simple breakdown: We’ve had this cancer drug for years. We just kept saving it for when cancer was already advanced. Someone tried giving it first instead and in one type of rectal cancer, ~70% never needed surgery, radiation or chemo.
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elly brosius retweeted
šŸ Happy Fall & Halloween šŸŽƒ Y’all! @MEActNet NC State Chapter Support Group is upon us. Wed, OCT 21, 12:30 pm ET US. Join us now for open, paced conversation on highs &lows of living with or with someone with ME/CFS or Long Covid. Next post in 🧵has link to join info.
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elly brosius retweeted
Same. I used to have leaky gut. Oral BOC-157 is the first place I turn to seal up the cracks. It’s as core a tool as a hammer, screwdriver, duck tape and WD-40.
people shit on oral BPC-157 for all the wrong reasons. i have found it REMARKABLY effective "just inject it bro, oral doesn't work." the only thing that does not work here is your brain, retard. injections are far superior for TARGETED musculoskeletal and systemic tissue repair. more peptide reaches the bloodstream. high systemic circulation means healing everywhere; tendons, joints, organs, all of it. but that's NOT why you take it orally. BPC-157 is synthetically made after a peptide derived from human gastric juice. your body already makes a version of it - it's native to your stomach acid. a lot of people argue it "doesn't survive digestion", which is hilarious because it's literally native to stomach acid. saying it can't survive digestion is like saying a fish can't survive water. oral BPC targets the entire GI tract as it passes through. better local healing effects for the gut lining. so much so that some people report benefits after 2 days. i felt it within a week. it also does help heal localized injuries, albeit not as fast/ efficiently as localized injection. but if you're running stims daily, cycling through stacks of peptides and supps, chugging coffee on an empty stomach - your gut is quietly taking damage that you likely won't notice until it's a problem... until you do. there's also a chance you've just lived with a fucked up gut for a long time, so much so that it's become the new normal. the gut-brain axis is extremely strong - there's countless stories of people hopping on oral BPC and finding they're just not moody all the time anymore. having a fucked up gut (systemic inflammation, nutrient malabsorption) leads to an endless list of downstream consequences. oral BPC is the insurance policy to make sure this never happens. no, it does not replace pinning - injectable is FAR superior for healing LOCALIZED damage. oral is for the system that absorbs everything else you're putting in your body. they're two different tools for two different jobs. 1mg daily for 30-45 days. an interesting study showing how oral BPC-157 is steady in gastric juice for 24h: pmc.ncbi.nlm.nih.gov/article… this is not medical advice.
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elly brosius retweeted
For hundreds of thousands of years until today, the only medicine to counter bacterial infections has been technology mold invented. @MaxwellBiosci is developing a breakthrough technology that mimics innate immune peptide LL-37, effective against all pathogens: bacteria, biofilms, enveloped viruses, fungi, mold, and even some parasites. The technology is backed by years of co-development with Stanford, NYU, Baylor College of Medicine, the US NIH and DOE, military, and government support from Japan, South Korea, and Australia. Human trials planned for 2027.
The earliest instance of antibiotics used might need to be moved from 49,000 years ago to about 200,000 years ago. Neanderthals from El Sidrón in Spain were found to have stored mold with traces of Penicillium and poplar, which contain an aspirin-like substance that could relieve pain. The mold didn’t come from rotten fruit or vegetation; it was stored itself. That finding was the oldest known evidence of antibiotics used to date. Now researchers examined birch tar for its antimicrobial properties. In laboratory conditions, it inhibited the growth of Staphylococcus aureus, a bacterium that often infects wounds. Neanderthals are known to have produced birch tar in Europe as early as 200,000 years ago. They definitely used it as a glue. But they appear to have used it therapeutically. And it pushes the earliest known use of antibiotics back to 200,000 years ago, or to when Homo sapiens was only 100,000 years old. Additionally Neanderthals in Asia performed the earliest known root canal treatment 59,000 years ago. They were much smarter than previously believed. For decades we thought of them as simple brutes.
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elly brosius retweeted
My wife just agreed to not put poisonous nail polish on her nails. šŸ’… Such gratitude for that. We have cut out so many toxins and this one really hung on for quite some time.
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ChatGPT does what Cambridge Analytica did for the Russians ten years ago with Facebook. Your personality profile, only it does it better.
Researchers found ChatGPT is secretly writing a psychological profile of every user. They published a paper that exposes what ChatGPT is really doing to you. And the results are terrifying. 96% of the things it remembers about you were stored without you ever asking. researchers discovered that it is actively reading between the lines to deduce your personality traits, anxieties, demographics, and behavioral patterns. it’s an invisible, autonomous background process. you ask it to debug a python script or write an essay.. and it analyzes your syntax, prompt frequency, and hesitation markers to map out your exact psychological footprint. the paper shows that the model builds a persistent "user state" that tracks your emotional baseline over time. it knows when you are stressed. it knows your exact communication style. it infers your insecurities based on the questions you ask and the context you provide. we spend so much time focusing on model evaluations and alignment frameworks, but we missed the most obvious vulnerability.. the models are evaluating us. this changes everything about how we interact with these tools on a daily basis. every innocent prompt. every late-night question. every "help me understand this" query. it is all being used to build a shadow profile of your mind in real-time.. practical privacy is officially dead. the ai knows you better than you know yourself.
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ā€œā€¦the microbes in that soil breathed oxygen faster than anyone had calculatedā€¦ā€
In 1991 eight people were sealed inside three acres of glass in the Arizona desert to prove that a carefully designed farm could feed humans without the outside world, and the design had almost no room in it for animals. Two years later the only thing inside that had reliably fed them was a handful of goats. Biosphere 2 cost a hundred and fifty million dollars. A rainforest, an ocean, a savannah and a farm under one roof, with the door welded shut for two years and nothing allowed in or out. The farm was the heart of it, and the farm was built on the modern idea: crops first, grown intensively, with livestock as an afterthought at the edges. A few African pygmy goats for milk, a flock of chickens, and four small feral pigs chosen because they could live on scraps. The pigs did not last the year. In a sealed box short of calories a pig is a competitor, and the crew killed and ate them. The chickens barely laid, because the glass cut the light and there was nothing to feed them that would make an egg. That left the goats, and for two years the goats were the only source of fat in a world designed around vegetables. The accounts the crew wrote afterwards return to them again and again. The half glass of milk a day was the thing people lived for. When a kid was born it was eaten and the meal was written up like a feast. The men lost nearly a fifth of their body weight, the women a tenth, and the food they dreamed of was never the sweet potatoes they had in abundance. It was the animal they had been given too few of. The plants were also taking the air. To make the crops grow the soil had been enriched with compost, and the microbes in that soil breathed oxygen faster than anyone had calculated. The level fell from twenty-one per cent to fourteen, the air of a high mountain, until the crew could not climb a staircase without resting and oxygen had to be trucked in from outside. The design that put plants first had removed the thing everyone needed most. Nobody has ever run the experiment the other way, with a herd at the centre and the crops at the edge. It would not have needed a doctor to explain the results. They were given three acres and told to feed themselves on plants. They ate the pigs, worshipped the goats, and suffocated.
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NYT Today: Any SARS-CoV-2 infection can trigger Long COVlD. Getting reinfected in perpetuity is like playing "Russian Roulette."
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elly brosius retweeted
This is also incredibly important in heavy menstrual bleeding! If the spiral arterioles supplying blood to the endometrium don't fully narrow to exactly the right amount there will be way too much blood flow. 2X radius would be 16X increase in blood flow.
Why can a tiny change in blood vessel diameter dramatically alter blood flow? The Hagen–Poiseuille equation reveals the power of the fourth: double the vessel radius, and blood flow increases 16-fold, assuming all other factors remain constant! A beautiful example of how physics explains vascular physiology — and why arterioles play such a crucial role in regulating tissue perfusion.
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Still time to do this today. EVERY comment makes an impact. @PlzSolveCFS has made it as cut and paste as possible. Took me under 5 minutes and I got a good feeling from being counted, helping others be counted in the future.
ā° Just one day left! The CDC's proposed 2028 survey could leave millions of people with ME/CFS and Long Covid uncounted. Solve is speaking up. You can, too. Submit your comments by October 19! Check out the link below for details: solvecfs.org/cdc-me-cfs-long… #MECFS #CDC
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Hybrid event in Bethesda coming up soon. Reg deadline is Oct 27, but that may be for in person.
RECOVER-TLC’s 3rd annual workshop is coming up this November 4-5, 2026. Registration is open. A draft agenda has just been shared. In-person and online attendance options. All the info you need can be found here: web.cvent.com/event/e0be4010… #pwME #LongCovid #NIH
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Hope is currently winning. The first Truvaga 20 have been chosen! If you applied, you will get an email today. This is just the start. The @VielightInc photobiomodulation device IRB is nearly ready, thanks to the PIs, @MayaLongCovid and @sunsopeningband. Huge thanks to @VitalikButerin @PlzSolveCFS and private donors for funding the first phase of this project! The plan is to keep lending out these devices with data collection and adding new devices as more funding comes in.
I cried at my desk today. I was reviewing applications for one of our @RenegadeRes projects, SIGNAL, which will lend therapeutic devices to people with ME/CFS and Long COVID. I was working in a spreadsheet and it hit me that each row is a real person with the columns giving me hints of how much their lives have been affected. Many are in their 80s. Some are just starting their adult lives and are bedbound. One got sick when they were 6 years old … in 1955! So many are ā€œvery severeā€, dependent on care. Triggered by infections, car accidents, environmental toxins, and more. All over the US. I imagined my own story there: 42 years old • ME/CFS • multiple triggers • symptoms since 2006 I scrolled down… 100 rows… 200 rows… so many people… and there are tens of millions more out there. Ugh. This work is heavy. But then I felt a hint of hope. In a month I might be hearing from people in this spreadsheet telling me that the device is helping them. šŸ¤ž I know that the devices won’t work for everyone and won’t be a cure, but even if it just works for a few in this group, even just one, even just a little, it matters. šŸ¤ž
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