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DEMIR Lab

@PancNeuropathy

Scientific group @tu_muenchen Dept. of surgery | Working on the influence and interaction of #nerves in #Pancreaticcancer and #chronicpancreatitis

 Munich, Germany
chir.med.tum.de/forschung/pankreaszentrum
Joined January 2023
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  • Followers135
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Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)Photo by DEMIR Lab (@PancNeuropathy)
Cancers thrive on neuronal input, especially on glutamate delivered via neuron-cancer pseudo-synapses! With this study, we show the presence of such pseudo-synaptic sites in human pancreatic cancer and that targeting this axis disrupts tumor progression. dlvr.it/TNJdXB
Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-sy...

Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-sy...

Ren et al. demonstrate pseudo-synaptic connections between sensory neurons and pancreatic ductal adenocarcinoma (PDAC) cells. These pseudo-synapses exhibit enrichment of NMDA receptor subunit...

cell.com
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Online Now: Functional pseudo-synapses: A new nexus in extracranial cancer dlvr.it/TNsk95
Image from Cancer Cell (@Cancer_Cell)
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Our postdoc, Dr. Carmen Mota Reyes, is presenting her multiomic data as a poster spotlight at the #EACR #CancerNeuroscience Conference in Bilbao, Spain! 👏👏
Image from DEMIR Lab (@PancNeuropathy)
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🚨 Double Award Alert! 🚨 Congratulations to Dr. Mara Goetz for receiving the Walter Brendel Prize and to Dr. Rüdiger Göß for winning the Best Poster Prize at #VBC2025!! 👏👏👏👏👏
Image from DEMIR Lab (@PancNeuropathy)
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Neural invasion is a hallmark of pancreatic cancer, but how does it occur? Our recent study suggests that TGF-β1 could be a key player👇 sciencedirect.com/science/ar…
Image from DEMIR Lab (@PancNeuropathy)
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We are delighted to announce that our lab member Dr. Carmen Mota Reyes has won the first-ever EPC Female Scientist Award at the European Pancreatic Club 2025!! #EPC2025
Image from DEMIR Lab (@PancNeuropathy)
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Online Now: Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses dlvr.it/TNJdXB
Image from Cancer Cell (@Cancer_Cell)
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Pinpointing neurons that hinder cancer treatment nature.com/articles/d41586-0…
Pinpointing neurons that hinder cancer treatment

Pinpointing neurons that hinder cancer treatment

Nature - Method to identify neurons associated with pancreatic cancer.

nature.com
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We are delighted to announce that our doctoral student Kaan Cifcibasi has won the Walter Brendel Prize at #VBC2024!!
Image from DEMIR Lab (@PancNeuropathy)
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Our lab members Alper Dogruoz, Dr. Okan Safak, and Kaan Cifcibasi presenting our latest studies at #VBC2024
Image from DEMIR Lab (@PancNeuropathy)
Image from DEMIR Lab (@PancNeuropathy)
Image from DEMIR Lab (@PancNeuropathy)
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We are thrilled to announce that our doctoral student Kaan Cifcibasi won the Best Cancer Neuroscience Poster Award at @CanNeuroSociety hosted by @MDAndersonNews!! #CancerNeuroscience
Image from DEMIR Lab (@PancNeuropathy)
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Our lab student Kaan Cifcibasi presenting his highly interesting #spatialtranscriptomic data in PDAC @German_PancClub ! Meet us at the Congress! #pancreaticcancer #cancer #pankreasclub #bonn #demirlab
Image from DEMIR Lab (@PancNeuropathy)
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📣 Keystone Symposia 2025 📣 Join us for this great event! keystonesymposia.org/confere…   Scientific Organizers: Brian M. Davis, @michelle_monje and Ihsan Ekin Demir Date & Location: January 18-21, 2025 |Fairmont Banff Springs, Canada #KSNeuroCancer25
Image from DEMIR Lab (@PancNeuropathy)
Image from DEMIR Lab (@PancNeuropathy)
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Publication alert 🚨 “Lymph node examination and survival in resected pancreatic ductal adenocarcinoma: retrospective study” pubmed.ncbi.nlm.nih.gov/3827… #cancer #research #pancreaticcancer #lymphnode #munich #surgery @BjsOpen
Image from DEMIR Lab (@PancNeuropathy)
Image from DEMIR Lab (@PancNeuropathy)
Image from DEMIR Lab (@PancNeuropathy)
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The 2024 Cancer Neuroscience symposium at @MDAndersonNews (co-led by @moranamit2) has a series of podcasts featuring research to be presented at the meeting. This week’s guest is Prof Ihsan Ekin Demir (very apt handle @PancNeuropathy) @TU_Muenchen m.youtube.com/watch?v=xVbkjH…
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Dr. Demir is one of the foremost experts on neural influences in cancer, with a particular focus on #PancreaticCancer. cell.com/cancer-cell/fulltex…
Clinically Actionable Strategies for Studying Neural Influences in Cancer

Clinically Actionable Strategies for Studying Neural Influences in Cancer

Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects,...

cell.com
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Young investigator grant from the International Association of Pancreatology and foundation of @apapancreas for our lab member Dr. Carmen Mota Reyes! What a great success! 👍🏼🤩 #younginvestigatorgrant #research #cancer #pancreaticcancer #munich @TU_Muenchen
Image from DEMIR Lab (@PancNeuropathy)
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Relationship of nerves and cancer cells in IHC Double Staining with CK7 and S100 in #pancreaticcancer #cancer #research #munich #pancneuropathy #lab #ihc
Image from DEMIR Lab (@PancNeuropathy)
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Is #arterialresection a feasible and reasonable surgical intervention in #pancreaticcancer patients? Check our latest retrospective study on this highly interesting and relevant topic! journals.lww.com/aosopen/ful… #pancreaticcancer #cancer #surgery #munich
Image from DEMIR Lab (@PancNeuropathy)
Image from DEMIR Lab (@PancNeuropathy)
Image from DEMIR Lab (@PancNeuropathy)
Image from DEMIR Lab (@PancNeuropathy)
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Nicht verpassen: Noch bis 1. Okt. 2023 Abstracts für #DCK2024 einreichen! Die Besonderheit beim Chirurgenkongress sind interdisziplinäre Sitzungen von chirurgischen und aller Partnerfächer! Gestalten Sie das wissenschaftliche Programm mit👉🏻 dck2024.de/abstracts/
Image from DEUTSCHE GESELLSCHAFT FÜR CHIRURGIE e.V. (DGCH) (@DCKongress)
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