Dedicated to the development of creative methods for the synthesis of complex molecules
Amsterdam, The Netherlands
Joined March 2021
- Tweets183
- Following163
- Followers634
- Likes591
RuijterLab retweeted
Woke up at 5:45 this morning😴, but it was totally worth it!😊 Had a blast sharing some sugar-sweet chemistry at the @HRSMC1 symposium and loved all the insightful talks!🍬🍫 Great to see this community together!🎉
RuijterLab retweeted
Now as early view @angew_chem: Structure-Based Design of Bicyclic Helical Peptides That Target the Oncogene β-Catenin doi.org/10.1002/anie.2024117…
Big congrats to first author @YesteAlejandro
& thanks to our great collaborators @Al_rebreG @maric_hans @SchulteClemens #peptidomimetics
RuijterLab retweeted
Out now @angew_chem: Structure-Based Design of Bicyclic Helical Peptides That Target the Oncogene β-Catenin doi.org/10.1002/anie.2024117…
Big congratulations to first author @YesteAlejandro and thanks to the great collaboration partners @Al_rebreG @maric_hans @SchulteClemens
RuijterLab retweeted
@PascalVermeeren wins KNCV-CTC Thesis Award🏆! Well done Pascal! 🎉 @KNCVchemie @VU_TheoCheM @VU_Science.
The final version is now out in @ChemEurJ Early View!
Read it here:
chemistry-europe.onlinelibra…
Do you think the Ugi multicomponent reaction:
- is only useful for boring small molecules?
- does not work with hindered ketimines?
- has poor diastereoselectivity?
Then read our latest work (Open Access!), just out as Acceped Article in @ChemEurJ: doi.org/10.1002/chem.2024004…
RuijterLab retweeted
Are you coming to the 2024 Dutch Peptide Symposium, May 31 at VU Amsterdam O2 auditorium? We have some exciting invited speakers confirmed, and now we need you! Registration is open until 20 May, abstracts until 1 May, all on dutchpeptidesymposium.com/
Our recent paper in @ChemEurJ on iron-catalyzed carbene transfer to isocyanides attracted significant attention from the chemistry community and is now a #TopDownloadedArticle!
Read it yourself (Open Access!): doi.org/10.1002/chem.2022030…
RuijterLab retweeted
Now online: Transcription factor-targeting stapled peptides @ChemBioChem
We've captured 2 peptide confirmations with crystal structures & used MD simulations to understand the dynamics doi.org/10.1002/cbic.2024000…
Congrats @Canan_Durukann @ioana_ilie_UvA @jocelyne_vreede @VU_Science
Do you think the Ugi multicomponent reaction:
- is only useful for boring small molecules?
- does not work with hindered ketimines?
- has poor diastereoselectivity?
Then read our latest work (Open Access!), just out as Acceped Article in @ChemEurJ: doi.org/10.1002/chem.2024004…
We use an intermediate from our recent total synthesis of monoterpene indole alkaloids as the imine input in a three-component Ugi reaction to gain rapid access to diverse, highly functionalized 'synthetic alkaloids'. @brendan_horst @THansenChem
Petasis three-component reaction without the classic restriction on the aldehyde input: great work! The scope of accessible branched tertiary amines is amazing!
Now you can Petasis (virtually) any borons! Super simple and powerful method to prep fully-sp3 complex amines is now on @ChemRxiv as our collaborative work with @QinLab. Congrats on everyone's accomplishment! @JetTsien @SijieChen17 @rohanmerchant1
go.shr.lc/48Usx0t
RuijterLab retweeted
Very proud of this work! 🔥
In 2021, our work on understanding H2 activation by metallylenes appeared in @ChemicalScience (doi.org/10.1039/D0SC05987K). Now we close the cycle and report how these metallylenes can potentially catalyze hydrogenation reactions in @EurJOC!⬇️
Less than a week left until the Early Bird deadline, so register now for the 2024 Dutch Symposium on Organic Chemistry!
Also, note a small update in our speaker line-up (see flyer).
Register here: soc.kncv.nl/reg-2024
More info: soc.kncv.nl/dsoc-2024
RuijterLab retweeted
What a team effort it was, and the end result just blew our minds. If you want to know the story behind #RoboChem, check our blog article: noelresearchgroup.com/2024/0…
I promise you there are some funny passages, drama and a happy ending with its publication today in @ScienceMagazine
We're absolutely thrilled that our robotic platform, #RoboChem, has been published in @ScienceMagazine!
🔗science.org/doi/10.1126/scie…
#RoboChem can carry out your substrate scope and provide tailored reaction conditions for every single entry. 🤖
#FlowChemistry #photocatalysis
RuijterLab retweeted
Don't miss F. Matthias Bickelhaupt's et al.'s recent article - it's one of this week's #ChemSciCovers
Nature and strength of group-14 A–A′ bonds
🔗 DOIhttps://doi.org/10.1039/D3SC06215E
@Daniela_R_Silva @EvaBlokker @TrevorAHamlin @fmbickelhaupt @VU_TheoCheM
Join us in Lunteren at the biannual Dutch Symposium on Organic Chemistry - April 4-5, 2024!
@soc_kncv invites you to two days of exciting developments in organic chemistry!
Register here: soc.kncv.nl/reg-2024
More info: soc.kncv.nl/dsoc-2024
RuijterLab retweeted
We're absolutely thrilled that our robotic platform, #RoboChem, has been published in @ScienceMagazine!
🔗science.org/doi/10.1126/scie…
#RoboChem can carry out your substrate scope and provide tailored reaction conditions for every single entry. 🤖
#FlowChemistry #photocatalysis
RuijterLab retweeted
One way or another!🍎↔️🍐 We explain in our new @JOC_OL how minimal changes in the donor impact the formation of different reactive intermediates and stereoselectivity!💥 Great Leiden-A'dam-Nijmegen team work!🤜🤛 @WA_Remmerswaal @HiddeElferink
🗞️▶️ doi.org/10.1021/acs.joc.3c02…
RuijterLab retweeted
Our #OpenAccess paper on the Blueshift in Trifurcated Hydrogen Bonds was featured on the cover of @ChemPhysChem! 🔥
Cover: doi.org/10.1002/cphc.2023009…
Paper: doi.org/10.1002/cphc.2023009…
@LucasAzdS Storm Shiri @CeliaFGuerra @fmbickelhaupt @VUamsterdam
