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Sara Elizabeth Siegler (SES) is a cell-based gene therapy focused woman owned small business. Disclaimer: therapies are investigational unless otherwise noted.

Bedford, OH
Joined November 2020
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The CAR T CELLS - Beyond the Basics presentation is available at the following URL: youtu.be/IVBXDTwd8qY Please check the description box for the link to the slides as a PDF.
I’m having trouble reconciling an IND with a variable number of neoantigens (being a single IND) versus a manufacturing change that can result in a new IND. I understand that the modalities differ. Who is able to provide clarity here? @FDACBER
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What do you think of the draft guidance on CMC changes from @US_FDA @FDACBER? #cellbasedgenetherapies #CARTcells #TCRTcells #CARTCR #CMC #processdevelopment
There’s one thing I forgot to mention, @bllphd. See the next tweet.
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Pre-application: submitted!
Our CEO will be headed to DC to lobby — hopefully come spring — for more funding to develop cancer therapies for privately owned small businesses that aim to avoid a merger or acquisition.
I have started to work on the summary sheets I will be providing to our elected officials when I go to DC. Advice and feedback are both welcome. Keep in mind that this is just a very rough, first draft for one of many legislative priorities. @RepDianaDeGette @RepFredUpton
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We would like to share a message from our CEO on this #WorldCancerDay:
It’s #WorldCancerDay, and if you care, please be sure to let @theNCI know that its funding needs to be completely reprioritized. Tell them to stop aiding and abetting academia as the cost of college and healthcare is destroying the country for future generations. @RepFredUpton
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I’m thinking about trying out some new ideas this year to bring in some extra income since I am still bootstrapping @SES_HQ. What type of content would be valuable enough to you to warrant payment?
0%Online teaching
50%Consulting
50%Other - comment below
2 votes • Final results
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SES would like to wish you a safe new year! For those who are interested in our work, we would love to know which programs or projects you would like to see prioritized in 2022 in terms of @NIHFunding applications; our CEO is not able to bootstrap the next steps by herself.
0%NAPSA program
100%GAGE-1 program
0%Other
1 votes • Final results
Our CEO continues to train. Like Oscar Wilde said, you can never be overeducated.
Three tests down. Three tests to go. #training
There’s a new healthcare company in Menlo Park CA that is using the name of my company’s facility (“The Factory”) as its name, although the “The” is missing from their website. Please don’t get confused. This CA entity has nothing to do with @SES_HQ.
NAPSA P01 application: ☑️
“Be the change you want to see the world.” - K. Rae teapawt.net/alvinfoo/status/141164…
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Submitted today.
It’s impossible to beat someone who refuses to give up.
How much do you know about the trailblazing scientist Barbara McClintock? McClintock's pioneering research was rejected by the scientific community but she didn't give up. Watch our video to learn more about this remarkable laureate who was born today 119 years ago. #NobelPrize
The path to developing a new treatment modality is a long and arduous one. It took us many years to get there for the blood cancers. At SES, we believe that we will get there for solid tumors too. RT and like if you agree. #CARTcells
Happy pride month to all of the lovely members of the LGBTQ+ community! Please know that you are welcome at SES. Come as you are. 🌈❤️🧡💛💚💙💜🌈
“Two roads diverged in a wood, and I — I took the one less traveled by, And that has made all the difference.”