@Seb_Amos

Lecturer and Anatomy Discipline Lead @ UWA Medical School | Bioimage Informatics & Cancer Cell Mechanobiology

 Perth, Western Australia
Joined October 2018
  • Tweets26
  • Following252
  • Followers143
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Sebastian Amos retweeted
Yu Suk CHOI@YuSukChoi20 Sep 2023
How do cancer spheroids mechanosense in 3D? Plz read @Danielle_Vahala 's first first-author research paper! @Seb_Amos @Bramzelll @Khoonono @UWAresearch @ASBTE1 @AuSMBSoc @MatrixBioANZ @PerkinsComms @Sydney_Uni #mechanobiology onlinelibrary.wiley.com/doi/…

3D Volumetric Mechanosensation of MCF7 Breast Cancer Spheroids in a Linear Stiffness Gradient GelAGE

There is a constant need for biomaterials that offer a high degree of tuneability to greater recapitulate the variable tissue properties noted in diseased tissues, such as breast cancer. Using a...

advanced.onlinelibrary.wiley.com
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I was delighted to present my #BioImageAnalysis work at #ACMM27 earlier this month. Extremely humbled to receive the John Farrant Prize for the best student talk in Biological/Medical Sciences. Very excited to release this project soon! #Microscopy #ImageJ @YuSukChoi @UWAresearch
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Last week, I had a fantastic time discussing all things mechanobiology at #ISMB2022 in Sydney. Such a great experience to listen to and share our work with leaders in the field! @YuSukChoi @SamuelJMaher @Danielle_Vahala @IanLChin @uwaresarch @uwashs @asbte @yonghwee_joe @AuSMBSoc
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@UWAresearch @UWAhumanscience
Sebastian Amos retweeted
Yu Suk CHOI@YuSukChoi5 Nov 2022
The whole Western Australia (Choi lab) taking off to Sydney for #ISMB2022 Samuel Maher @Danielle_Vahala Joe Tan @Seb_Amos and @IanLChin (already in Syd) check out rapid fire and posters! @AuSMBSoc
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Sebastian Amos retweeted
Yu Suk CHOI@YuSukChoi14 Oct 2022
Trilogy completed by @IanLChin and @Seb_Amos on cardiac mechanobiology! 1 - H9C2/NRCM in 2D doi.org/10.1039/D1BM01061A 2 - H9C2 single/spheroid in 3D doi.org/10.1016/j.mtbio.2022… 3 - NRCM spheroid in 3D doi.org/10.1002/jbm.a.37456 @LiviaHool @UWAresearch @ASBTE1 @AuSMBSoc @MatrixBioANZ
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Sebastian Amos retweeted
Yu Suk CHOI@YuSukChoi8 Sep 2022
3D cardiac mechanosensation as an individual vs. spheroidal culture. Congrats to authors @IanLChin @Seb_Amos @LiviaHool @UWAresearch @ASBTE1 @AuSMBSoc @VictorChangInst @heartfoundation
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Sebastian Amos retweeted
Yu Suk CHOI@YuSukChoi22 Aug 2022
Cardiomyocyte volume mediates mechanosensation in 3D by @IanLChin expanding our previous understanding of cardiomyocyte mechanosensation in 2D (pubs.rsc.org/en/content/arti…). doi.org/10.1016/j.mtbio.2022… @ASBTE1 @MatrixBioANZ @AuSMBSoc @UWAhumanscience @UWAresearch @OzCvA @LiviaHool

Interrogating cardiac muscle cell mechanobiology on stiffness gradient hydrogels†

Extracellular matrix (ECM) remodeling is a major facet of cardiac development and disease, yet our understanding of cardiomyocyte mechanotransduction remai

pubs.rsc.org
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Sebastian Amos retweeted
Yu Suk CHOI@YuSukChoi13 Aug 2022
Showcasing the hard work of @Seb_Amos, PhD student in improving 3D imaging and volumetric analysis (photo in the right obviously😆) Cells look so different in 3D vs on 2D (spheroid green vs. individual orange) @UWAresearch @UWAhumanscience @AuSMBSoc @ASBTE1 @MatrixBioANZ
ANZSCDB@ANZSCDB11 Aug 2022
Welcome to our new @ANZSCDB state rep for Western Australia! Dr @YuSukChoi aims to develop biomimetic hydrogels to study mechanical interaction between cells and their microenvironment. Image credit @Seb_Amos
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My research focuses on the mechanical challenges that cancer cells must navigate to spread successfully, a process known as metastasis. I study changes to cancer cell adhesion and the mechanical conditioning that might enhance and protect them on their deadly journey.
BioZoneUWA@BioZoneUWA18 Oct 2021
Hydrogels are used to mimic the mechanical and chemical properties of tissues which allow for cells to be studied in more representative and translatable environments. #biozone #uwa @UWAresearch
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To study the initial steps of the metastatic cascade, I use hydrogels to mimic normal and cancerous microenvironments in 3D. This allows me to investigate how tumour growth, escape and local invasion are mechanically linked.
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Whether it’s in the fight against cancer or progress towards regenerative medicine, in the case of my colleague, Sam, hydrogels improve the translatability of our research… and let us capture stunning 3D datasets!
Sebastian Amos retweeted
BioZoneUWA@BioZoneUWA6 Sep 2021
BioZone PhD candidates @Seb_Amos, @Danielle_Vahala, Sam and Eric had a fantastic time participating in the @UWAPSA Research Week Sundowner! They spoke about the BioZone program and all things research and innovation with students, staff and industry professionals. #biozone
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Sebastian Amos retweeted
BioZoneUWA@BioZoneUWA23 Aug 2021
We're back! Meet the BioZone cohort! Here at BioZone, we seek innovative solutions that address the increasing complexity of local and global challenges as well as 'wicked problems'. These problems require transformative change in the way we learn, think and interact.
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Sebastian Amos retweeted
Yu Suk CHOI@YuSukChoi16 Feb 2021
Seb (PhD student in the lab)'s review paper on 'Cancer Microenvironment: Mechanical Challenges of the Metastatic Cascade' frontiersin.org/article/10.3… @UWAresearch @MatrixBioANZ @ASBTE1
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Congratulations CCREM honours student @amos_seb winner of the 2018 Joy and Malcolm Sparrow Physiology Excellence in Honours Prize AND the 2018 Robert Collin Honours Prize in Anatomy, Physiology and Human Biology. Well deserved! @erika_bosio @UWAresearch @ScienceUWA @PerkinsComms
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Sebastian Amos retweeted
Yu Suk CHOI@YuSukChoi16 Dec 2018
Just saying thx to 3 honours students, Jeet (left), Seb (right) and Quinn (away) who put up with me last 8 months #UWA #mechanobiology @amos_seb @ScienceUWA
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