Investor, entrepreneur, lover of strenuous activities. Dad of 3, husband of 1. Obsessed with longevity. Cofounder of Overview. Writing Healthspan Dispatch.

Denver
Joined July 2013
1/ "We only buy API from FDA-registered facilities." Most peptide clinics and pharmacies say some version of this. It sounds reassuring, but it's a legal minimum, not a quality signal. Here's what it does and doesn't tell you:
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Heineken is coaching UK pubs to push half-pints and small plates because of GLP-1s. The US data shows why: in EY-Parthenon's new survey, 45% of users cut back on alcohol and 40% quit. And 94% run the household grocery list. One prescription changes the whole cart.
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Wall Street just priced MAHA. Calley Means resigned Thursday. General Mills, Kraft Heinz, Campbell's and Conagra closed up 6.7% to 8.7% while the S&P fell 1.2%. The bet isn't on cereal. It's on a federal UPF definition stuck at OMB since August.
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The 2nd order GLP-1 effects continue!Ozempic face is a business now. BCG projects clinical treatments for it growing from about $700M to $2B in five years. Galderma, L'Oréal and Natura are testing products on GLP-1 users. Dermatologists say creams can't reach the lost fat layer. The money goes to injectors.
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Blood panels went commodity. Imaging is next: Fitnescity opened DEXA, bone density and CT calcium scoring at 1,000+ sites to health platforms through one API. Superpower is among the first 10. When anyone can sell the scan, the moat is what happens after the result.
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Hims and Ro already sell cheap generic oral minoxidil for hair loss. Veradermics just posted a second positive registration trial for an extended-release version, and its pitch to telehealth is blunt: generics are a race to the bottom on price. A branded pill is a margin play.
Veradermics experimental hair loss pill, an extended release form of minoxidil, boosted hair growth in a Phase 3 trial of 536 men, with results appearing within two months. After 6 months, the twice daily group gained 36.4 hairs/cm² versus 6.6 with placebo, with no treatment related serious adverse events reported.
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Michael Silverman retweeted
Veradermics experimental hair loss pill, an extended release form of minoxidil, boosted hair growth in a Phase 3 trial of 536 men, with results appearing within two months. After 6 months, the twice daily group gained 36.4 hairs/cm² versus 6.6 with placebo, with no treatment related serious adverse events reported.
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Galleri's 50-cancer blood test lists at $949, with $250 off online orders through Dec 31. Makes you wonder what margin private-pay providers get. Most insurance won't cover it. FDA advisers split 6-4 on effectiveness, and Medicare coverage couldn't start until 2028. Until then it's a cash market, and a boon for clinics that own the follow-up and re-testing.
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A Nasdaq-listed pharmacy company just named its target customer: people who've been buying peptides on the grey market. The hard part isn't price. The most experienced grey-market buyers already send vials to independent labs. A license and a prescription won't win them. Publishing lot-specific testing on the finished vial, better than what they can get on their own, might.
The Grey-Market Peptide Customer Is Now a Target for US Pharmacies The FDA hasn’t finalised its proposed peptide-compounding policy, but one US healthcare company is already planning to target customers who've been buying peptides through the grey market. On 16 October, DataMeds AI (NASDAQ: MEDS) announced plans to expand its Corexa Health operations into the emerging market for pharmacy-compounded peptides. Buried in the announcement was a particularly interesting statement: “DataMEDS intends to initially focus its peptides marketing towards patients who have historically obtained peptides through the grey market.” That’s a fairly direct acknowledgement of a customer base that pharmaceutical and healthcare businesses have often preferred to distance themselves from. Corexa Pharmacy is already an established Section 503A compounding pharmacy. The company intends to begin dispensing eligible peptides if the FDA’s proposed interim access policy takes effect. It also has much of the infrastructure in place. Its distribution division operates a 40,000-square-foot warehouse in Florida, reports licensing across all 50 US states and has access to a network of more than 6,500 independent pharmacies. Its technology division plans to connect doctors, patients and pharmacies through the Health Lives Here app, handling prescription referrals and helping patients access compounded treatments. DataMeds expects the market to be predominantly cash-pay, which it sees as an advantage because it reduces reliance on insurance reimbursement. The company is already reviewing potential peptide API suppliers and expects to arrange sourcing contracts in the coming weeks. The FDA policy remains a proposal, with the final list of eligible peptides and conditions for compounding still to be confirmed. But will grey-market customers actually move? This is where DataMeds’ strategy becomes interesting. Many established peptide buyers use the grey market precisely because of price and access. Some purchase directly from Chinese suppliers, arrange independent laboratory testing and still pay considerably less than they would through a typical US pharmacy. DataMeds wants to introduce prescriptions, licensed compounding, US distribution and a telehealth platform. All of those services come with costs. There will undoubtedly be customers willing to pay more for regulated sourcing, medical supervision and convenience. But converting price-conscious grey-market buyers into cash-paying pharmacy customers could prove difficult. The company has identified an existing customer base, but identifying those customers and persuading them to change how they buy are two very different things. The irony is that DataMeds sees grey-market buyers as a commercial opportunity, while the prices that attracted many of those buyers to the grey market may be exactly what keeps them there. The FDA is still working out the rules. DataMeds is already working out how to get the customers. Source: DataMeds AI / Corexa Health announcement, 16 October 2026.
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Children of centenarians lived about three years longer and had a 42% lower risk of dying at any given age. The edge was mostly cardiovascular, not cancer. Longevity clinics sell $5K genome panels, but one of the strongest predictors is free and takes 30 seconds to collect: how long your parents lived, and what killed them. The clinic that turns family history into a real risk score and a training plan will beat the one selling another generic panel.
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FDA inspectors found black mold and bugs at a Chinese plant making GLP-1 ingredients for compounding. Worse, another plant was stamping its own name on ingredients made somewhere else. That's the problem in one story: the pharmacy's paperwork can point to the wrong factory. A COA from the seller isn't proof of where the API came from. If you're on a compounded GLP-1 or peptide, ask who actually manufactured the API and whether the finished vial was tested.
🚨 FDA inspection reports obtained by Bloomberg show black mold, bugs and staff hiding documents at Chengdu Shengnuo, a Chinese maker of semaglutide and tirzepatide ingredients for compounding. A second plant, Nanjing Chengong, put its own stamp on ingredients made at other factories without checking their test results. Both are now on FDA import alert.
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I traced how this supply chain works, from API to vial: healthspandispatch.substack.…
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