Statistical geneticist. Professor of Human Genetics and Biostatistics at the University of Pittsburgh. Assiduously meticulous. Mastodon: @StatGenDan@fediscience
Pittsburgh, PA
Joined July 2016
- Tweets2.5K
- Following1.3K
- Followers1.5K
- Likes5K
Daniel E. Weeks retweeted
Please RT!
🧬Postdoc Opportunity in Statistical/Computational Genetics!🧬
Join our team in Human Genetics @PittPubHealth! Focus: Genetic etiology of cardiometabolic disease in Samoans & Pacific Islanders. Collaboration with @CharlestonCWKC
tinyurl.com/pitthugen
#Postdoc #Academicjobs
Daniel E. Weeks retweeted
🧬Postdoc Opportunity in Statistical/Computational Genetics!🧬
Join our team in Human Genetics @PittPubHealth! Focus: Genetic etiology of cardiometabolic disease in Samoans & Pacific Islanders. Collaboration with @CharlestonCWKC
tinyurl.com/pitthugen
#Postdoc #Academicjobs
Daniel E. Weeks retweeted
Feeling frustrated when trying to put together your dbGaP data submission? @StatGenDan and I are excited to announce our new R package, #dbGaPCheckup, which we designed to help YOU with this complex process! 🧵(1/n) #Rstats #Genetics #dbGaP #DataQC #DataSharing #OpenScience
Daniel E. Weeks retweeted
We are excited to share our new work @Nature, led by @Lenka_Dohnal, uncovering a gut-brain pathway that regulates the motivation for #exercise. (1/7)
nature.com/articles/s41586-0…
Daniel E. Weeks retweeted
We released a commentary on Ioannidis et al (2021) as a preprint. To date the settling of Polynesian islands, they inferred split times using IBD segments shared between modern genomes. We show that their estimator is biased to be ca. 300 years too old. doi.org/10.1101/2022.12.01.5…
Bravo "Annals of the Rheumatic Diseases" for giving the option to download a combined PDF containing both the manuscript and the Supplemental Material! This is a time saver, as I almost always end up needing to read something in the Supplemental Material.
"it’s also wise to simply not use filenames that contain spaces or other strange characters. Simple alphanumeric names with either dashes or underscores are best." @vsbuffalo in his book "Bioinformatics Data Skills".
'if standardized coefficients do not add information, they certainly do not add meaning. "To replace the unmeasurable by the unmeaningful is not progress" (Achen, 1977, p. 806).' - King G. American Journal of Political Science. 1986 Aug;30(3):666–687.
I have set up a Mastodon account at @[email protected], and used pruvisto.org/debirdify/ to easily populate my follows list. As that works by searching your Twitter profile for your Mastodon ID, please add your Mastodon ID to your profile so I can find you on Mastodon.
This guide to Mastodon is great.
Also trying out the #RStats semi-gration to mosstodon, I'm
@[email protected].
This guide by @djnavarro helped me blog.djnavarro.net/posts/202…
Rule 3 revised: If possible, cut words.
Learn Orwell’s rules of writing (although you may need to apply rule 6 to rule 5 occasionally): infusion.media/blog/george-o…
Sounds good to me. My call sign is KB3WIO.
You’re unable to view this Post because this account owner limits who can view their Posts. Learn more
“Mathematics may be compared to a mill of exquisite workmanship which grinds you stuff of any degree of fineness, but nevertheless what you get out depends on what you put in - … so pages of formulae will not get a definite result out of loose data.”
TH Huxley
@IanJMackay I think it is slightly amusing that you were the first one to like this tweet, as the source is the collection of quotes you assembled and gave me permission to share on my web site! :-) watson.hgen.pitt.edu/humor/s…
Daniel E. Weeks retweeted
Just how poorly does a polygenic score for LDL-C perform in a population that isn’t represented in its construction? Come check out my poster at #ASHG22 this afternoon (Wed) 3-4:45 to find out and chat!
Data cleaning principles, so clearly presented by @kwbroman
kbroman.org/Talk_DataCleanin…
Daniel E. Weeks retweeted
Congratulations Dr. Carlson and team!!!@jenccarlson
If @jenccarlson and her team had only been looking in genetic databases with people of European ancestry, they would have missed a big cholesterol discovery, reported this week in @HGGAdvances. bit.ly/3F1hnf6
ALT Photo and quote from Dr. Jenna Carlson: “It was through the generosity of thousands of Polynesian people that we were able to find this variant, which is a smoking gun that will spark new research into the biology underlying cholesterol.”
Science started using external peer review because the editorial board complained that “the job of refereeing and suggesting revisions for hundreds of technical papers is neither the best use of their time nor pleasant, satisfying work.”
Did someone mention peer review? Every scientist should read this historical perspective from @Melinda_Baldwin. Scientific review practices are post-Cold War and not introduced to improve papers. The past is a strange land. The future maybe stranger. doi.org/10.1086/700070
Saurabh teaching in our 5th Fogarty Workshop on Genetic Epidemiological Methods for Dissection of Complex Human Traits in Kolkata, Feb 28, 2009, about to answer a question with a very clear explanation. What a loss - condolences to his colleagues, friends, & family. @ISIKolkata
"The aspects of the review ... of most value ... – the strengths & weaknesses of the work ..., aspects of the findings & methods that excite them, questions that remain, how it fits in with other work & into the broader field – are all discarded once a decision is made." 1/2
"Peer review – the act of researchers reading, thinking carefully about, & commenting on their colleagues’ work – is an integral part of science" Often its value is squandered & never made public
2/2
Scientific Publishing: Peer review without gatekeeping doi.org/10.7554/eLife.83889
Massive news: eLife to abolish accept/reject decisions: papers will just be “peer reviewed”. Others can argue about this, but lots of interesting consequences. 1/9 elifesciences.org/articles/8…
