@TafLab

High risk, high reward research on cellular engineering, CRISPR, miRNAs and synthetic biology

 Weatherall Institute, Oxford
fulga-lab.org/
Joined July 2014
  • Tweets120
  • Following54
  • Followers131
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Fulga LAB retweeted
Addgene@Addgene31 May 2019
Precise regulation of mammalian gene expression by synthetic microRNA silencing-mediated fine-tuners (miSFITs) @TafLab hubs.ly/H0h-6fy0
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Tudor gave a talk on engineering mammalian cells -synthetic receptors, iSBH gRNA control, miSFIT gene tuning system- at Oxford IF's Innovation in Genomics event @if_oxford @MRC_WIMM #innovation #Genomics #IFOGenomics #syntheticbiology
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Just dropped our new preprint online where we used our Tri-C multiway 3C technologies to investigate promoter competition in chromatin self-interacting domains. A revised model for promoter competition based on multi-way chromatin interactions biorxiv.org/content/10.1101/…

A revised model for promoter competition based on multi-way chromatin interactions

Specific communication between gene promoters and enhancers is critical for accurate regulation of gene expression. However, it remains unclear how specific interactions between multiple regulatory...

biorxiv.org
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New work from @TafLab, @TFulga, @YaleMichaels, @MRC_WIMM decouples tRNA promoter and processing activities to enable Pol-II #CRISPR gRNA expression Out now @NatureComms go.nature.com/2YGAKCB
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Congratulations David for the new paper! The authors published their work on engineering highly specific Polymerase II driven tRNA-gRNA expression. These results will enable avenues of research both in genome engineering and basic tRNA biology. nature.com/articles/s41467-0…
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Choosing fluorescent proteins has never been easier thanks to FPbase! Learn more nature.com/articles/s41592-0… rdcu.be/brZJF @FPbase @TalleyJLambert
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Super proud for Clara's achievement at The 6th Oxbridge Women in Computer Science Conference as she won the best poster prize! Well done Clara. #TAFgotTalent
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Congratulations @OanaPelea for winning the DTC's 2019 Short Project Prize! #DTCSynbio #TAFgotTalent
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Synthetic microRNA silencing-mediated fine-tuners (miSFITs) to precisely control target gene expression levels in mammalian cells. @YaleMichaels, @TFulga, @mikebarnkob, @enzocerundolo, @MRC_WIMM, @TafLab go.nature.com/2BOEd8h
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Engineered microRNAs for fine tuning gene expression nature.com/articles/s41467-0…
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Our newest paper is out now in @NatureComms! New tool for engineering precise changes in gene expression levels! rdcu.be/bniEw
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Save the date! We are looking forward to hosting Assoc Prof Tudor Fulga from the @TafLab in early March
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Exciting work from Savage lab @SavageCatsOnly on increasing the versatility, programmability and safety of Cas9 using circular permutations. #CRISPR #Cas9 #FulgaFriday cell.com/cell/fulltext/S0092…
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New method from the Fulga Lab for fine-tuning gene expression now on BioRxiv! We used this tool to explore how antigen expression influences the anti-tumour immune response. doi.org/10.1101/352377
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New manuscript from Fulga Lab on engineering novel tRNA scaffolds for Pol-II specific CRISPR guide RNA expression now on BioRxiv biorxiv.org/content/early/20…
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Fulga LAB retweeted
MRC WIMM@MRC_WIMM23 Feb 2018
Congratulations to Alba Rodriguez Meira (Mead lab), @tdavenne (Rehwinkel Lab), Yale Michaels (@TafLab) and Chris Paluch (Davis/Cornall Labs)! Their presentations at yesterday's Student Presentation Day were chosen to feature at the @MRC_WIMM Day in April! #wimmgsa #phdlife
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Fulga LAB retweeted
MRC WIMM@MRC_WIMM17 Dec 2017
ICYMI- The @TafLab (@RDMOxford) published new results in @NatureComms interrogating RNA cis-regulatory elements using #CRISPR/Cas9 technology nature.com/articles/s41467-0…
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Congratulations to our RDM Graduate Prize winners 2017! Huw Colin-York, @Tom_Riffel & @quentinferry1 (@MRC_WIMM) have displayed research excellence throughout their studies, helping to progress their respective fields. Well done all! Learn more: goo.gl/HGhXJi
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Fulga LAB retweeted
MRC WIMM@MRC_WIMM15 Dec 2017
What is the role of intragenic non-coding RNA cis-regulatory elements (RREs) in gene regulation? The @TafLab developed a #CRISPR-based technology platform to examine this questions, published @NatureComms nature.com/articles/s41467-0…
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Fulga LAB retweeted
MRC WIMM@MRC_WIMM15 Dec 2017
Congratulations to Huw Colin-York (Eggeling and @FritzscheLab, @MRC_HIU), @quentinferry1 (@TafLab) and @Tom_Riffel (Jacobsen lab @MRC_MHU and Simon lab @MRC_HIU), for winning this year's @RDMOxford Graduate Student Prize! imm.ox.ac.uk/mrc-wimm-studen…
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