Philip Yeo Chair Professor in Medicine @NUSMedicine | Member of Academia Europaea (MAE) | AIMBE Fellow

Singapore
Joined April 2019
Thanks @NatureMedicine for this interview, and I am glad that the Drug Delivery Technologies developed in my lab can be highlighted. It is also my great honor to be alongside world's top scientists - Profs. Bob Langer, @SMitragotri, @ryanfdonnelly, etc. nature.com/articles/s41591-0…
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I also can't wait to build something meaningful here with an exceptional community. The best is yet to come.🧬🇸🇬 Grateful for the past, excited for the future.🙏
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Thrilled to share our latest @natrevbioeng paper with Profs. Bob Langer @MIT, Gaurav Gaiha @ragoninstitute, et al. In this Review, we evaluate clinical trials of HIV mRNA medicine and discuss persistent challenges in developing mRNA-based interventions against HIV. @harvardmed
mRNA technology for the prevention and treatment of HIV-1 infection dlvr.it/TQG89r
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We are delighted to announce that our article has been selected for the front cover feature in the 2026 First Issue of American Scientist!👉 "Messenger RNA Can Do More for Medicine" shar.es/agK6Yq @XiangangHuang @MGBResearchNews @harvardmed
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This integrative approach represents a notable advance in LNP characterization, offering a more mechanistic understanding of how structural and biophysical attributes influence functional performance. - Another fantastic work by @MJMitchell_Lab and his team! @NatureBiotech
Replying to @NatureBiotech
Research Briefing: Solution biophysics reveals the polydisperse structure of RNA lipid nanoparticles go.nature.com/47Mquhs rdcu.be/eNlNL
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New in @NatureNano: Systemic delivery of IL-10-mRNA NPs triggers strong immune surveillance in diverse tumor models. This #mRNA NP strategy may offer promise for overcoming recombinant IL-10's challenges in immunosuppressive tumors. nature.com/articles/s41565-0…
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RNACap can orally deliver liquid mRNA therapeutics to the intestines in response to intestinal pH, the resulting pressure release, and contractions science.org/doi/10.1126/scit… @ScienceTM
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The new issue of #ScienceTranslationalMedicine has arrived! Engineered capsules can deliver liquid mRNA therapeutics to treat intestinal disease in animals, the complement cascade offers a target in acute chest syndrome in sickle cell disease, and more. scim.ag/44Ut82f
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Our new paper is published as a Cover Story -"Eating the Message" in @ScienceTM. This paper demonstrates that oral mRNA delivery to the intestines is feasible using our RNACap design. Congrats to our Rising Star @XiangangHuang and the team!
Engineered “RNACaps” provide oral delivery of liquid #mRNA therapeutics to the intestines in small and large animals for the treatment of #colitis and could support the clinical translation of oral mRNA therapies. @WeiTaoLab @BrighamAnes @XiangangHuang scim.ag/3IwtODi
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By loading different types of mRNAs, new oral mRNA vaccines for infectious diseases and oral mRNA medicines for cancers are possible. This technology could also benefit the oral delivery of other types of biologics (e.g., nucleic acids and proteins) to tackle different diseases.
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The Tao Lab currently has one postdoc position opening. More information can be found on the page below: weitaolab.com/openings
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Modulating nano-bio interface via drug-framework hybridization to activate chemoimmunotherapy against glioma postoperative recurrence dlvr.it/TJx2mp #biomaterials #bioengineering
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Honored to be inducted as a Fellow into the American Institute for Medical and Biological Engineering @aimbe @BrighamWomens @harvardmed! Many thanks to my nominator, who is my real role model in many aspects! (Thanks to my friends for taking nice photos from different angles📸)
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