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Awesome to meet up with @NeilSavalia and celebrate acceptance of our paper on spatiotemporal NE dynamics at #winterbrain2024 (work with Samira Glaeser-Khan and @kwanalexc biorxiv.org/content/10.1101/…, using grab sensors from @yulonglilab )
Al Kaye retweeted
Enhancing cGMP signaling with psilocybin reduces head twitch and restructures the synaptic proteome while maintaining antidepressant response
doi.org/10.1038/s41386-026-0…
Al Kaye retweeted
Applications for the Wu Tsai Institute’s faculty search in neurocognition are due October 15.
We encourage outstanding early-career researchers using interdisciplinary approaches to study cognition within ecological, biological, or societal contexts to apply.
Join our collaborative research community at @Yale.
Apply: apply.interfolio.com/189343
Deadline: October 15, 2026
Details: wti.yale.edu/opportunities/f…
#KnowTogether #ScienceAtYale
Al Kaye retweeted
Grateful for two R01s recently: to develop tools for recording and perturbing biochemical dynamics in the brain (with @jinzhanglab), and to uncover what these dynamics do in vivo. Recruiting postdocs, grad students, and engineers to join our exploration. sites.wustl.edu/yaochenlab/p…
Al Kaye retweeted
MDMA enhances prefrontal plasticity and representational drift during fear extinction
biorxiv.org/content/10.64898…
Al Kaye retweeted
The Department of Neuroscience at Yale is hiring faculty members. We have 2 searches: one general (deadline Oct 15), one focused on computational neuroscience (deadline Nov 30). Apply! apply.interfolio.com/190736 & apply.interfolio.com/190740
Al Kaye retweeted
We get asked often - what is the duration of psilocybin's effects in the mouse brain? 🧠
There exist data, and now we have also measured it ourselves: Time to peak was 33 min and brain half-life was 56 min.
Part of a preprint on dendritic Ca2+ signals: biorxiv.org/content/10.64898…
Al Kaye retweeted
Congratulations to Grant Year 22 Pilot Project awardees: Drs. Daniel Munro (UCSD), Leah Harmon (Yale U.), Rebekah Schlitzer (Wake Forest U.), and Dayana Perez-Acuna (Yale U.). Additional information is here: medicine.yale.edu/keck/nida/….
Al Kaye retweeted
How does TMS — a treatment for depression — reshape dysfunctional brain circuits?
In our new Cell paper, we identify a cell type-specific prefrontal mechanism linking accelerated iTBS to antidepressant-like behavioral effects and circuit plasticity.
cell.com/cell/fulltext/S0092…
Al Kaye retweeted
Excited to share our new paper with @ScottWilke5’s lab! 🎉 Led by @michaelgongwer, we uncover how rTMS drives therapeutic effects through cell type–specific plasticity in the prefrontal cortex. A big step toward understanding its mechanisms—take a look!
sciencedirect.com/science/ar…
Al Kaye retweeted
Excited to share our new paper:
We uncover an LC→amygdala circuit linking β-adrenergic signaling to transcription regulation in defined amygdala neurons during reconsolidation—plus stress/elevated noradrenergic signaling at recall can strengthen memory.
cell.com/neuron/abstract/S08…
We're interested in hiring a post-baccalaureate research associate to work in circuit and systems neuroscience studies of anxiety. Please reach out - my email is listed at kayelab.com - if interested or share with undergraduate/recent grads who may be interested.
Al Kaye retweeted
Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @RhodesCollege!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! cell.com/cell-reports/fullte…
Al Kaye retweeted
Supported by a $5M grant from @wellcometrust, @YNeurosurgery @YalePsych have launched a study aimed at uncovering the neural & genomic mechanisms driving anxiety. Initial funding for pilot work came from Yale Center for Brain & Mind Health + @KavliAtYale.
medicine.yale.edu/news-artic…
Al Kaye retweeted
An interdisciplinary team of researchers from the departments of psychiatry and neurosurgery at @YaleMed has launched a pioneering study aimed at uncovering the neural and genomic mechanisms that drive anxiety. tinyurl.com/4k34b57r
Al Kaye retweeted
UCalgary is recruiting!
We are recruiting for the Novartis Research Chair in Schizophrenia Research (MD required)
See more info in the ad below, and feel free to reach out w/ questions about the institute, city, etc.,.
Please share!
universityaffairs.ca/search-…
Al Kaye retweeted
Memory researchers in New York, check this out 👇
I'm so excited for this conference! It's going to be a fantastic day of collaborative learning and discussion about all things memory 🧠
📢REGISTRATION IS NOW OPEN for the first annual New York Memory Hub conference! Join @IcahnMountSinai's @denisejcai @susana_mingote & @tristanshuman on Sept 26 for a day of talks & discussion about all things learning & memory🧠Learn More | Register Here: eventbrite.com/e/new-york-me…
So excited to participate in this collection of scientists across the translational spectrum developing new treatments #GRCPsychedelics
Great lineup of speakers from preclinical to clinical, drug discovery to plasticity, and animals to human research. 🔥
@RachelYehuda @ExistWell @zenbrainest @lab_nichols @akaye @KateNautiyal @ArgelAV @NUro_science @LabWalsh @ClaireFoldi @bita137 @KepecsLab @DR_WANG_SIBCB ...
Wonderful close to a really intellectually coherent and welcoming @PavlovSociety conference learning about the visual system and art #pavlovian2024
Al Kaye retweeted
Really amazing chairing a session on the locus coeruleus in behavior and physiology @PavlovSociety conference. Thank you to all the speakers! @Sciolino_Lab @akaye @thiagoarzua Lissa Riley ✨
