@bride_lab

Diverse and creative group of UTMB scientists, interdisciplinary investigation of pathogen-host interface involving obligate monocytotropic bacteria

Joined March 2021
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  • Following93
  • Followers90
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McBride Lab 2021!
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Graduation Day for two newly minted PhDs! It has been a privilege to mentor such talented young scientists! The sky is the limit for these two! @UTMBGSBS @UTMBPathRes
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GSBS faculty, students and staff had a great time honoring our awardees at the Inaugural GSBS Awards Ceremony this afternoon! Congratulations to all awardees and nominees!
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McBride lab holiday lunch 2022! Fortunate to work with this great group scientists! Looking forward to continued success in 2023!
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Congratulations to LaNisha Patterson for her successful defense today! She was such a force in my laboratory! Now she's ready to do great work at MD Anderson Cancer Center. @MDAndersonNews
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Enjoyed visiting and sharing some of our work at the University of Arkansas for Medical Sciences (UAMS) @UAMSMicroImmuno. Beautiful place and and faculty are doing some great work! GREAT chairperson too! @votheroski Thanks for hosting!
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This new study defines a novel prokaryotic SLiM mimetic that repurposes evolutionarily conserved eukaryotic signaling pathways to promote survival of an intracellular bacterium. Read it in full here: plos.io/3sJz8Z9
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Check out the nice work from Caitlan Byerly on Ehrlichia activation of Hedgehog signaling! #PLOSPathogens: Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic c ... dx.plos.org/10.1371/journal.…

Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic...

Author summary Ehrlichia chaffeensis is an obligately intracellular bacterium that preferentially infects and replicates within mononuclear phagocytes and survives intracellularly by modulating...

journals.plos.org
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Great visit with my friend, Dr. Adrian Billings, who joined us today as the UTMB Distinguished Alumnus. He delivered an inspiring speech to our graduates. Had a great day! – at League City, TX
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Today was graduation day for Graduate School of Biomedical Scineces and students in Experimental Pathology @utmbexpath. Congratulations! The future is bright!
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Post-doctoral research opportunity to investigate molecular & immunological mechanisms of Powassan virus transmission at the tick-virus-host interface. Please RT For additional information, send an email to [email protected]
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New in Science: A genetic study involving more than 2,000 dogs suggests that, contrary to popular belief, breed alone is a poor predictor of behavior. Read that research and more in this week's issue. ➡ fcld.ly/85l8lon
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A recent Science study analyzed thousands of connections between potential disease-associated mutations, specific proteins, and medical conditions, thereby providing a detailed map for use by future researchers. fcld.ly/jk3x6of #NationalProteinDay
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A recent Science analysis of data from U.S. military recruits suggests multiple sclerosis—a disease considered of unknown etiology—is a complication of infection with Epstein-Barr virus. Learn more ⬇ fcld.ly/sicotxm #SciencePerspective: fcld.ly/ehqno7q
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Exciting new study by predoctoral student Caitlan Byerly in my lab! Mimicry to exploit the Hedgehog pathway 💥 – at Galveston, TX
bioRxiv Microbiology@biorxiv_micrbio9 Feb 2022
Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic cellular program biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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McBride Lab retweeted
Cell@CellCellPress5 Feb 2022
In the latest issue! Omicron’s message on vaccines: Boosting begets breadth dlvr.it/SJPxQp
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Interesting article on existence of novel RNA viruses previously unknown. nature.com/articles/s41586-0… – at League City, TX

Petabase-scale sequence alignment catalyses viral discovery

Nature - Serratus, an open-source cloud-computing infrastructure, can be used to screen millions of nucleic acid sequencing libraries at the petabase scale, and has enabled many new RNA viruses to...

nature.com
Much deserved! Happy for you! – at Galveston, TX
Michael McBride@Michael7McBride24 Jan 2022
Blessed to receive an offer from the University of Central Oklahoma!! @CoachMcGuire_
Check out our new work! Ehrlichia SLiM ligand mimetic activates Notch signaling in human monocytes biorxiv.org/content/10.1101/… – at League City, TX

Ehrlichia SLiM ligand mimetic activates Notch signaling in human monocytes

Ehrlichia chaffeensis evades innate host defenses by reprogramming the mononuclear phagocyte through mechanisms that involve exploitation of multiple evolutionarily conserved cellular signaling...

biorxiv.org
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We are hiring 2-3 TT assistant/associate professors at the Dept. of Pathology, UTMB. We welcome applications by February 28, 2022. @ASTMH @ACAV_ASTMH @ACME_ASTMH @aaas @ASMicrobiology
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Congratulations to Dr. Jere McBride, Professor in the Dept. of Pathology, on a new R01 award. This 5-year @NIAIDFunding research grant award supports his project, "Ehrlichia Notch SLiM-activated oncoprotein inhibition of apoptosis." Great work @BrideJere @bride_lab.
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