McBride Lab (@bride_lab) header
McBride Lab (@bride_lab) profile picture

Diverse and creative group of UTMB scientists, interdisciplinary investigation of pathogen-host interface involving obligate monocytotropic bacteria

Joined March 2021
Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)Photo by McBride Lab (@bride_lab)
GSBS faculty, students and staff had a great time honoring our awardees at the Inaugural GSBS Awards Ceremony this afternoon! Congratulations to all awardees and nominees!
2
2
10
689
This new study defines a novel prokaryotic SLiM mimetic that repurposes evolutionarily conserved eukaryotic signaling pathways to promote survival of an intracellular bacterium. Read it in full here: plos.io/3sJz8Z9
3
4
Post-doctoral research opportunity to investigate molecular & immunological mechanisms of Powassan virus transmission at the tick-virus-host interface. Please RT For additional information, send an email to [email protected]
New in Science: A genetic study involving more than 2,000 dogs suggests that, contrary to popular belief, breed alone is a poor predictor of behavior. Read that research and more in this week's issue. ➡ fcld.ly/85l8lon
7
135
70
355
A recent Science study analyzed thousands of connections between potential disease-associated mutations, specific proteins, and medical conditions, thereby providing a detailed map for use by future researchers. fcld.ly/jk3x6of #NationalProteinDay
2
116
7
342
A recent Science analysis of data from U.S. military recruits suggests multiple sclerosis—a disease considered of unknown etiology—is a complication of infection with Epstein-Barr virus. Learn more ⬇ fcld.ly/sicotxm #SciencePerspective: fcld.ly/ehqno7q
5
84
17
267
McBride Lab retweeted
In the latest issue! Omicron’s message on vaccines: Boosting begets breadth dlvr.it/SJPxQp
11
25
We are hiring 2-3 TT assistant/associate professors at the Dept. of Pathology, UTMB. We welcome applications by February 28, 2022. @ASTMH @ACAV_ASTMH @ACME_ASTMH @aaas @ASMicrobiology
3
41
40
Congratulations to Dr. Jere McBride, Professor in the Dept. of Pathology, on a new R01 award. This 5-year @NIAIDFunding research grant award supports his project, "Ehrlichia Notch SLiM-activated oncoprotein inhibition of apoptosis." Great work @BrideJere @bride_lab.
7
6
2
38
A low dose of the Moderna #COVID19 vaccine generated long-lived T cell immunity that was equivalent between younger and older patients, and which could be enhanced by the presence of cross-reactive T cells, researchers report in Science. fcld.ly/usdfrq3
8
61
1
197
Replying to @ScottGottliebMD
@ScottGottliebMD says CDC "has a very retrospective mindset," unsuited to quick decision-making: "CDC should have raised their hand and said, we really don't have this." cbsn.ws/3tPrhZu
41
83
27
390
My new book on #Covid19, what went wrong and how we can prevent the next pandemic, is available for pre-order. I look at the systemic woes that exacerbated the crisis, and how we must view public health preparedness through the lens of national security. harpercollins.com/products/u…
213
100
1,067
DNA origami and silica beads reveal how immune cells decide when it is time to attack elifesciences.org/articles/6…
44
2
142
How do cats stay so clean? 🐈 Three-dimensional scans and thermal imaging have given unprecedented insight into cat grooming. Take a look on #InternationalCatDay: fcld.ly/ftrrobi
3
112
10
344
Several mammal species live in cold-water environments thanks to adaptations such as blubber and large size. A notable exception to this rule is the sea otter—so how do they stay warm? A new Science study finds a reason: skeletal muscle thermogenesis. fcld.ly/6rjjdar
4
52
6
196
McBride Lab retweeted
New study from Rogan et. al. from the McBride lab @UTMB_Pathology and @ihii_utmb shows Wnt SLiM mimetic effector activates Wnt signaling to promote #Ehrlichia infection. msphere.asm.org/content/6/2/… @ASMicrobiology #mSphere
3
2
10
CDK4/6 inhibitors induce chemokines secretion in breast cancer cells facilitating T cell infiltration into tumors and increasing vulnerability to adoptive T cell therapy. bit.ly/3g0YPPF
This time last year, physicians around the world prepared to treat a new disease—over and over and over again. Today, #COVID19 remains enigmatic—and deadly—but doctors have gleaned an aspirational strategy for treating it. fcld.ly/jrlvb40
4
117
3
305
A new X-ray crystallography screen of more than 5,000 drug compounds has found seven that bind to #SARSCoV2’s main protease and show target-specific antiviral activity. Of these, two show potential as candidates for preclinical testing. fcld.ly/e6rlm25
2
97
14
348
McBride Lab retweeted
Scientists identify a new mechanism in which RECQ1, a gene encoding DNA helicase, regulates disease-driving gene expression in ER-positive breast cancer cells. @MCBJournal skyw.io/TxHZqD
3
7