Studying collective cell behaviour. Interested in regeneration, detection of aberrant cells and tissue mechanics. (run by the Classenlab collective)
Freiburg University
Joined October 2019
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Excited to share our new bioRxiv preprint on tissue repair! Discover how tissue regeneration bypasses growth restrictions using the JAK/STAT-PDK1-S6K axis. Explore the metabolic links between tumor growth and wound healing. We’d love your feedback! #DevBio #Metabolism #Tumor – at Freiburg im Breisgau, Germany
PDK-1/S6K and mTORC1 bypass systemic growth restrictions to promote regeneration biorxiv.org/cgi/content/shor… #biorxiv_devbio
Congratulations, @fischericke for successfully defending your PhD! 🥂🎉
Don't forget to swing by on UDOLM (Universal Day of Low Motivation) for some motivational tea with us❤️ We miss your presence in the lab already and wish you all the best for your future adventures. – at Freiburg im Breisgau, Germany
Classenlab retweeted
Cancer is usually thought to be caused by permanent mutations in certain genes, but @classenlab explains how just temporarily disrupting silencing of gene expression in fruit flies can trigger a feedback loop that turns cells cancerous. go.nature.com/3W8mOBs
Have you ever wondered how our tissues stay healthy, and how they are able to identify and remove abnormal cells?
Click authors.elsevier.com/sd/arti… @CurrentBiology for the whole story. 1/9
#devbio #cellbio #tumor #axonguidance #cellcompetition #SFB850 #Ras #Drosophila #JNK #teneurin
ALT The image shows a zoomed in part of a wing imaginal disc with ectopic Robo2 expressing cells in cyan, JNK signaling activity in magenta, actomyosin (phalloidin staining) in grey and cleaved Dcp-1 (apoptosis) in yellow.
Cell surface proteins like Robo2 and Robo3 play a role in IFS, which is specifically activated by aberrant activation of fate specifying pathways including oncogenic RasV12. Robo2 and Robo3 do not play a role in classical cell competition models tied to metabolic fitness. 8/9
Congratulations, Jonas🍄, on successfully defending your bachelor's thesis!🥳 Wishing you all the best for your future endeavors! 🎓🌟 #ThesisDefense #Congratulations – at Freiburg im Breisgau, Germany
Our lab day out was a blast🥳! Ice skating, bowling, and the delicious food left us buzzing with joy❤️. Looking forward to more fun times ahead!#labdayout #teamfun – at Freiburg im Breisgau, Germany
Classenlab retweeted
Nov 8 is #FirstGen Day (in the US First Generation College Celebration Day)🎓🎊
We take this opportunity to honor the remarkable scientific and personal achievements of #firstgen researchers and students in CIBSS, @UniFreiburg and beyond #CelebrateFirstGen #RepresentationMatters
We had loads of fun carving our pumpkins! 🎃
Fun 🎃 #pumpkincarving 🎃 with @realArnoldLab 🐁 @classenlab 🪰 @GPyrowolakis lab 🪰 @WalentekLab 🐸 and delish dinner last week 👏👏👏
Our PhD student @Freyna_STEM did a stellar job presenting @fischericke amazing work on Interface Surveillance at #EDRC2023. Please check out the preprint biorxiv.org/content/10.1101/… Kudos to Friedericke, Anna & team! 👏 – at Lyon, France
We had a lot of fun, amazing science and discussions, and a wonderful time in lyon! Thank you and see you at #edrc2025
