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Genetically-encoded discovery are the heart of Derda Lab. A diverse and dynamic group located at UAlberta working on #phage #peptides & #glycans

Alberta, Canada
Joined April 2019
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To distract everyone from the devastating NIH news, I recommend reading this Mirror Image Life discussion in Science magazine science.org/doi/10.1126/scie… or popular press cbc.ca/radio/thecurrent/scie… and our view on this topic: TLDR: do not forget about Glycans! biorxiv.org/content/10.1101/…
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Excited to share our latest work on DNA-encoded liquid lectin array! This work would not have been possible without the amazing support and contributions of my colleagues at the University of Alberta!
Replying to @CellChemBiol
@CellChemBiol publication of Liquid Lectin Array (LiLA) led by Guilherme Meira Lima (scholar.google.com/citations…) PhD Student from @derda_lab and co-authors from @MatthewMacaule4 Lab, @glycocode (Lara Mahal), Raymond Lai et al, now in cell.com/cell-chemical-biolo…
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Online now! The liquid lectin array detects compositional glycocalyx differences using multivalent DNA-encoded lectins on phage by Guilherme Meira Lima, @RatmirDerda @derda_lab, et al. at @UAlberta @StanfordUChem @usponline dlvr.it/TFkMqZ #chembiol
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Congrats to all the GlycoNet researchers on their paper about the liquid lectin array (LiLA), which uses DNA-encoded #lectins to detect subtle glycocalyx differences and enhance our understanding of #glycan composition. @derda_lab @MatthewMacaule4 @glycocode @miratsojitra
Replying to @CellChemBiol
@CellChemBiol publication of Liquid Lectin Array (LiLA) led by Guilherme Meira Lima (scholar.google.com/citations…) PhD Student from @derda_lab and co-authors from @MatthewMacaule4 Lab, @glycocode (Lara Mahal), Raymond Lai et al, now in cell.com/cell-chemical-biolo…
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Replying to @CellChemBiol
@CellChemBiol publication of Liquid Lectin Array (LiLA) led by Guilherme Meira Lima (scholar.google.com/citations…) PhD Student from @derda_lab and co-authors from @MatthewMacaule4 Lab, @glycocode (Lara Mahal), Raymond Lai et al, now in cell.com/cell-chemical-biolo…
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The Liquid Lectin Array (LiLA) paper is out in @CellChemBiol. Congratulations to @Guilher63551077 for this amazing publication and it was my privilege to play a [small] part in this project. #Siglec #Glycotime #Phage #Glycans cell.com/cell-chemical-biolo…
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#FeaturedProtocol this week: #Liquidglycanarray (LiGA) platform to profile #glycan-lectin interactions on the surface of live cells bit.ly/4hjtZyE #Glycotime #Siglec
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Congrats to the GlycoNet team on this important research that advances our understanding of how glycans interact with proteins on live cells using the LiGA platform! @miratsojitra @RatmirDerda @MatthewMacaule4 @ednschmidt @Guilher63551077
Excited to report that protocol for DNA-encoded, Liquid Glycan Array (LiGA) is out in @NatureProtocols. In addition to the protocol, we report how the expression level of Siglecs and cell types affect their ability to bind to LiGA. nature.com/articles/s41596-0…
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A big thank you to @RatmirDerda and @MatthewMacaule4 for their mentorship! This wouldn't have reached the finish line without a lot of help from @Guilher63551077 @ednschmidt, Kelli (Macauley lab) and all past and presents members of @derda_lab
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DNA-encoded, Liquid Glycan Array (LiGA) and its application to cell-surface profiling is out in @NatureProtocols . Big thanks to @miratsojitra for leading the effort and @MatthewMacaule4 + members of Macaluley Lab and @derda_lab ! rdcu.be/dXaNJ
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I'm curious about any feedback from #Glycobiology #glycan #carbohydrate #glycotime community on @derda_lab preprint on DNA-encoded liquid #lectin arrays (LiLA). [LiLA] non-lineary amplifies detection of compositional differences of the cellular #glycocalyx biorxiv.org/content/10.1101/…
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Congratulations to our friend @miratsojitra who is now officially Dr. Sojitra. We are so proud of you. People will talk about how great you are as a scientist but we (Ann and me) will always remember you as our great friend.
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Here we show that peptide-glycan chimera can be made on the same instrument on solid support. Next, an instrument to make #glycopeptides for #glycotime studies will be revealed.
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Really proud to have worked with this guy and to have watched him grow both as a scientist and as a human being over his undergrad career. Congrats, @ryannqiu! :)
Congratulations to our superstar undergrad @ryannqiu for winning the best oral presentation award at the #wcucc2023!!! Very well deserved for all his hard work and dedication.
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Our star undergrad @ryannqiu gave an amazing talk at #WCUCC2023 !! Catch him at poster 47 to learn more about covalent inhibitors. Thank you @wcucc2023 organizers for putting up an amazing conference! #Peptide #Ligand #PhageDisplay
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Happy International Women's Day! We're celebrating women who have changed the world. Here's all of the amazing women who have received the #NobelPrize and their remarkable achievements at the time of the award. Who are the women who inspire you the most? #IWD2023
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From the University of Alberta, @CanadianPeptide CPPC student representative @ARUNIKAEKANAYA1 wins an oral presentation award at the @ampepsoc symposium! #peptides2022 @ualbertachem @derda_lab
One of our "Young Investigators," Arunika Ekanayake from University of Alberta, presents her very well received "Genetically Encoded Fragment-Based Discovery, GE-FBD, from Covalent and Non-Covalent Pharmacophores" talk. #Peptides2022
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Great meeting everyone. Congratulations!
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