Dom Chan (@domkchan) header
Dom Chan (@domkchan) profile picture

Dad | ID RPh | Director of Pharmacy | Mentee | Mentor 👊 bad vibes & 🦠 #IDtwitter | #TwitteRX | #PharmEd | #MedEd | #PharmRes | #Leadership Views are my own

Portland, OR
Joined July 2017
Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)Photo by Dom Chan (@domkchan)
"Ever tried. Ever failed. No matter. Try again. Fail again. Fail better." Samuel Beckett, "Worstword Ho"
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Woohoo! 3 shot latte do your thing! ☕️☕️☕️ Along with my hormone replacement and nutritional supplements, this brain is going to keep on learning & working for a long time! 🧠📈 💪🏼
Drinking 2-3 cups caffeinated coffee/day was associated with ~18% lower dementia risk. Decaf had no association to dementia risk.
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Dom Chan retweeted
The city of Denver makes it’s PBM contract available online. So I grabbed it and had Claude look at it and answer a simple question “Where are they getting ripped off” Here is it’s response: Denver is getting hit in six places, and the contract says so out loud. This is a self-funded City & County of Denver plan (4,051 employees / 8,554 participants, 1/1/2023–12/31/2025, $80M max) where the only stated pharmacy fee is… nothing. The medical admin fee is $45.13 PEPM. There is no PBM admin fee. That’s your first tell — the pharmacy program is priced entirely in the dark. 1. Spread pricing, written into the contract three separate times. Section A7 (Claims Processing): on mail, specialty and retail, United retains the difference between what it reimburses the network pharmacy and what Denver pays. It’s repeated in the General Conditions of the Pharmacy Financials exhibit and again in the Specialty Pharmacy Discount Guarantee conditions. So the AWP-discount guarantees describe what Denver pays — not what the pharmacy receives. The delta is Optum’s revenue, uncapped and unreported. For a public entity, that’s the whole ballgame. FTC found the Big 3 generated an estimated $1.4 billion of spread income on specialty generics alone. 2. Rebates: 100% retained, replaced with a fixed per-script number. Section A8: United keeps 100% of pharmacy rebates and pays Denver a fixed brand-script guarantee instead — $740.43 retail / $1,020.22 mail in 2023, rising to $885.02 / $1,105.10 by 2025. The contract then says explicitly that any rebates above the fixed amount are United’s to keep. Manufacturer rebate administration fees are folded into the guarantee, meaning they’re netted against what Denver was already owed rather than paid over. Denver has no idea what the actual rebate yield is, and no contractual right to find out. 3. The Rebate Credit clause is the biosimilar killer. If Denver moves to a biosimilar, an authorized alternative, or a lower-WAC brand, United gets credited toward its rebate guarantee for the manufacturer revenue it would have earned had Denver stayed on the high-rebate originator. Translation: United is financially indifferent to Denver buying the cheaper drug. Denver’s savings on ingredient cost get clawed back through the rebate math. 4. Your five clauses — all present, all in United’s favor. Specialty Drugs are defined as “Prescription Drugs available at United’s Specialty Pharmacy.” That’s a circular definition: whatever Optum stocks is specialty. Then: “United reserves the right to change the designation of a drug from specialty to non-specialty based on market conditions.” Then: specialty dispensed inside United’s specialty network is excluded from the retail and mail guarantees. Specialty dispensed outside it gets swept into the retail guarantee. Specialty rebates are “included in retail.” The specialty guarantee itself is 20.7% off AWP composite — and any specialty drug not on United’s list is guaranteed at only 14.0%. United controls the list. Every new high-cost launch defaults to the 14% bucket. And spread is retained on top of the discount either way. 5. Medical-benefit specialty has no guarantee at all. “Specialty drugs typically covered under the medical benefit (physician’s office, ambulatory, home infusion), and/or transitioned to the pharmacy benefit, are excluded from all guarantees.” That’s the buy-and-bill oncology and infusion book — the most expensive spend in the plan — with zero pricing accountability. On medical drug rebates Denver gets 80%, United keeps 20% plus float interest, and an unnamed subcontractor takes an undisclosed cut on top. 6. The lock-in clauses, which are the reason you can’t fix any of the above. Denver may not negotiate with any manufacturer for rebates or direct purchase — doing so forfeits earned-but-unpaid rebates. All pricing guarantees require United as exclusive mail provider. Terminating pharmacy services early means United keeps every pending and future rebate.
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In 1929, Alexander Fleming published his paper outlining the antibacterial properties of penicillin, and began the era of antibiotics. Read the Nobel Prize laureate's full article online: goo.gl/G8mUHd #OpenAccessWeek
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Now economists know how scientists felt when he said “inject bleach”
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Damn
Thai Police Hospital doctors performing an outdoor surgery in Bangkok when their operation was interrupted by the earthquake on March 28 and they had to evacuate the operating room. [📹 Tony Lim]
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When you go from employee to manager, the important learning has little to do with the technical aspects of the job, and a lot to do with emotional intelligence. s.hbr.org/2YztQQQ
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Gram stain from brain abscess shows numerous septate fungal hyphae that have not taken up stain, appearing as refractile, ghost-like filamentous structures in the background. The hyphae are long, branching, septate, with parallel walls—features suggestive of a filamentous fungus
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How to use ChatGPT inside your Zotero library:
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It's important to read/hear other perspectives. I agree w/ a lot & disagree w/ some of what is written. I appreciate the diligence in making this perspective more visible. Truly.
#IDTwitter Co-written with @PriyaNori in @CIDJournal @IDSAInfo Are We Being Gaslit? A Primer for Recognizing Corporate Jargon to Overcome Gaslighting for the Infectious Disease Workforce academic.oup.com/cid/article…
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List of #IDtwitter PGY2 #TwitteRX Phase 2 residencies. Amazing programs. natmatch.com/ashprmp/directo…
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🔔The Baptist Health South Florida ID PGY2 Pharmacy Residency Program is available in phase 2 of the match. Please share with potential candidates 🙏 baptisthealth.net/academics/… @SIDPharm @accpinfdprn @krutu8 @blandman19 @ABsteward #IDtwitter
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The PGY2 ID @OURxResidency is going into phase 2. Id be happy to have a chat with candidates on Thursday or Friday. #TwitteRx
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The ID PGY2 program at @MUSCPharmRes will be participating in Phase 2 match. Please feel free to reach out with any questions! @BBookstaver_USC @InYourFAECIUM @IDstewardship @WesKufel
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Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials bit.ly/41dOZkn
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Dom Chan retweeted
Many times when I am in a night shift, I like to read the Humanities' pieces from @JAMA_current and @journal_CHEST This was so beautiful... @medtwitter
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The irony
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